Neuromesodermal progenitors (NMps) emerge from the caudal lateral epiblast adjacent to the primitive streak and the node. NMps are molecularly defined as cells that co-express Sox2 and T/Bra and, thus, harbor the dual possibility of becoming neural or mesodermal. The study of NMps is important not only because of their central role in elongating the embryonic body axis but also because of the potential to recapitulate NMps in vitro and thereby generate spinal cord neurons in culture. Because NMps can be derived in vitro from human pluripotent cells, research in this area can provide new insight into embryo development and contribute to a better understanding of the human spinal cord development [1].