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A horizontal cylinder with a concave cross-section partially submerged in a liquid at a given position may permit multiple menisci around itself. The number and stabilities of the menisci are analysed, and how the menisci change during the processes of gradually hoisting and lowering the cylinder is explained by bifurcation theory. The restoring force on the concave cylinder and the rebounding potential energy (defined as the work done by the restoring force during the whole hoisting process to represent the potential rebounding capacity of a cylinder on water) are also investigated. The results show that, when the radius of the concave arc is smaller than the critical value, the concave cylinder at a given position permits multiple possible menisci. The equilibria form fold bifurcations with the position of the cylinder as the bifurcation parameter, and two successive fold bifurcations can form a one-fold hysteresis loop. The force–distance curve representing the relation between the restoring force and the position of the cylinder also has corresponding hysteresis loops, where the restoring force will jump (i.e. change discontinuously) at the bifurcation points. In contrast to a convex cylinder, a concave cylinder can have different values of the restoring force at the same height because of multiple menisci, and the values depend on whether it is hoisted or lowered. Under the condition of a fixed cross-sectional area, the optimal cross-sectional shape is determined when the maximum rebounding potential energy is reached, and it is close to the shape with the critical concave arc angle for the existence of multiple possible menisci. The cross-sections with concave parts are preferable to circular, laterally planed and corner-concave cross-sections. This paper provides an effective method of enhancing the restoring force and potential rebounding height of a robotic water strider insect or particles on the surface of water.
China, Japan, and South Korea, as three representative countries in East Asia, all have their own historical and cultural traditions, but they are closely related. In particular, Chinese culture has a great influence on Japan and Korea. The history of psychological testing in East Asia can be traced back to the ancient Chinese talent selection system. For example, an important content of the system of selecting officials in ancient China, the imperial examinations not only penetrated the middle and late stages of Chinese feudal society but also had a particularly profound impact on the entire East Asian civilization. However, despite some similarities in culture, these three countries have maintained their own ways of living. In this chapter we discuss the histories of psychological assessment of the three countries.
Drawing from the theory of territorial behavior, this article predicts the explanatory role of silence behavior in the relationship between knowledge hiding and hider's innovative behavior in Chinese organizations, and the potential of Zhongyong thinking in mitigating the detrimental effect of knowledge hiding. Results derived from a time-lagged and multi-source survey support our hypotheses. Specifically, knowledge hiding is negatively associated with the innovative behavior of the hider. Silence behavior mediates the relationship between knowledge hiding and innovative behavior. Meanwhile, Zhongyong thinking moderates the positive relationship between knowledge hiding and silence behavior, as well as the indirect relationship between knowledge hiding and innovative behavior through silence behavior. Theoretical and practical implications are discussed based on these findings.
At present, the study on autonomous unmanned ground vehicle navigation in an unstructured environment is still facing great challenges and is of great significance in scenarios where search and rescue robots, planetary exploration robots, and agricultural robots are needed. In this paper, we proposed an autonomous navigation method for unstructured environments based on terrain constraints. Efficient path search and trajectory optimization on octree map are proposed to generate trajectories, which can effectively avoid various obstacles in off-road environments, such as dynamic obstacles and negative obstacles, to reach the specified destination. We have conducted empirical experiments in both simulated and real environments, and the results show that our approach achieved superior performance in dynamic obstacle avoidance tasks and mapless navigation tasks compared to the traditional 2-dimensional or 2.5-dimensional navigation methods.
Whereas the existing literature on the relationship between parental behavior and family business succession mainly focuses on parental behavior in the business domain, we highlight the importance of parental behavior in the family domain. Integrating attachment theory, the family business succession literature, and person-job fit literature, our study proposes a theoretical framework hypothesizing that general self-efficacy and perceived person-job fit mediate the association between perceived parental care (an underrepresented family-domain-specific parental behavior) and next-generation family members’ succession intentions. This framework is tested by data from two surveys and further verified by qualitative interviews of next-generation family members. Multivariate analysis results suggest that next-generation family members’ general self-efficacy and perceived person-job fit played a sequential-mediating role in the relationship between perceived parental care and next-generation family members’ succession intentions. Our interviews not only confirm these results but also reveal new insights, particularly into the specific Chinese context in the study of family business succession.
Schistosomiasis has been subjected to extensive control efforts in the People's Republic of China (China) which aims to eliminate the disease by 2030. We describe baseline results of a longitudinal cohort study undertaken in the Dongting and Poyang lakes areas of central China designed to determine the prevalence of Schistosoma japonicum in humans, animals (goats and bovines) and Oncomelania snails utilizing molecular diagnostics procedures. Data from the Chinese National Schistosomiasis Control Programme (CNSCP) were compared with the molecular results obtained.
Sixteen villages from Hunan and Jiangxi provinces were surveyed; animals were only found in Hunan. The prevalence of schistosomiasis in humans was 1.8% in Jiangxi and 8.0% in Hunan determined by real-time polymerase chain reaction (PCR), while 18.3% of animals were positive by digital droplet PCR. The CNSCP data indicated that all villages harboured S. japonicum-infected individuals, detected serologically by indirect haemagglutination assay (IHA), but very few, if any, of these were subsequently positive by Kato-Katz (KK).
Based on the outcome of the IHA and KK results, the CNSCP incorporates targeted human praziquantel chemotherapy but this approach can miss some infections as evidenced by the results reported here. Sensitive molecular diagnostics can play a key role in the elimination of schistosomiasis in China and inform control measures allowing for a more systematic approach to treatment.
The Middle Miocene Climatic Optimum is known for abrupt events during the global cooling trend of the past 20 Ma. Its identification in the Tibetan Plateau can help explain the cause of the critical Middle Miocene climate transition in Central Asia. In this study, fine-grained mixed sediments widely distributed in the Miocene Qaidam Lake in the northern Tibetan Plateau were used as a sensitive indicator for palaeoclimate. Their geochemical characteristics were investigated, together with an analysis of 2600 m long successive gamma-ray logging data from the whole JS2 drillcore, to understand the mid-Miocene climate transition in the Tibetan Plateau. By comparing the gamma-ray curve of the mixed sediments with global temperature, the Middle Miocene Climatic Optimum event can be easily identified. Further, the detailed petrological features and geochemical data of lacustrine fine-grained mixed sediments from a 400 m drillcore show oxidizing, high-sedimentation rate and brackish-saline water conditions in a semi-arid climate during the Middle Miocene period, demonstrating a dryer climate in the Qaidam Basin than in the monsoon-sensitive regions in Central Asia. These fine-grained mixed sediments have recorded climate drying before 15.3 Ma that represents a climatic transition within the Middle Miocene Climatic Optimum; increasing carbonate-rich mixed sediments, decreasing algal limestone layers and decreasing lacustrine organic matter are indicators of this transition. Regional tectonic events include the retreat of the Paratethys from Central Asia at ∼15 Ma and the synchronous tectonic reorganization of the Altyn-Tagh fault system and the northeastern Tibetan Plateau. We find that global climate change is the primary factor affecting the overall characteristics and changes of the Neogene climate in the Qaidam Basin, including the occurrence of the Middle Miocene Climatic Optimum and the cooling and drying tendency, while the regional events are a secondary factor.
A miniaturized high-isolation quadplexer with wide upper-stopband based on open and short stub-loaded multimode-resonator is proposed in this paper. Based on the theory of multimode-resonator and stepped impedance resonator (SIR), the compact quadplexer is designed by using multimode-resonator and SIR. In order to further miniaturize the size of the circuit, the multimode resonator is employed as the common resonator to replace the common matching network of the quadplexer and the SIRs are curved. Equivalent topology circuit is given to analyze and design the quadplexer. Detailed analyses are given according to the equivalent circuits. The proposed compact quadplexer working at central frequencies of 1.8, 2.4, 2.8, and 3.5 GHz with over 40 dB isolation is finally simulated, fabricated, and measured. The measured results agree well with the simulated ones. The total size of the fabricated quadplexer is 0.36 λg × 0.42 λg.
Earlier studies examining structural brain abnormalities associated with cognitively derived subgroups were mainly cross-sectional in design and had mixed findings. Thus, we obtained cross-sectional and longitudinal data to characterize the extent and trajectory of brain structure abnormalities underlying distinct cognitive subtypes (“preserved,” “deteriorated,” and “compromised”) seen in psychotic spectrum disorders.
Methods.
Data from 364 subjects (225 patients with psychotic conditions and 139 healthy controls) were first used to determine the relationship of cognitive subtypes with cross-sectional measures of subcortical volume and cortical thickness. To probe neurodevelopmental abnormalities, brain structure laterality was examined. To examine whether neuroprogressive abnormalities persist, longitudinal brain structural changes over 5 years were examined within a subset of 101 subjects. Subsequent discriminant analysis using the identified brain measures was performed on an independent subject group.
Results.
Cross-sectional comparisons showed that cortical thinning and limbic volume reductions were most widespread in “deteriorated” cognitive subtype. Laterality comparisons showed more rightward amygdala lateralization in “compromised” than “preserved” subtype. Longitudinal comparisons revealed progressive hippocampal shrinkage in “deteriorated” compared with healthy controls and “preserved” subtype, which correlated with worse negative symptoms, cognitive and psychosocial functioning. Post-hoc discrimination analysis on an independent group of 52 subjects using the identified brain structures found an overall accuracy of 71% for classification of cognitive subtypes.
Conclusion.
These findings point toward distinct extent and trajectory of corticolimbic abnormalities associated with cognitive subtypes in psychosis, which can allow further understanding of the biological course of cognitive functioning over illness course and with treatment.
The general exotic capillary tube is a non-uniform capillary tube which permits an entire continuum of equilibrium menisci if applying a pressure $p=-\unicode[STIX]{x1D700}z$ at the tube inlet. The shapes of general exotic capillary tubes under positive and negative loads are determined mathematically. Lowering the pressure at the tube inlet slightly from the value $p=-\unicode[STIX]{x1D700}z$ causes the tube to completely drain out, while raising the pressure slightly forces the tube to fill up, which implies that the general exotic capillary tube is sensitive to pressure. The general exotic capillary tube is also related to meniscus stability. It is found that the boundary parameters $\unicode[STIX]{x1D712}_{1}$ of general exotic cylinders with arbitrary contact angle are equal to the critical values $\unicode[STIX]{x1D712}_{1}^{\ast }$ for determining the meniscus stability. Then, a convenient alternative to solving the Jacobi equation for determining $\unicode[STIX]{x1D712}_{1}^{\ast }$ is proposed based on the ‘exotic’ property.
A capillary surface in or around exotic cylinders cannot locate itself, since the configurations of the exotic cylinders with a variable radius permit an entire continuum of equilibrium menisci, all of which have the same potential energy. The ‘exotic’ property indicates that all the menisci have the smallest eigenvalues $\unicode[STIX]{x1D706}_{1}=0$ for the corresponding Sturm–Liouville problems without a volume constraint for stability analysis. Three types of exotic cylinders are addressed and the Sturm–Liouville problems with $\unicode[STIX]{x1D706}=0$ for stability analysis are solved numerically. Notably, the two-dimensional cases can be solved analytically. In the method of Slobozhanin & Alexander (Phys. Fluids, vol. 15, 2003, pp. 3532–3545), the stability of the meniscus is determined by comparing the boundary parameter $\unicode[STIX]{x1D712}_{1}$ and the critical value $\unicode[STIX]{x1D712}_{1}^{\ast }$, which is derived directly from the solution of the Sturm–Liouville problem with $\unicode[STIX]{x1D706}=0$. Results validate that the exotic cylinders have the boundary parameters $\unicode[STIX]{x1D712}_{1}=\unicode[STIX]{x1D712}_{1}^{\ast }$. Motivated by this observation, a new way to determine the critical value $\unicode[STIX]{x1D712}_{1}^{\ast }$ under pressure disturbances for stability analysis is proposed without solving the Sturm–Liouville problem with $\unicode[STIX]{x1D706}=0$.
Highly dense zirconia dental ceramic coatings were fabricated by aqueous electrophoretic deposition (EPD) and subsequently sintered between 1250 and 1450 °C. Microstructural examination revealed that aqueous EPDZrO2 coatings possessed a tetragonal phase structure and the grain size increased with increasing sintering temperature. Nanoindentation study proved that the aqueous EPDZrO2 coating also had excellent mechanical properties. The effect of different applied loads on hardness and elastic modulus of the 1350 °C-sintered sample at room temperature was investigated by the method of progressive multicycle measurement nanoindentation. The simulative experiment proved that hardness of aqueous EPDZrO2 exhibited reverse indentation size effect (ISE) behavior and then displayed the normal ISE response. The analysis indicates that the reverse ISE is attributed to the relaxation of surface stresses resulting from indentation cracks at small loads and normal ISE is caused by geometrically necessary dislocations. The tetragonal–monoclinic stress-induced phase transformation during nanoindentation is the primary cause of dental zirconia failures.
Fluorescence and phase transitions of a new Mg-Al-Eu ternary layered double hydroxide (LDH) and their dependence on thermal treatment were studied for the first time. Phase transitions occurred as the temperature increased from 400 to 1100°C. The process of phase transition is discussed in detail. The emissions of Eu3+ ions described by the 5D0–7FJ transition (J = 1,2,3,4), and especially for the 5D0–7FJ transition (J = 1,2) varied markedly with phase transformations from LDH, MgO, to mixtures of MgO and MgAl2O4. Moreover,strong emissions of Eu3+ ions are present in these new host materials. These results indicate that Mg-Al-Eu ternary LDH may be a potential candidate for materials applied in fluorescent devices.
A model for calculating the force profile and the moment profile of a floating body in two dimensions with an arbitrary cross-section is proposed. Three types of cross-sections with different contact angles and densities are calculated by using the model to determine the vertical and rotational equilibria and their stabilities. Results show that the model can be applied to convex floating bodies with finitely many sharp edges. The study is then extended to investigate the surface tension effects on the vertical and rotational stabilities by varying the following parameters: the radii of curvature of the solid surface at the contact lines and the size of floating body. In general, the smaller the radii of curvature the better the vertical and rotational stabilities. However, for the contact angle $\unicode[STIX]{x1D703}=0$ (or $\unicode[STIX]{x1D703}=\unicode[STIX]{x03C0}$) the radii of curvature have no effect on the vertical stability of the floating body. By varying the size of the floating body, it is found that the vertical and rotational stabilities of mesoscale floating bodies vary continuously between the stabilities of the macroscale and microscale floating bodies with other parameters remaining unchanged.
Previous studies have demonstrated adverse mental health effects of Pb exposure. The purpose of this study is to investigate the relationship between consumption of preserved egg (PE), a high-Pb-containing food and depressive symptoms among adults in China. A sample of 25 213 adults (mean age 41·4 (sd 11·8) years; males, 53·9 %) in Tianjin, China, was studied in a cross-sectional analysis. Dietary intake including PE was assessed using a valid self-administered FFQ. Depressive symptoms were assessed using the Self-Rating Depression Scale (SDS). The association was estimated by OR using logistic regression models adjusted for multiple confounders. The prevalence of elevated depressive symptoms was 6·6 % (SDS≥50). Compared with the least frequent PE consumption (<once/week), multivariable adjusted OR for elevated depressive symptoms were 1·52 (95 % CI 1·28, 1·81), 2·24 (95 % CI 1·76, 2·81) and 3·31 (95 % CI 2·52, 4·30) for consumption of once, 2–3 times and ≥4 times/week, respectively (Pfor trend<0·0001), indicating a clear dose–response relationship. The results suggested that higher consumption of PE was strongly associated with depressive symptoms among adults in China. These findings underscore the need to consider dietary Pb exposure as a risk factor for psychological distress.
Kawasaki disease, which is characterised by systemic vasculitides accompanied by acute fever, is regularly treated by intravenous immunoglobulin to avoid lesion formation in the coronary artery; however, the mechanism of intravenous immunoglobulin therapy is unclear. Hence, we aimed to analyse the global expression profile of serum exosomal proteins before and after administering intravenous immunoglobulin.
Methods
Two-dimensional electrophoresis coupled with mass spectrometry analysis was used to identify the differentially expressed proteome of serum exosomes in patients with Kawasaki disease before and after intravenous immunoglobulin therapy.
Results
Our analysis revealed 69 differential protein spots in the Kawasaki disease group with changes larger than 1.5-fold and 59 differential ones in patients after intravenous immunoglobulin therapy compared with the control group. Gene ontology analysis revealed that the acute-phase response disappeared, the functions of the complement system and innate immune response were enhanced, and the antibacterial humoral response pathway of corticosteroids and cardioprotection emerged after administration of intravenous immunoglobulin. Further, we showed that complement C3 and apolipoprotein A-IV levels increased before and decreased after intravenous immunoglobulin therapy and that the insulin-like growth factor-binding protein complex acid labile subunit displayed reverse alteration before and after intravenous immunoglobulin therapy. These observations might be potential indicators of intravenous immunoglobulin function.
Conclusions
Our results show the differential proteomic profile of serum exosomes of patients with Kawasaki disease before and after intravenous immunoglobulin therapy, such as complement C3, apolipoprotein A-IV, and insulin-like growth factor-binding protein complex acid labile subunit. These results may be useful in the identification of markers for monitoring intravenous immunoglobulin therapy in patients with Kawasaki disease.
Previous studies have supported the theory that there is a positive association between ferritin and carotid atherosclerosis in Western people. Diet plays an important role in determining serum ferritin concentration. Asian dietary patterns are different from Western dietary patterns, implying that there may be a difference in the association of ferritin with carotid atherosclerosis between Asian and Western people. However, few studies focus on the association between ferritin and carotid atherosclerosis among Asians. The aim of this study was to investigate how serum ferritin levels are associated with carotid atherosclerosis in an Asian adult population. A cross-sectional assessment was performed in 8302 adults in Tianjin, China. Carotid intima-media thickness (IMT) and plaques were assessed using ultrasonography, and serum ferritin was measured using the protein chip-chemiluminescence method. Multiple logistic regression analysis was used to examine the association between quartiles of serum ferritin concentration and carotid atherosclerosis. In the present study, the overall prevalence of IMT and carotid plaques in participants is 29·2 and 22·7 %, respectively. In women, after adjustments for potentially confounding factors, the OR of IMT and carotid plaques by increasing serum ferritin quartiles were 1·00, 1·39 (95 % CI 0·98–1·99), 1·39 (95 % CI 0·99–1·97), 1·81 (95 % CI 1·30–2·55) (Pfor trend<0·001) and 1·00, 1·24 (95 % CI 0·89–1·73), 1·18 (95 % CI 0·85–1·65), 1·59 (95 % CI 1·15–2·20) (Pfor trend<0·01), respectively. However, no association was found between serum ferritin and carotid atherosclerosis in men. The study demonstrated that increased serum ferritin levels are independently associated with IMT and carotid plaques in Asian women but not in Asian men.
A novel stainless steel porous twisted wire material (PTWM) is made of twisted short wires by compaction followed by vacuum high-temperature solid-phase sintering. The twisted short wires are fabricated by using a self-developed rotary multicutter tool to cut stainless steel wire ropes. The PTWMs with 46–70% porosities have been investigated in terms of porous structures and Charpy impact behavior. The PTWMs with spatial composite intertexture structures exhibit interconnected open-pore microstructures with a variety of shapes and sizes. The pore size distributions became convergent with decreasing porosities. The span of pore distribution of the PTWM with a diameter of 90 μm was half than that of the PTWM with a diameter of 160 μm under 65–66% porosity. The impact toughness of the former is 2.6 times than that of the latter. By increasing the porosity from 46 to 70%, the impact toughness decreases from 17.9 to 9.1 J/cm2. Macroscopically integral failure-morphologies of the PTWMs present mixed ductile–brittle failure mechanisms, but microscopic impact deformation and failure mechanisms mainly show the ductile failure and fracture of pore skeletons. The PTWMs demonstrate complex energy absorption mechanisms.
The three-plate system in which a vertical plate is located between two spaced parallel plates partially immersed in an infinite water bath in a downward gravity field is considered. With different contact angles and distance between the plates on both sides, the force profiles of the middle plate in this three-plate system are investigated using the Young–Laplace equation in two dimensions, and five non-trivial qualitative force profiles are found to possibly depend on the contact angles and the distance. The study is then extended to the qualitative changes of stability and behaviours in the system, and the striking properties related to the bifurcation theory come to light. Results show that, for different contact angles, there are at most eight possible bifurcation diagrams where the distance between the plates on both sides is chosen as the bifurcation parameter. By analysing the force profile of the middle plate in each of the eight bifurcation diagrams, the stabilities of the equilibria of the plate can be obtained. The number and the stabilities of equilibria will change when the bifurcation parameter passes the critical value.
In the present study, we evaluated the reproducibility and validity of dietary patterns among Chinese adult populations. A random subsample of 203 participants (aged 31–80 years) from a community-based nutrition and health survey was enrolled. An eighty-seven-item FFQ was administered twice (FFQ1 and FFQ2) 1 year apart; four 3 consecutive day, 24-h dietary recalls (24-HDR, as a reference method) were performed between the administrations of the two FFQ every 3 months. Dietary patterns from three separate dietary sources were derived using factor analysis based on twenty-eight predefined food groups. Comparisons between dietary pattern scores were made by using Pearson’s or intraclass correlation coefficients (ICC), cross-classification analysis, weighted κ statistic and Bland–Altman plots; the four major dietary patterns identified from FFQ1, FFQ2 and 24-HDR were similar. Regarding reproducibility, ICC for z-scores between FFQ1 and FFQ2 were all >0·6 for dietary patterns. The ‘animal and plant protein’ pattern had the highest ICC of 0·870. For validity, the adjusted Pearson’s correlation coefficients for dietary pattern z-scores between two FFQ and the mean of four 3 consecutive day 24-HDR ranged from 0·387 for the ‘Chinese traditional’ pattern to 0·838 for the ‘animal and plant protein’ pattern. More than 75 % of the participants were classified into the same or adjacent quartile, and <5 % were misclassified into opposite quartiles. The weighted κ ranged from 0·259 to 0·680. Bland–Altman plots indicated that no significant deviation was found between two dietary assessment methods. Our findings indicate a good reasonable reproducibility and a reasonable validity of dietary patterns derived by factor analysis in China.