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A Clinician's Guide to Statistics and Epidemiology in Mental Health
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Book description

Accessible and clinically relevant, A Clinician's Guide to Statistics and Epidemiology in Mental Health describes statistical concepts in plain English with minimal mathematical content, making it perfect for the busy health professional. Using clear language in favour of complex terminology, limitations of statistical techniques are emphasized, as well as the importance of interpretation - as opposed to 'number-crunching' - in analysis. Uniquely for a text of this kind, there is extensive coverage of causation and the conceptual, philosophical and political factors involved, with forthright discussion of the pharmaceutical industry's role in psychiatric research. By creating a greater understanding of the world of research, this book empowers health professionals to make their own judgments on which statistics to believe - and why.


'Excellent … unique and completely original … Clinicians will gain a better understanding of how to apply research to their practice. Researchers will be able to improve their research by increasing their awareness of the misuse of statistical methods.'

Source: The Canadian Journal of Psychiatry

'… nuanced explanations and reasoning …'

Source: Doody's Reviews

'… uses a lot of relevant clinical examples … easy to read introduction … Excellent.'

Source: BMA Medical Book Awards reviewer

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Abramson, J. (2004) Ovedosed America: The Broken Promise of American Medicine. New York: Harper Collins.
Abramson, J. H. and Abramson, Z. H. (2001) Making Sense of Data: A Self-Instruction Manual on the Interpretation of Epidemiological Data. New York: Oxford University Press.
Altshuler, L., Suppes, T., Black, D., et al. (2003) Impact of antidepressant discontinuation after acute bipolar depression remission on rates of depressive relapse at 1-year follow-up. Am J Psychiatry, 160, 1252–62.
American College of Neuropsychopharmacology (2004) Executive summary: Preliminary report of the task force on SSRI's and suicidal behavior in youth. Available at:, accessed January 22, 2009.
Andrews, G., Anstey, K., Brodaty, H., Issakidis, C. and Luscombe, G. (1999) Recall of depressive episode 25 years previously. Psychol Med, 29, 787–91.
Angell, M. (2005) The Truth About the Drug Companies. New York: Random House.
Barbui, C., Cipriani, A., Malvini, L. and Tansella, M. (2006) Validity of the impact factor of journals as a measure of randomized controlled trial quality. J Clin Psychiatry, 67, 37–40.
Basoglu, M., Marks, I., Livanou, M. and Swinson, R. (1997) Double-blindness procedures, rater blindness, and ratings of outcome. Observations from a controlled trial. Arch Gen Psychiatry, 54, 744–8.
Baxt, W. G., Waeckerle, J. F., Berlin, J. A. and Callaham, M. L. (1998) Who reviews the reviewers? Feasibility of using a fictitious manuscript to evaluate peer reviewer performance. Ann Emerg Med, 32, 310–7.
Bayes, T. and Price, R. (1763) An essay toward solving a problem in the doctrine of chances. Philos Trans R Soc London, 53, 370–418. Available at
Benson, K. and Hartz, A. J. (2000) A comparison of observational studies and randomized, controlled trials. N Engl J Med, 342, 1878–86.
Berry, D. A. (1993) A case for Bayesianism in clinical trials. Stat Med, 12, 1377–93; discussion 1395–404.
Blackwelder, W. C. (1982) “Proving the null hypothesis” in clinical trials. Control Clin Trials, 3, 345–53.
Blank, A. (2006) Swan's way. JAMA, 296, 1041–2.
Bolwig, T. G. (2006) Psychiatry and the humanities. Acta Psychiatr Scand, 114, 381–3.
Bowden, C., Calabrese, J., McElroy, S., et al. (2000) A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder. Arch Gen Psychiatry, 57, 481–9.
Bowden, C., Calabrese, J., Sachs, G., et al. (2003) A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. Arch Gen Psychiatry, 60, 392–400.
Brown, H. (2007) How impact factors changed medical publishing – and science. BMJ, 334, 561–4.
Buchkowsky, S. S. and Jewesson, P. J. (2004) Industry sponsorship and authorship of clinical trials over 20 years. Ann Pharmacother, 38, 579–85.
Cade, J. F. (1971) Contemporary challenges in psychiatry. Aust N Z J Psychiatry, 5, 10–17.
Calabrese, J. R., Bowden, C. L., Sachs, G. S., et al. (1999) A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group. J Clin Psychiatry, 60, 79–88.
Calabrese, J. R., Suppes, T., Bowden, C. L. et al. (2000) A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid-cycling bipolar disorder. Lamictal 614 Study Group. J Clin Psychiatry, 61, 841–50.
Calabrese, J., Bowden, C., Sachs, G., et al. (2003) A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently depressed patients with bipolar I disorder. J Clin Psychiatry, 64, 1013–24.
Calabrese, J. R., Keck, P. E., JR., Macfadden, W., et al. (2005) A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression. Am J Psychiatry, 162, 1351–60.
Calabrese, J. R., Huffman, R. F., White, R. L., et al. (2008) Lamotrigine in the acute treatment of bipolar depression: results of five double-blind, placebo-controlled clinical trials. Bipolar Disord, 10, 323–33.
Carroll, B. J. (2004) Adolescents with depression. JAMA, 292, 2578.
Carroll, B. J. (2006) Ten rules of academic life: reflections on the career of an affective disorders researcher. J Affect Disord, 92, 7–12.
Cohen, J. (1994) The earth is round (p < .05). Am Psychol, 49, 997–1003.
Cohn, J. B., Collins, G., Ashbrook, E. and Wernick, J. F. (1989) A comparison of fluoxetine, imipramine and placebo in patients with bipolar depressive disorder. Int Clin Psychopharmacol, 4, 313–14.
Das, A. K., Olfson, M., Gameroff, M. J., et al. (2005) Screening for bipolar disorder in a primary care practice. JAMA, 293, 956–63.
Davidoff, F., Deangelis, C. D., Drazen, J. M., et al. (2001) Sponsorship, authorship, and accountability. JAMA, 286, 1232–4.
Dawson, B. and Trapp, R. (2001) Basic and Clinical Biostatistics. New York: McGraw-Hill.
Dennett, D. (2000) Postmodernism and truth. In J. Hintikka, S. Neville, E. Sosa and A. Olsen, eds., Proceedings of the 20th World Congress of Philosophy, Volume 8. Charlottesville, VA: Philosophy Documentation Center.
Doll, R. (2002) Proof of causality: deduction from epidemiological observation. Perspect Biol Med, 45, 499–515.
Emanuel, E. J. and Miller, F. G. (2001) The ethics of placebo-controlled trials – a middle ground. N Engl J Med, 345, 915–19.
Eysenck, H. J. (1994) Meta-analysis and its problems. BMJ, 309, 789–92.
Feinstein, A. R. (1977) Clinical Biostatistics. St. Louis: Mosby.
Feinstein, A. R. (1995) Meta-analysis: statistical alchemy for the 21st century. J Clin Epidemiol, 48, 71–9.
Feinstein, A. R. and Horwitz, R. I. (1997) Problems in the “evidence” of “evidence-based medicine”. Am J Med, 103, 529–35.
Fink, M. and Taylor, M. A. (2007) Electroconvulsive therapy: evidence and challenges. JAMA, 298, 330–2.
Fink, M. and Taylor, M. A. (2008) The medical evidence-based model for psychiatric syndromes: return to a classical paradigm. Acta Psychiatr Scand, 117, 81–4.
Fisher, R. (1971 [1935]) The Design of Experiments, 9th edn. New York: Macmillan.
Fletcher, W. (1907) Rice and beri-beri: preliminary report on an experiment conducted at the Kuala Lumpur Lunatic Asylum. Lancet, i, 1776–9.
Forster, E. F. (1979) Some ethical considerations in the development of psychopharmacological research and practice in the future. Prog Neuropsychopharmacol, 3, 277–80.
Foucault, M. (1994) The Birth of the Clinic. New York: Vintage.
Friedman, L., Furberg, C. and Demets, D. (1998) Fundamentals of Clinical Trials, 3rd edn. New York: Springer.
Gehlbach, S. (2006) Interpreting the Medical Literature. New York: McGraw-Hill.
Ghaemi, S. N. (2003) The Concepts of Psychiatry: A Pluralistic Approach to the Mind and Mental Illness. Baltimore, MD: Johns Hopkins University Press.
Ghaemi, S. N. (2007) Mood Disorders: A Practical Guide, 2nd edn. Philadelphia: Lippincott, Williams, and Wilkins.
Ghaemi, S. N. (2008) Toward a Hippocratic psychopharmacology. Can J Psychiatry, 53, 189–96.
Ghaemi, S. N. and Goodwin, F. K. (2007) The ethics of clinical innovation in psychopharmacology: challenging traditional bioethics. Philos Ethics Humanit Med, 2, 26.
Ghaemi, S. N., Soldani, F. and Hsu, D. J. (2003) Evidence-based pharmacotherapy of bipolar disorder. Int J Neuropsychopharmacol, 6, 303–8.
Ghaemi, S. N., Miller, C. J., Rosenquist, K. J. and Pies, R. (2005) Sensitivity and specificity of the Bipolar Spectrum Diagnostic Scale for detecting bipolar disorder. J Affect Disord, 84, 273–7.
Ghaemi, S. N., Gilmer, W. S., Goldberg, J. F., et al. (2007) Divalproex in the treatment of acute bipolar depression: a preliminary double-blind, randomized, placebo-controlled pilot study. J Clin Psychiatry, 68, 1840–4.
Ghaemi, S. N., Shirzadi, A. and Filkowski, M. (2008a) Publication bias and the pharmaceutical industry: the case of lamotrigine in bipolar disorder. Medscape J Med, 9, 211.
Ghaemi, S. N., Wingo, A. P., Filkowski, M. A. and Baldessarini, R. J. (2008b) Long-term antidepressant treatment in bipolar disorder: meta-analyses of benefits and risks. Acta Psychiatr Scand, 118, 347–56.
Gijsman, H. J., Geddes, J. R., Rendell, J. M., Nolen, W. A. and Goodwin, G. M. (2004) Antidepressants for bipolar depression: a systematic review of randomized, controlled trials. Am J Psychiatry, 161, 1537–47.
Goldberg, J. F. and Whiteside, J. E. (2002) The association between substance abuse and antidepressant-induced mania in bipolar disorder: a preliminary study. J Clin Psychiatry, 63, 791–5.
Goodman, S. N. (1999) Toward evidence-based medical statistics. 2: The Bayes factor. Ann Intern Med, 130, 1005–13.
Goodwin, F. K. and Jamison, K. R. (2007) Manic Depressive Illness, 2nd edn. New York: Oxford University Press.
Goodwin, G. M., Bowden, C. L., Calabrese, J. R., et al. (2004) A pooled analysis of 2 placebo-controlled 18-month trials of lamotrigine and lithium maintenance in bipolar I disorder. J Clin Psychiatry, 65, 432–41.
Gyulai, L., Bowden, C., McElroy, S., et al. (2003) Maintenance efficacy of divalproex in the prevention of bipolar depression. Neuropsychopharmacology, 28, 1374–82.
Hammad, T. A., Laughren, T. and Racoosin, J. (2006) Suicidality in pediatric patients treated with antidepressant drugs. Arch Gen Psychiatry, 63, 332–9.
Healy, D. (2001) The Creation of Psychopharmacology. Cambridge, MA: Harvard University Press.
Healy, D. (2008) Mania. Baltimore: Johns Hopkins University Press.
Hill, A. B. (1962) Statistical Methods in Clinical and Preventive Medicine. New York: Oxford University Press.
Hill, A. B. (1965) The environment and disease: association or causation? Proc R Soc Med, 58, 295–300.
Hill, A. B. (1971) Principles of Medical Statistics, 9th edn. New York: Oxford University Press.
Hirschfeld, R. M., Williams, J. B., Spitzer, R. L., et al. (2000) Development and validation of a screening instrument for bipolar spectrum disorder: the Mood Disorder Questionnaire. Am J Psychiatry, 157, 1873–5.
Hirschfeld, R. M., Calabrese, J. R., Weissman, M. M., et al. (2003) Screening for bipolar disorder in the community. J Clin Psychiatry, 64, 53–9.
Horton, R. (2002a) The hidden research paper. JAMA, 287, 2775–8.
Horton, R. (2002b) Postpublication criticism and the shaping of clinical knowledge. JAMA, 287, 2843–7.
Horton, R. (2004) The dawn of McScience. New York Review of Books, 51, 7–9.
Hrobjartsson, A. and Gotzsche, P. C. (2001) Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment. N Engl J Med, 344, 1594–602.
Hummer, M., Holzmeister, R., Kemmler, G., et al. (2003) Attitudes of patients with schizophrenia toward placebo-controlled clinical trials. J Clin Psychiatry, 64, 277–81.
Hunt, M. (1997) How Science Takes Stock: The Story of Meta-Analysis. London: Russell Sage Foundation.
Ioannidis, J. P. (2005) Contradicted and initially stronger effects in highly cited clinical research. JAMA, 294, 218–28.
Jaeschke, R., Guyatt, G. and Sackett, D. L. (1994) Users’ guides to the medical literature. III. How to use an article about a diagnostic test. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA, 271, 389–91.
James, W. (1956 [1897]) Is life worth living? The Will to Believe and Other Essays in Popular Philosophy. New York: Dover.
Jaspers, K. (1997 [1959]) General Psychopathology: Volumes 1 and 2. Baltimore, MD: Johns Hopkins University Press.
Jefferson, T., Alderson, P., Wager, E. and Davidoff, F. (2002) Effects of editorial peer review: a systematic review. JAMA, 287, 2784–6.
Joffe, R. T., MacQueen, G. M., Marriott, M. and Young, L. T. (2005) One-year outcome with antidepressant–treatment of bipolar depression. Acta Psychiatr Scand, 112, 105–9.
Jorge, R. E., Robinson, R. G., Arndt, S. and Starkstein, S. (2003) Mortality and poststroke depression: a placebo-controlled trial of antidepressants. Am J Psychiatry, 160, 1823–9.
Kanigel, R. (1986) Apprentice to Genius: The Making of a Scientific Dynasty. New York: Macmillan.
Katz, M. (2003) Multivariable analysis: a primer for readers of medical research. Ann Intern Med, 138, 644–50.
Keitner, G. I., Solomon, D. A., Ryan, C. E., et al. (1996) Prodromal and residual symptoms in bipolar I disorder. Compr Psychiatry, 37, 362–7.
Kennedy, J. (1962) Public Papers of the Presidents of the United States. Washington DC: Office of the Federal Register.
Kent, D. M. and Hayward, R. A. (2007) Limitations of applying summary results of clinical trials to individual patients: the need for risk stratification. JAMA, 298(10), 1209–12.
Kirsch, I., Deacon, B. J., Huedo-medina, T. B., et al. (2008) Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration. PLoS Med, 5, e45.
Kojeve, A. (1980) Introduction to the Reading of Hegel. New York: Cornell University Press.
Kraemer, H. C. and Kupfer, D. J. (2006) Size of treatment effects and their importance to clinical research and practice. Biol Psychiatry, 59, 990–6.
Kushner, S. F., Khan, A., Lane, R. and Olson, W. H. (2006) Topiramate monotherapy in the management of acute mania: results of four double-blind placebo-controlled trials. Bipolar Disord, 8, 15–27.
Lang, J. M., Rothman, K. J. and Cann, C. I. (1998) That confounded P-value. Epidemiology, 9, 7–8.
Leon, A. C. (2004) Multiplicity-adjusted sample size requirements: a strategy to maintain statistical power with Bonferroni adjustments. J Clin Psychiatry, 65, 1511–4.
Levine, R. and Fink, M. (2006) The case against evidence-based principles in psychiatry. Med Hypotheses, 67, 401–10.
Lexchin, J., Bero, L. A., Djulbegovic, B. and Clark, O. (2003) Pharmaceutical industry sponsorship and research outcome and quality: systematic review. BMJ, 326, 1167–70.
Louis, P. C. A. (1835) Researches on the Effects of Bloodletting in some Inflammatory Diseases. (Reprinted by the Classics of Medicine Library, Birmingham, Alabama, 1986.)
Mack, J. (1995) Abduction: Human Encounters with Aliens. New York: Ballantine.
Mackay, A. (1991) A Dictionary of Scientific Quotations. Boca Raton, FL: CRC Press.
Makkreel, R. (1992) Dilthey: Philosopher of the Human Studies. Princeton, NJ: Princeton University Press.
Manwani, S. G., Pardo, T. B., Albanese, et al. (2006) Substance use disorder and other predictors of antidepressant-induced mania: a retrospective chart review. J Clin Psychiatry, 67, 1341–5.
March, J., Silva, S., Petrycki, S., et al. (2004) Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression: Treatment for Adolescents With Depression Study (TADS) randomized controlled trial. JAMA, 292, 807–20.
McHugh, P. R. (1996) Hippocrates a la mode. Nat Med, 2, 507–9.
Menand, L. (2001) The Metaphysical Club. New York: Farrar, Strauss, and Giroux.
Miettinen, O. and Cook, E. (1981) Confounding: essence and detection. Am J Epidemiol, 114, 593–603.
Miller, C. J., Klugman, J. Berv, D. A., Rasenquist, K. J. and Ghaemi, S. N. (2004) Sensitivity and specificity of the Mood Disorder Questionnaire for detecting bipolar disorder. J Affect Disord, 81, 161–71.
Mills, C. (1963) Power, Politics, and People. New York: Oxford University Press.
Moncrieff, J., Wessely, S. and Hardy, R. (1998) Meta-analysis of trials comparing antidepressants with active placebos. Br J Psychiatry, 172, 227–31; discussion 232–4.
Moynihan, R. (2008) Key opinion leaders: independent experts or drug representatives in disguise? BMJ, 336, 1402–3.
Moynihan, R., Heath, I. and Henry, D. (2002) Selling sickness: the pharmaceutical industry and disease mongering. BMJ, 324, 886–91.
National Institute of Health (1979) The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research. Washington DC: US Government Printing Office.
Nemeroff, C. B., Evans, D. L., Gyulai, L., et al. (2001) Double-blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depression. Am J Psychiatry, 158, 906–12.
Olmsted, J. (1952) Claude Bernard and the Experimental Method in Medicine. London: H. Schuman.
Osler, W. (1932) Aequanimitas with other Addresses. Philadelphia: P. Blakiston's Son and Co.
Pande, A. C., Crockatt, J. G., Janney, C. A., Werth, J. L. and Tsaroucha, G. (2000) Gabapentin in bipolar disorder: a placebo-controlled trial of adjunctive therapy. Gabapentin Bipolar Disorder Study Group. Bipolar Disord, 2, 249–55.
Parascandola, M. (2004) Skepticism, statistical methods, and the cigarette: a historical analysis of a methodological debate. Perspect Biol Med, 47, 244–61.
Parker, G., Tully, L., Olley, A. and Hadzi-Pavlovic, D. (2006) SSRIs as mood stabilizers for Bipolar II Disorder? A proof of concept study. J Affect Disord, 92, 205–14.
Patsopoulos, N. A., Ioannidis, J. P. and Analatos, A. A. (2006) Origin and funding of the most frequently cited papers in medicine: database analysis. BMJ, 332, 1061–4.
Peirce, C. (1958) P. Weiner, Ed., Selected Writings. New York: Dover Publications.
Phelps, J. R. and Ghaemi, S. N. (2006) Improving the diagnosis of bipolar disorder: predictive value of screening tests. J Affect Disord, 92, 141–8.
Poe, E. (1845) The system of Dr. Tarr and Prof. Fether. Graham's Magazine, Vol XXVIII, No. 5, p. 194.
Pollard, P., & Richardson, J. T. E. (1987) On the probability of making Type I errors. Psychol Bull, 102, 159–163.
Popper, K. (1959) The Logic of Scientific Discovery. New York: Basic Books.
Porter, R. (1997) The Greatest Benefit to Mankind: A Medical History of Humanity. New York: Norton.
Posternak, M. A. and Zimmerman, M. (2003) How accurate are patients in reporting their antidepressant treatment history? J Affect Disord, 75, 115–24.
Prentice, R. L., Langer, R. D., Stefanick, M. L., et al. (2006) Combined analysis of Women's Health Initiative observational and clinical trial data on postmenopausal hormone treatment and cardiovascular disease. Am J Epidemiol, 163, 589–99.
Roberts, L. W., Warner, T. D., Brody, J. L., et al. (2002) Patient and psychiatrist ratings of hypothetical schizophrenia research protocols: assessment of harm potential and factors influencing participation decisions. Am J Psychiatry, 159, 573–84.
Robin, E. D. (1985) The cult of the Swan-Ganz catheter. Overuse and abuse of pulmonary flow catheters. Ann Intern Med, 103, 445–9.
Robins, E. and Guze, S. B. (1970) Establishment of diagnostic validity in psychiatric illness: its application to schizophrenia. Am J Psychiatry, 126, 983–7.
Ross, J. S., Hill, K. P., Egilman, D. S. and Krumholz, H. M. (2008) Guest authorship and ghostwriting in publications related to rofecoxib: a case study of industry documents from rofecoxib litigation. JAMA, 299, 1800–12.
Rothman, K. J. and Greenland, S. (1998) Modern Epidemiology. Philadelphia: Lippincott-Raven.
Sachs, G. S., Grossman, F., Ghaemi, S. N., Okamoto, A. and Bowden, C. L. (2002) Combination of a mood stabilizer with risperidone or haloperidol for treatment of acute mania: a double-blind, placebo-controlled comparison of efficacy and safety. Am J Psychiatry, 159, 1146–54.
Sachs, G. S., Nierenberg, A. A., Calabrese, J. R., et al. (2007) Effectiveness of adjunctive antidepressant treatment for bipolar depression. N Engl J Med, 356, 1711–22.
Sackett, D., Strauss, S., Richardson, W., Rosenberg, W. and Haynes, R. (2000) Evidence Based Medicine. London: Churchill Livingstone.
Salsburg, D. (2001) The Lady Tasting Tea: How Statistics Revolutionized Science in the Twentieth century. New York: W. H. Freeman and Company.
Shepherd, M. (1993) The placebo: from specificity to the non-specific and back. Psychol Med, 23, 569–78.
Silberman, E. K. and Snyderman, D. A. (1997) Research without external funding in North American psychiatry. Am J Psychiatry, 154, 1159–60.
Silverman, W. (1998) Where's the Evidence? Debates in Modern Medicine. New York: Oxford University Press.
Sleight, P. (2000) Debate: subgroup analyses in clinical trials: fun to look at – but don't believe them! Curr Control Trials Cardiovasc Med, 1, 25–7.
Smith, G. and Pell, J. (2003) Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomized controlled trials. BMJ, 327, 1459–61.
Soldani, F., Ghaemi, S. N. and Baldessarini, R. (2005) Research methods in psychiatric treatment studies. Critique and proposals. Acta Psychiatr Scand, 112, 1–3.
Sonis, J. (2004) Mortality and poststroke depression. Am J Psychiatry, 161, 1506–7; author reply 1507–8.
Sox, H. C. and Rennie, D. (2006) Research misconduct, retraction, and cleansing the medical literature: lessons from the Poehlman case. Ann Intern Med, 144, 609–13.
Sprock, J. (1988) Classification of schizoaffective disorder. Compr Psychiatry, 29, 55–71.
Stahl, S. M. (2002) Antipsychotic polypharmacy: evidence based or eminence based? Acta Psychiatr Scand, 106, 321–2.
Stahl, S. M. (2005) Essential Psychopharmacology. Cambridge, UK: Cambridge University Press.
Stigler, S. (1986) The History of Statistics: The Measurement of Uncertainty Before 1900. Cambridge, MA: Harvard University Press.
Tatsioni, A., Bonitsis, N. G. and Ioannidis, J. P. (2007) Persistence of contradicted claims in the literature. JAMA, 298, 2517–26.
Tohen, M., Vieta, E., Calabrese, J., et al. (2003) Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression. Arch Gen Psychiatry, 60, 1079–88.
Tohen, M., Chengappa, K. N., Suppes, T., et al. (2004) Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone. Br J Psychiatry, 184, 337–45.
Turner, E. H., Matthews, A. M., Linardatos, E., Tell, R. A. and Rosenthal, R. (2008) Selective publication of antidepressant trials and its influence on apparent efficacy. N Engl J Med, 358, 252–60.
Wang, R., Lagakos, S. W., Ware, J. H., Hunter, D. J. and Drazen, J. M. (2007) Statistics in medicine–reporting of subgroup analyses in clinical trials. N Engl J Med, 357, 2189–94.
Yastrubetskaya, O., Chiu, E. and O’Connell, S. (1997) Is good clinical research practice for clinical trials good clinical practice? Int J Geriatr Psychiatry, 12, 227–31.
Zimmerman, M., Mattia, J. I. and Posternak, M. A. (2002) Are subjects in pharmacological treatment trials of depression representative of patients in routine clinical practice? Am J Psychiatry, 159, 469–73.


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