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  3. Flow Cytometry Data Analysis
  • Cited by 29
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    • Publisher:
      Cambridge University Press
      Publication date:
      October 2009
      November 1992
      ISBN:
      9780511600357
      9780521415453
      9780521019705
      DOI:
      https://doi.org/10.1017/CBO9780511600357
      Dimensions:
      (228 x 152 mm)
      Weight & Pages:
      0.565kg, 300 Pages
      Dimensions:
      (228 x 152 mm)
      Weight & Pages:
      0.483kg, 300 Pages
      • Subjects:
      Life Sciences, Pathology and Laboratory Science, Medicine, Cell Biology and Developmental Biology
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    • Selected: Digital
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    Subjects:
    Life Sciences, Pathology and Laboratory Science, Medicine, Cell Biology and Developmental Biology
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    Book description

    Flow cytometry is now well established in research laboratories and is gaining increasing use in clinical medicine and pathology. The technique enables multiple simultaneous light scatter and fluorescence measurements to be made at the individual cell level at very rapid rates and results in very large quantities of data being collected. Data, however, is just a series of numbers which have to be converted to information which, in turn, must be shown to have meaning. This is the most important single aspect of flow cytometry but it has received relatively little attention. One of the frequently voiced advantages of the technology is that it produces 'good statistics' because large numbers of cells have been analysed. However, it is not very often that confidence limits are placed on results, hence the reader has little or no feel for the inherent variability in the information produced. This book covers very basic number handling techniques, regression analysis, probability functions, statistical tests and methods of analysing dynamic processes. All those who use flow cytometry in their research will find this book an invaluable guide to interpreting the data produced by flow cytometers.

    Reviews

    "I recommend this book as an introduction to statistics for the mathematically intimidated and as a gateway into flow cytometry for the mathematically sophisticated.....the book should prove useful." Cancer Bulletin

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