Magnesium in the Central Nervous System

doi:10.1017/UPO9780987073051

This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesium's involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior.

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Contents

Frontmatter
pp i-iv
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List of Contributors
pp v-vii
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Preface
pp viii-viii
- By Robert Vink, The University of Adelaide, Adelaide, South Australia, Australia, Mihai Nechifor, University of Medicine and Pharmacy, lasi, Romania
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Contents
pp ix-x
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Section 1 - Magnesium in Normal Brain
pp 1-2
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Chapter 1 - Free magnesium concentration in human brain
pp 3-12
- By Stefano Lotti, Dipartimento di Medicina Interna, dell'Invecchiamento e Malattie Nefrologiche, Università di Bologna, Italy; Istituto Nazionale di Biostrutture e Biosistemi, Roma, Emil Malucelli, Dipartimento di Medicina Interna, dell'Invecchiamento e Malattie Nefrologiche', Università di Bologna, Italy
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Chapter 2 - Intracellular magnesium homeostasis
pp 13-58
- By Andrea M.P. Romani, Department of Physiology and Biophysics, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA
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Chapter 3 - Magnesium transport across the blood-brain barriers
pp 59-74
- By Mounir N. Ghabriel, Discipline of Anatomy and Pathology & Adelaide Centre for Neuroscience Research, School of Medical Sciences, The University of Adelaide, Adelaide, South Australia 5005, Australia.; mounir.ghabriel@adelaide.edu.au, Robert Vink, Discipline of Anatomy and Pathology & Adelaide Centre for Neuroscience Research, School of Medical Sciences, The University of Adelaide, Adelaide, South Australia 5005, Australia
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Chapter 4 - Intracellular free Mg2+ and MgATP2− in coordinate control of protein synthesis and cell proliferation
pp 75-84
- By Harry Rubin, Department of Molecular and Cell Biology, Life Sciences Addition, University of California, Berkeley, CA 94720-3200, USA
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Chapter 5 - Magnesium and the Yin-Yang interplay in apoptosis
pp 85-98
- By Valentina Trapani, Istituto di Patologia Generale e Centro di Ricerche Oncologiche Giovanni XXIII, Università Cattolica del Sacro Cuore, Rome, Italy, Lucia Mastrototaro, Istituto di Patologia Generale e Centro di Ricerche Oncologiche Giovanni XXIII, Università Cattolica del Sacro Cuore, Rome, Italy, Federica I. Wolf, Istituto di Patologia Generale e Centro di Ricerche Oncologiche Giovanni XXIII, Università Cattolica del Sacro Cuore, Rome, Italy
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Chapter 6 - Brain magnesium homeostasis as a target for reducing cognitive ageing
pp 99-112
- By Jean-Marie Billard, Université Paris Descartes, Faculté de Médcine René Descartes, Centre de Psychiatrie et Neurosciences, UMR 894, Paris, France
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Section 2 - Magnesium in Neurological Diseases
pp 113-114
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Chapter 7 - The role of magnesium therapy in learning and memory
pp 115-124
- By Michael R. Hoane, Restorative Neuroscience Laboratory, Brain and Cognitive Science Program, Department of Psychology, Southern Illinois University,Carbondale, IL, USA
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Chapter 8 - The role of magnesium in headache and migraine
pp 125-134
- By Lisa A. Yablon, The New York Headache Center, 30 East 76th Street, New York, NY 10021, USA, Alexander Mauskop, The New York Headache Center, 30 East 76th Street, New York, NY 10021, USA
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Chapter 9 - Magnesium in edema and blood-brain barrier disruption
pp 135-144
- By Mehmet Kaya, Departments of Physiology and of Histology and Embryology, Istanbul Faculty of Medicine, Istanbul University, Capa 34093 Istanbul, Turkey, Bulent Ahishali, Departments of Physiology and of Histology and Embryology, Istanbul Faculty of Medicine, Istanbul University, Capa 34093 Istanbul, Turkey
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Chapter 10 - Magnesium and hearing loss
pp 145-156
- By Isabelle Sendowski, Institut de Recherche Biomédicale des Armées, Antenne de la Tronche, La Tronche, France, Xavier Holy, Institut de Recherche Biomédicale des Armées, Antenne de Brétigny, Brétigny-sur-Orge, France, Florent Raffin, Institut de Recherche Biomédicale des Armées, Antenne de la Tronche, La Tronche, France, Yves Cazals, UMR6231, Université Paul Cézanne, Marseille, France
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Chapter 11 - The role of magnesium in pain
pp 157-166
- By Hyo-Seok Na, Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea, Jung-Hee Ryu, Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea, Sang-Hwan Do, Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea
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Chapter 12 - The role of magnesium in traumatic CNS injury
pp 167-180
- By Naomi L. Cook, Discipline of Anatomy and Pathology & Adelaide Centre for Neuroscience Research, School of Medical Sciences, The University of Adelaide, Adelaide, South Australia 5005, Australia, Frances Corrigan, Discipline of Anatomy and Pathology & Adelaide Centre for Neuroscience Research, School of Medical Sciences, The University of Adelaide, Adelaide, South Australia 5005, Australia, Corinna van den Heuvel, Discipline of Anatomy and Pathology & Adelaide Centre for Neuroscience Research, School of Medical Sciences, The University of Adelaide, Adelaide, South Australia 5005, Australia
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Chapter 13 - The use of magnesium in experimental cerebral ischaemia
pp 181-192
- By Bruno P. Meloni, Centre for Neuromuscular and Neurological Disorders, University of Western Australia, and the Australian Neuromuscular Research Institute, Department of Neurosurgery, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia, Kym Campbell, Centre for Neuromuscular and Neurological Disorders, University of Western Australia, and the Australian Neuromuscular Research Institute, Department of Neurosurgery, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia, Neville W. Knuckey, Centre for Neuromuscular and Neurological Disorders, University of Western Australia, and the Australian Neuromuscular Research Institute, Department of Neurosurgery, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia
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Chapter 14 - Magnesium in subarachnoid hemorrhage
pp 193-204
- By Walter M. van den Bergh, Department of Intensive Care, Academic Medical Center, Amsterdam, The Netherlands
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Chapter 15 - Magnesium in clinical stroke
pp 205-216
- By Jeffrey L. Saver, UCLA Stroke Center and Department of Neurology, University of California, Los Angeles, CA 90095, USA, Sidney Starkman, UCLA Stroke Center and Department of Neurology, University of California, Los Angeles, CA 90095, USA
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Chapter 16 - Magnesium in cancer: more questions than answers
pp 217-228
- By Marzia Leidi, Università di Milano, Dipartimento di Scienze Cliniche Luigi Sacco, 20157 Milano, Italy, Federica I. Wolf, Università Cattolica del Sacro Cuore, Istituto di Patologia generale e Centro di Ricerche Oncologiche Giovanni XXIII, Facoltà di Medicina “A. Gemelli”, 00168 Roma, Italy, Jeanette A.M. Maier, Università di Milano, Dipartimento di Scienze Cliniche Luigi Sacco, 20157 Milano, Italy
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Chapter 17 - Magnesium in Parkinson's disease: an update in clinical and basic aspects
pp 229-236
- By Kiyomitsu Oyanagi, Department of Brain Disease Research, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan, Tomoyo Hashimot, Department of Brain Disease Research, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan
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Section 3 - Involvement of Magnesium in Psychiatric Diseases
pp 237-238
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Chapter 18 - Magnesium and Alzheimer's disease
pp 239-250
- By Dehua Chui, Neuroscience Research Institute & Department of Neurobiology, Key Laboratory for Neuroscience, Ministry of Education & Ministry of Public Health, Health Science Center, Peking University, Beijing 100191, China, Zheng Chen, Department of Psychiatry & Institute for Geriatric Clinic and Rehabilitation, Beijing Geriatric Hospital, Beijing 100095, China, Jia Yu, Department of Psychiatry & Institute for Geriatric Clinic and Rehabilitation, Beijing Geriatric Hospital, Beijing 100095, China, Honglin Zhang, Department of Psychiatry & Institute for Geriatric Clinic and Rehabilitation, Beijing Geriatric Hospital, Beijing 100095, China, Weishan Wang, Department of Psychiatry & Institute for Geriatric Clinic and Rehabilitation, Beijing Geriatric Hospital, Beijing 100095, China, Yuetao Song, Department of Psychiatry & Institute for Geriatric Clinic and Rehabilitation, Beijing Geriatric Hospital, Beijing 100095, China, Huan Yang, Neuroscience Research Institute & Department of Neurobiology, Key Laboratory for Neuroscience, Ministry of Education & Ministry of Public Health, Health Science Center, Peking University, Beijing 100191, China, Yi Liu, Neuroscience Research Institute & Department of Neurobiology, Key Laboratory for Neuroscience, Ministry of Education & Ministry of Public Health, Health Science Center, Peking University, Beijing 100191, China
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Chapter 19 - Magnesium and stress
pp 251-268
- By Magdalena D. Cuciureanu, Department of Pharmacology, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, 700115, Romania, Robert Vink, Centre for Neuroscience Research, School of Medical Sciences, The University of Adelaide, South Australia 5005, Australia
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Chapter 20 - Magnesium in neuroses
pp 269-282
- By Victoria Papadopol, Regional Centre of Public Health, Iasi, Romania, Mihai Nechifor, Department of Pharmacology, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Romania
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Chapter 21 - Magnesium, hyperactivity and autism in children
pp 283-302
- By Marianne Mousain-Bosc, Ecole de l'ADN, Museum d'Histoire Naturelle de Nîmes, 19, Grand'rue, 30000 Nimes, France, Christian Siatka, Ecole de l'ADN, Museum d'Histoire Naturelle de Nîmes, 19, Grand'rue, 30000 Nimes, France, Jean-Pierre Bali, Université Montpellier I, 34000 Montpellier, France
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Chapter 22 - Magnesium in psychoses (schizophrenia, bipolar disorder)
pp 303-312
- By Mihai Nechifor, Department of Pharmacology, “Gr.T.Popa” University of Medicine and Pharmacy, Iasi, Romania
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Chapter 23 - Magnesium and major depression
pp 313-332
- By George A. Eby III, George Eby Research Institute, 14909-C 2109 Paramount Avenue, Austin, Texas 78704, USA.; george.eby “at” george-eby-research.com, Karen L. Eby, George Eby Research Institute, 14909-C 2109 Paramount Avenue, Austin, Texas 78704, USA, Harald Murck, Clinic of Psychiatry and Psychotherapy, University of Marburg, 35043 Marburg, Germany
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