Memory in Neurodegenerative Disease: Biological, Cognitive, and Clinical Perspectives

doi:10.1017/CBO9780511544378

This book is the first to review in depth the neurobiological and clinical characteristics of memory and its disorders in neurodegenerative disease. It presents current information about memory disorders in Alzheimer's, Huntington's and Parkinson's diseases and in other neurological conditions such as progressive supranuclear palsy, Creutzfeld–Jacob disease and HIV-associated dementia. The contributors are among the most distinguished working in this field. They present the neuroanatomical and neurochemical basis of memory disorders in neurodegenerative disease, and review the contribution of neuroradiology and neuropathology to the understanding of memory and amnesia. Diagnosis, assessment and treatment issues are discussed, as are ethical and legal considerations and topics of emerging interest such as the early detection of dementia. Bringing together biological, cognitive and clinical information, this book will be an essential reference for clinicians and neuroscientists. It serves as an authoritative and up-to-date overview of the dementias and the prospects for treating them.

"...scientists, medical doctors, and clinicians alike will find this volume most valuable, instructive, and thought-provoking." The Canadian Journal of Neurological Sciences

"It provides the reader with a comprehensive source of information on memory in neurodegenerative disorders. It is noteworthy for its inclusive rather than exclusive nature, as it offers perpectives from a variety of disciplines...offers a great deal to persons interested in neurodegenrative disorders where memory is significantly affected, particularly those who are first delving into the area or are looking for a comprehensive source of information." Journal of the Int'l Neuropsychologiycal Soc Nov 2000

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Contents

Frontmatter
pp i-iv
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Contents
pp v-viii
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List of contributors
pp ix-xii
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Preface
pp xiii-xiii
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PART I - Biological perspectives
pp 1-2
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1 - Nonhuman primate models of memory dysfunction in neurodegenerative disease: contributions from comparative neuropsychology
pp 3-20
- By Marlene Oscar-Berman, Fiona Bardenhagen
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2 - Nonprimate animal models of motor and cognitive dysfunction associated with Huntington's disease
pp 21-35
- By Raymond P. Kesner, J. Vincent Filoteo
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3 - Neuropathology and memory dysfunction in neurodegenerative disease
pp 36-86
- By Julie A. Testa, Roger A. Brumback, Tai-Kyoung Baik, Richard W. Leech, Thomas C. Cannon
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4 - Neurochemical aspects of memory dysfunction in neurodegenerative disease
pp 87-99
- By Edison Miyawaki, William C. Koller
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5 - Structural neuroimaging correlates of memory dysfunction in neurodegenerative disease
pp 100-127
- By Edith V. Sullivan, Deborah A. Cahn, Rosemary Fama, Paula K. Shear
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6 - Functional neuroimaging correlates of memory dysfunction in neurodegenerative disease
pp 128-139
- By Stanley Berent, Bruno Giordani
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7 - The biology of neurodegenerative disease
pp 140-154
- By Hans J. Markowitsch
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PART II - Cognitive perspectives
pp 155-156
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8 - The role of executive deficits in memory disorders in neurodegenerative disease
pp 157-171
- By Adrian M. Owen, Barbara J. Sahakian, Trevor W. Robbins
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9 - Prospective memory in aging and neurodegenerative disease
pp 172-183
- By Robert G. Knight
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10 - Remote memory in neurodegenerative disease
pp 184-196
- By Robert H. Paul, Joni R. Graber, David C. Bowlby, Julie A. Testa, Michael J. Harnish, William W. Beatty
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11 - Semantic memory in neurodegenerative disease
pp 197-209
- By Joseph W. Fink, Christopher Randolph
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12 - Nondeclarative memory in neurodegenerative disease
pp 210-225
- By David P. Salmon, Tara T. Lineweaver, William C. Heindel
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13 - Memory in neurodegenerative disease: what has been learned about the organization of memory?
pp 226-240
- By Andrew R. Mayes
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PART III - Clinical perspectives
pp 241-242
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14 - Biological and psychosocial risk factors for dementia and memory loss
pp 243-254
- By Diane M. Jacobs, Peter Schofield
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15 - Cross-cultural issues in the neuropsychological assessment of neurodegenerative disease
pp 255-261
- By Andreas U. Monsch, Kirsten I. Taylor, Mark W. Bondi
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16 - Psychometric issues in the clinical assessment of memory in aging and neurodegenerative disease
pp 262-277
- By Anthony M. Paolo
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17 - The role of memory assessment in the preclinical detection of dementia
pp 278-289
- By Mark W. Bondi, Andreas U. Monsch
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18 - Clinical differentiation of memory disorders in neurodegenerative disease
pp 290-313
- By Kathleen A. Welsh-Bohmer, Paula K. Ogrocki
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19 - The impact of depression on memory in neurodegenerative disease
pp 314-337
- By Julie A. Fields, Suzanne Norman, Kristy A. Straits-Tröster, Alexander I. Tröster
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20 - Preserved cognitive skills in neurodegenerative disease
pp 338-348
- By Joni R. Graber, Robert H. Paul, Julie A. Testa, David C. Bowlby, Michael J. Harnish, William W. Beatty
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21 - Drug treatment of cognitive impairment in neurodegenerative disease: rationale, current experience and expectations for the future
pp 349-361
- By Louis T. Giron, Jr, William C. Koller
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22 - Surgical interventions in neurodegenerative disease: impact on memory and cognition
pp 362-376
- By Steven B. Wilkinson, Alexander I. Tröster
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23 - Memory dysfunction in neurodegenerative disease: ethical and legal issues
pp 377-389
- By Martin D. Zehr
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Memory in Neurodegenerative Disease

Biological, Cognitive, and Clinical Perspectives

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