Monoclonal antibodies are one of the most exciting developments in biotechnology in recent years; this book provides a comprehensive description of principles, methodologies and applications of this powerful technology to modern science and industry. The immune system of the body, in particular the role of antibodies, is described; and details provided on the isolation of antibody-producing cells, how hybridomas are formed and maintained in culture such that the required antibody can be produced to a very high degree of purity. The material is presented in such a way that students, researchers and managers in research and development will be able to make choices as to which are the most suitable techniques for their particular requirements. The text is comprehensively referenced and, in short, the book is a necessary resource for all those who have the need to be involved in the production of monoclonal antibodies from hybridoma cells in culture.

"...the book provides useful information for hydridoma users." Quarterly Review of Biology

"...comprehensive text...the authors strike a good balance between general and technical information. Each chapter explains theories and rationales and provides very detailed methodologies that appear to be directly useful at the lab bench...an important compendium if you want to know how to make monoclonal antibodies..." BioPharm

"This book is really of fundamental importance since it brings a lot of fundamental information of theoretical and practical aspects on the biotechnology of monoclonal antibodies...Such a book should find entrance in all laboratories, without exception, since it is the first one giving such a great and deep insight in this very highly modern problem." Cellular and Molecular Biology