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  1. Home
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  3. Neuronal Substrates of Sleep and Epilepsy
  • Cited by 88
Publisher:
Cambridge University Press
Online publication date:
September 2009
Print publication year:
2003
Online ISBN:
9780511541711
DOI:
https://doi.org/10.1017/CBO9780511541711
Subjects:
Life Sciences, Neurology and Clinical Neuroscience, Medicine, Neurosciences
Information

Book description

Different states of vigilance and various paroxysmal disorders that occur during slow-wave sleep can have the same neural bases. Conventional wisdom holds that sleep is a resting state of the brain, with negligible activity of cortical neurons. Here, the author brings new evidence favoring the idea that during this behavioral state memory traces acquired during waking are consolidated. The author focuses on the coalescence of different sleep rhythms in interacting corticothalamic networks and on three types of paroxysmal disorders, namely spike-wave seizures as in absence epilepsy, Lennox-Gastaut seizures, and temporal-lobe epilepsy. Many physiological correlates of waking and sleep states as well as diverse types of epileptic seizures are also discussed. The book has copious illustrations with examples from in vivo, in vitro and 'in computo' studies, the majority coming from the author's own laboratory. Neuronal Substrates of Sleep and Epilepsy is essential reading for neuroscientists and clinical researchers.

Reviews

‘… invaluable to neuroscientists and clinical researchers of sleep. It will also prove useful to neurophysiologists and neurologists who have an interest in the biological basis of sleep and seizure disorders.’

Source: The Lancet

'A remarkable tour de force from a master of integrative neurophysiology.'

Source: Neuroscience

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