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Predictive Toxicology in Drug Safety
  • Cited by 4
  • Edited by Jinghai J. Xu, Merck Research Laboratory, New Jersey, Laszlo Urban, Novartis Institutes for Biomedical Research, Massachusetts
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Book description

According to the Institute of Medicine (IOM) and U.S. Food and Drug Administration (FDA), 'developing new scientific approaches to detecting, understanding, predicting and preventing adverse events' was a critical path to the future of drug safety. This book brings together a collection of state-of-the-art chapters, written by experts in the drug safety field. It provides information on the present knowledge of drug side effects and their mitigation strategy during drug discovery, gives guidance for risk assessment and promotes evidence-based toxicology. Each specific area of toxicology relevant for drug discovery is discussed in detail, including theory, experimental approaches and data interpretation supported by comprehensive up-to-date references. Many chapters provide fascinating case studies, which are of general interest for those who have basic science training and are interested in how chemicals interact with the human body.

Reviews

"... an in-depth reference in the field of predictive toxicology, Inclusion of useful case studies, description of experimental methods and models, graphical analysis and presentations, with ample references at the end of each chapter are useful, sometimes unique features of this book. It will be of great interest not only to academics but also o the scholars and researchers working in the field of toxicology..."
Shubhini A. Saraf, Roshan K. Sahu for Drug and Alcohol Review

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