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Computer-assisted cognitive remediation in adolescents with psychosis or at risk for psychosis: a 6-month follow-up

  • Sébastien Urben (a1), Sandrine Pihet (a1), Laure Jaugey (a2), Olivier Halfon (a3) and Laurent Holzer (a2)...
Extract

Urben S, Pihet S, Jaugey L, Halfon O, Holzer L. Computer-assisted cognitive remediation in adolescents with psychosis or at risk for psychosis: a 6-month follow-up.

Objective: To investigate short-term outcomes of a computer-assisted cognitive remediation (CACR) for adolescents with psychotic disorders or at high risk for psychosis.

Method: Cognitive abilities and clinical status were assessed at baseline (N = 32) and at 6-month follow-up (N = 22) after enrolment in either a CACR (treatment group) or a computer games (control group) program (8 weeks).

Results: With regard to the cognitive abilities, no amelioration was found in the control group while, in the CACR group, significant improvements in inhibition (p = 0.040) and reasoning (p = 0.005) were observed. Furthermore, symptom severity decreased significantly in the control group (p = 0.046) and marginally in the CACR group (p = 0.088). Improvements in cognitive abilities were not associated with symptoms' amelioration. Finally, increase in reasoning abilities was related to the median effective work time in sessions of CACR (R = 0.64, p = 0.024).

Conclusion: At follow-up, enhanced cognitive abilities (reasoning and inhibition), which are necessary for executing higher-order goals or adapting behaviour to the ever-changing environment, were reported in adolescents participants of the CACR. Thus, further studies are needed to confirm and extend these interesting results.

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Corresponding author
Sébastien Urben, Research Unit, University Service of Child and Adolescent Psychiatry, Route du Bugnon 25A, 1011 Lausanne, Switzerland. Tel: +41 21 3147493; Fax: +41 21 3147481; E-mail: Sebastien.Urben@chuv.ch
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