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The course of bipolar disorder

  • Kate E. A. Saunders (a1) and Guy M. Goodwin (a1)
Summary

Bipolar disorder is arguably a pivotal diagnosis in adult psychiatry bounded by schizophrenia on one side and unipolar depression on the other. It represents a wide spectrum of disorders, all sharing common features of elated and depressed mood. The early descriptions of symptom-free euthymia have long been dismissed and the chronic and enduring deficits associated with the disorder are beginning to be better understood. We review the current literature with regard to the course of the disorder, factors that may influence prognosis and common comorbidities.

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Corresponding author
Professor Guy M. Goodwin, University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK. Email: guy.goodwin@psych.ox.ac.uk
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Declaration of Interest

G.M.G. has held grants from Sanofi-aventis and Servier, received honoraria for speaking or chairing educational meetings from AstraZeneca, Bristol-Meyers Squibb, Eisai, Lundbeck, Sanofi-Aventis, and Servier, and advised AstraZeneca, Bristol-Meyers Squibb, Hoffman-Laroche, Janssen-Cilag, Lilly, Lundbeck, P1vital, Sanofi-aventis, Servier and Wyeth. He holds shares in P1vital and acted as expert witness for Lilly and Servier.

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References
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The course of bipolar disorder

  • Kate E. A. Saunders (a1) and Guy M. Goodwin (a1)
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