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Neurosurgery for mental disorder

  • David Christmas, Colin Morrison, Muftah S. Eljamel and Keith Matthews
Abstract

The authors review contemporary indications for neurosurgical interventions in the management of chronic and refractory mental disorder, the procedures involved, their efficacy and known adverse effects. These data are presented within the context of a brief historical overview of the use of neurosurgery for mental disorder. In addition to a consideration of neurosurgical procedures that rely on the creation of putative therapeutic lesions, we also review two novel, non-destructive neurosurgical electrostimulation treatments that may represent viable alternatives to conventional ablative neurosurgery: vagus nerve stimulation and deep brain stimulation.

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References
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Baer, L., Rauch, S. L., Ballantine, H. T. Jr. et al (1995) Cingulotomy for intractable obsessive–compulsive disorder. Prospective long-term follow-up of 18 patients. Archives of General Psychiatry, 52, 384392.
Ballantine, H. T. Jr., Bouckoms, A. J., Thomas, E. K. et al (1987) Treatment of psychiatric illness by stereotactic cingulotomy Biological Psychiatry, 22, 807819.
Barraclough, B. M. & Mitchell-Heggs, N. A. (1978) Use of neurosurgery for psychological disorder in British Isles during 1974–6. BMJ, 2, 15911593.
Bebbington, P. E. (1998) Epidemiology of obsessive-compulsive disorder. British Journal of Psychiatry, 173 (suppl. 35), 26.
Bejjani, B. P., Damier, P., Arnulf, I. et al (1999) Transient acute depression induced by high-frequency deep-brain stimulation. New England Journal of Medicine, 340, 14761480.
Berney, A., Vingerhoets, F., Perrin, A. et al (2002) Effect on mood of subthalamic deep brain stimulation for Parkinson's disease: a consecutive series of 24 patients. Neurology, 59, 14271429.
Breiter, H. C., Rauch, S. L., Kwong, K. K. et al (1996) Functional magnetic resonance imaging of symptom provocation in obsessive-compulsive disorder. Archives of General Psychiatry, 53, 595606.
Bridges, P. K., Bartlett, J. R., Hale, A. S. et al (1994) Psychosurgery: stereotactic subcaudate tractotomy. An indispensable treatment. British Journal of Psychiatry, 165, 599611; discussion 612–593.
CRAG Working Group on Mental Illness (1996) Neurosurgery for Mental Disorder. Edinburgh: CRAG.
Dougherty, D. D., Baer, L., Cosgrove, G. R. et al (2002) Prospective long-term follow-up of 44 patients who received cingulotomy for treatment-refractory obsessive-compulsive disorder. American Journal of Psychiatry, 159, 269275.
Gabriëls, L. A., Cosyns, P. R., Meyerson, B. A. et al (2003) Long-term electrical capsular stimulation in patients with obsessive-compulsive disorder. Neurosurgery, 52, 12631274.
Goktepe, E. O., Young, L. B. & Bridges, P. K. (1975) A further review of the results of stereotactic subcaudate tractotomy. British Journal of Psychiatry, 126, 270280.
Greenberg, P. E., Stiglin, L. E., Finkelstein, S. N. et al (1993) Depression: a neglected major illness. Journal of Clinical Psychiatry, 54, 419424.
Greenberg, P. E., Sisitsky, T., Kessler, R. C. et al (1999) The economic burden of anxiety disorders in the 1990s. Journal of Clinical Psychiatry, 60, 427435.
Guy, W. (1976) ECDEU Assessment Manual for Psychopharmacology. Revised DHEW Publ. (ADM). Rockville, MD: National Institute for Mental Health.
Judd, L. L. (1997) The clinical course of unipolar major depressive disorders. Archives of General Psychiatry, 54, 989991.
Kartsounis, L. D., Poynton, A., Bridges, P. K. et al (1991) Neuropsychological correlates of stereotactic subcaudate tractotomy. A prospective study. Brain, 114, 26572673.
Kelly, D. (1985) Neurosurgical treatment of psychiatric disorders. In Recent Advances in Clinical Psychiatry (ed. Granville-Grossman, K.) pp. 227261. Edinburgh & New York: Churchill Livingstone.
Kessler, R. C. P., McGonagle, K. A. P., Zhao, S. P. et al (1994) Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Archives of General Psychiatry, 51, 819.
Kim, C.H., Chang, J. W., Koo, M.S. et al (2003) Anterior cingulotomy for refractory obsessive compulsive disorder. Acta Psychiatrica Scandinavica, 107, 283290.
Knight, G. (1965) Stereotactic tractotomy in the surgical treatment of mental illness. Journal of Neurology, Neurosurgery, and Psychiatry, 28, 304310.
Kulisevsky, J., Berthier, M. L., Gironell, A. et al (2002) Mania following deep brain stimulation for Parkinson's disease. Neurology, 59, 14211424.
Kumar, R., Krack, P. & Pollak, P. (1999) Transient acute depression induced by high-frequency deep-brain stimulation. New England Journal of Medicine, 341, 10031004; author reply 1004.
Lindeman, S., Hamalainen, J., Isometsa, E. et al (2000) The 12-month prevalence and risk factors for major depressive episode in Finland: representative sample of 5993 adults. Acta Psychiatrica Scandinavica, 102, 178184.
Loddenkemper, T., Pan, A., Neme, S. et al (2001) Deep brain stimulation in epilepsy. Journal of Clinical Neurophysiology, 18, 514532.
Lovett, L. M. & Shaw, D. M. (1987) Outcome in bipolar affective disorder after stereotactic tractotomy. British Journal of Psychiatry, 151, 113116.
Mallet, L., Mesnage, V., Houeto, J. L. et al (2002) Compulsions, Parkinson's disease and stimulation. Lancet, 360, 13021304.
Marangell, L. B., Rush, A. J., George, M. S. et al (2002) Vagus nerve stimulation (VNS) for major depressive episodes: one year outcomes. Biological Psychiatry, 51, 280287.
Matthews, K. & Eljamel, M. S. (2003) Status of neurosurgery for mental disorder in Scotland. Selective literature review and overview of current clinical activity. British Journal of Psychiatry, 182, 404411.
Mitchell-Heggs, N., Kelly, D. & Richardson, A. (1976) Stereotactic limbic leucotomy A follow-up at 16 months. British Journal of Psychiatry, 128, 226240.
Montoya, A., Weiss, A. P., Price, B. H. et al (2002) Magnetic resonance imaging-guided stereotactic limbic leukotomy for treatment of intractable psychiatric disease. Neurosurgery, 50, 10431049; discussion 1049–1052.
Nuttin, B., Cosyns, P., Demeulemeester, H. et al (1999) Electrical stimulation in anterior limbs of internal capsules in patients with obsessive-compulsive disorder. Lancet, 354, 1526.
Poynton, A., Bridges, P. K. & Bartlett, J. R. (1988) Resistant bipolar affective disorder treated by stereotactic subcaudate tractotomy. British Journal of Psychiatry, 152, 354358.
Regier, D. A., Farmer, M. E., Rae, D. S. et al (1993) One-month prevalence of mental disorders in the United States and sociodemographic characteristics: the Epidemiologic Catchment Area study. Acta Psychiatrica Scandinavica, 88, 3547.
Royal College of Psychiatrists (2000) Neurosurgery for Mental Disorder. Report from the Neurosurgery Working Group of the Royal College of Psychiatrists. London: Royal College of Psychiatrists.
Rück, C., Andreewitch, S., Flyckt, K. et al (2003) Capsulotomy for refractory anxiety disorders: long-term follow-up of 26 patients. American Journal of Psychiatry, 160, 513521.
Rush, A. J., George, M. S., Sackeim, H. A. et al (2000) Vagus nerve stimulation (VNS) for treatment-resistant depressions: a multicenter study. Biological Psychiatry, 47, 276286.
Sackeim, H. A., Rush, A. J., George, M. S. et al (2001) Vagus nerve stimulation (VNS) for treatment-resistant depression: efficacy, side effects and predictors of outcome. Neuropsychopharmacology, 25, 713728.
Saxena, S., Brody, A. L., Schwartz, J. M. et al (1998) Neuroimaging and frontal–subcortical circuitry in obsessive-compulsive disorder. British Journal of Psychiatry, 173 (suppl. 35), 2637.
Schneider, F., Habel, U., Volkmann, J. et al (2003) Deep brain stimulation of the subthalamic nucleus enhances emotional processing in Parkinson disease. Archives of General Psychiatry, 60, 296302.
Skoog, G. & Skoog, I. (1999) A 40-year follow-up of patients with obsessive-compulsive disorder. Archives of General Psychiatry, 56, 121127.
Spangler, W. J., Cosgrove, G. R., Ballantine, H. T. Jr. et al (1996) Magnetic resonance image-guided stereotactic cingulotomy for intractable psychiatric disease. Neurosurgery, 38, 10711076; discussion 1076–1078.
Ström-Olsen, R. & Carlisle, S. (1971) Bi-frontal stereotactic tractotomy. A follow-up study of its effects on 210 patients. British Journal of Psychiatry, 118, 141154.
Tan, E., Marks, I. M. & Marset, P. (1971) Bimedial leucotomy in obsessive-compulsive neurosis: a controlled serial enquiry. British Journal of Psychiatry, 118, 155164.
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BJPsych Advances
  • ISSN: 1355-5146
  • EISSN: 1472-1481
  • URL: /core/journals/bjpsych-advances
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Neurosurgery for mental disorder

  • David Christmas, Colin Morrison, Muftah S. Eljamel and Keith Matthews
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