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Genetic Expectations of Polar Body Twinning

  • D.E. Goldgar (a1) (a2) and W.J. Kimberling (a1) (a3)
Abstract

The expected correlation between polar body twins depends upon the frequency and distribution of chiasmata occurring during oogenesis. We have estimated the expected values of these correlations using assumptions believed to be biologically valid. The expected value of the overall correlation between first polar body twins is estimated to be 0.38 and that between second polar body twins is estimated to be 0.51. There is little difference between the correlation of DZ twins and that expected for second polar body twins.

The correlation for a specific locus depends upon its distance from the centromere for both types of polar body twins. This effect is especially marked for second polar body twins. For second polar body twins, loci at or near the telomere will have a correlation close to that expected for first polar body twins. It is concluded that only those marker genes that lie at or close to the centromere are appropriate for the detection of polar body twinning.

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Corresponding author
Boys Town Institute, 555 North 30th Street, Omaha, NE 68131, USA
References
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1. Cook, PJL, Noades, J, Hopkinson, DA, Robson, EB (1972): Demonstration of a sex difference in recombination fraction in the loose linkage, Rh and PGM1 . Ann Hum Genet 35:239242.
2. Elston, RC, Boklage, CE (1978): An examination of fundamental assumptions of the twin method. In “Progress in Clinical and Biological Research: Twin Studies,” Nance, WE, Allen, G, and Parisi, P (eds): New York: Alan R. Liss, Part A, pp 189200.
3. Fenger, K, Sorenson, SA (1975): Evaluation of a possible sex difference in recombination for the ABO-AK linkage. Am J Hum Genet 27:784788.
4. Hulten, M (1974): Chiasma distribution at diakinesis in the normal human male. Hereditas 76:5578.
5. Morton, NE, Rao, DC, Lindstein, J, Hulten, M, Yee, S (1977): A chiasma map of man. Hum Hered 27:3851.
6. Renwick, JH (1971): The mapping of human chromosomes. Ann Rev Genet 5:81120.
7. Suarez, B, Reich, T, Fishman, PM (1979): Variability in sib pair genetic identity. Hum Hered 29:3741.
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Acta geneticae medicae et gemellologiae: twin research
  • ISSN: 0001-5660
  • EISSN: 2059-6324
  • URL: /core/journals/amg-acta-geneticae-medicae-et-gemellologiae-twin-research
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