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Avian influenza virus: prospects for prevention and control by vaccination

Published online by Cambridge University Press:  28 February 2007

Chang-Won Lee  and
David L. Suarez
Chang-Won Lee
Affiliation:
Southeast Poultry Research Laboratory, Agricultural Research Service, U.S. Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
David L. Suarez*
Affiliation:
Southeast Poultry Research Laboratory, Agricultural Research Service, U.S. Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
*
*E-mail: dsuarez@seprl.usda.gov
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Abstract

Although vaccination does not always prevent infection of avian influenza (AI) virus, the clear benefit of vaccination is in its ability to prevent disease and to reduce the amount of virus in circulation. Thus, judicious use of vaccination can be an important component of an AI control program. However, the long-term use of vaccination without eradication may result in the selection of the antigenically divergent strains, which compromises the value of vaccination. In this review, the effectiveness of currently available and future AI vaccines is discussed with suggestions for the ideal use of vaccination even with antigenic drift of the virus.

Keywords

avian influenzavaccinationantigenic drift
Type
Research Article
Information
Animal Health Research Reviews , Volume 6 , Issue 1 , June 2005 , pp. 1 - 15
Copyright
Copyright © CAB International 2005

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