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Halothane sensitivity as a field test for stress-susceptibility in the pig

Published online by Cambridge University Press:  02 September 2010

A. J. Webb
Affiliation:
ARC Animal Breeding Research Organisation, West Mains Road, Edinburgh EH9 3JQ
C. H. C. Jordan
Affiliation:
ARC Animal Breeding Research Organisation, West Mains Road, Edinburgh EH9 3JQ
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Abstract

The possible use of a pig's reaction to the anaesthetic halothane as a field test for Porcine Stress Syndrome in genetic improvement pro-grammes was investigated. A standard 3-min halothane test gave incidences of positive reaction of 20% in a composite Pietrain/Hampshire line, 5% in Norwegian Landrace, 1% in Hampshires and zero in Durocs, Large Whites and N. American Yorkshires. In the Pietrain/Hampshire population, two generations oftwo-way selection on the test gave a divergence in incidence of positive reaction of 85%, and the frequencies of affected progeny supported the hypothesis of monogenic recessive inheritance. From second tests made 20 days after the first, the probability of misclassifying a pig's reaction on one test was 5 ± 1%. Positive reactors had significantly shorter and leaner carcasses, fewer pigs born alive, poorer meat quality, higher mortality and greater plasma creatine phosphokinase activity than negative reactors.

Type
Research Article
Copyright
Copyright © British Society of Animal Science 1978

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References

REFERENCES

Agergaard, N., Hyldgaard-Jensen, J., Jorgensen, P. F., Nielsen, P. B. and Moust-gaard, J. 1976. Biochemical-genetic constitution of Danish Landrace pigs: an immuno-genetic and biochemical study. Acta Agric. scand. 26: 255263.CrossRefGoogle Scholar
Allen, W. M., Collis, K. A., Berret, S. and Bell, J. C. 1976. Factors which may affect CK estimations in the pig. Proc. 3rd int. Conf. Production Disease in Farm Animals, Wageningen pp. 179182. Pudoc, Wageningen.Google Scholar
Allen, W. M. and Patterson, D. S. P. 1971. The possible relationship between plasma creatine phosphokinase activity and muscle characteristics in the pig. Proc. 2nd int. Symp. Condition Meat Quality of Pigs, Zeist, pp. 9096. Pudoc, Wageningen.Google Scholar
Ball, R. A., Topel, D. G., Annis, C. L. and Christian, L. L. 1973. Diagnostic aspects of Porcine Stress Syndrome. Proc. 76th Ann. Mtg US Animal Health Ass., Miami Beach, pp. 517530.Google Scholar
Cheah, K. S. and Cheah, A. M. 1976. The trigger for PSE condition in stress-susceptible pigs. J.Sci. FdAgric. 27: 11371144.CrossRefGoogle ScholarPubMed
Christian, L. 1976. Genetic improvement in the production of quality pork. Ann. Rep. Iowa NC–103, 1975–76. Iowa State Univ. (Mimeograph.)Google Scholar
Clark, J. B. K. 1973. The effect of pre-slaughter influences on quality. Proc. Inst. Fd Sci. Technol. 6: 136144.Google Scholar
Cook, G. L., Smith, D. H. and Steane, D. E. 1971. The progress and penetration of the accreditation scheme in Britain 1966–1970. Proc. 10th int. Congr. Anim. Prod., Paris.Google Scholar
Cuthbertson, A. 1968. PIDA dissection techniques. Proc. Symp. Methods of Carcass Evaluation, Dublin. Eur. Ass. Anim. Prod.Google Scholar
Eikelenboom, G. and Minkema, D. 1974. Prediction of pale, soft, exudative muscle with a non-lethal test for halothane-induced porcine malignant hyperthermia syndrome. Tijdschr. Diergeneesk. 99: 421426.Google Scholar
Eikelenboom, G., Minkema, D. and Van eldik, P. 1976. The application of the halothane test: differences in production characteristics between pigs qualified as reactors (MHS-susceptible) and non-reactors. Proc. 3rd int. Conf. Production Disease in Farm Animals, Wageningen, pp. 183187. Pudoc, Wageningen.Google Scholar
Jensen, E. L., Smith, C., Baker, L. N. and Cox, D. F. 1968. Quantitative studies on blood group and serum protein systems in pigs. II. Effects on production and reproduction. J. Anim. Sci. 27: 856862.Google Scholar
Jorgensen, P. F., Hyldgaard-Jensen, J., Eikelenboom, G. and Moustgaard, J. 1976. Meat quality, halothane sensitivity and blood parameters. Proc. 3rd int. Conf. Production Disease in Farm Animals, Wageningen, pp. 200202. Pudoc, Wageningen.Google Scholar
Lundstrom, K. 1975. Genetic parameters estimated on data from the Swedish pig progeny testing with special emphasis on meat colour. Swed. J. agric. Res. 5: 209221.Google Scholar
Minkema, D., Eikelenboom, G. and Van eldik, P. 1976. Inheritance of M.H.S.-susceptibility in pigs. Proc. 3rd int. Conf. Production Disease in Farm Animals, Wage-ningen, pp. 203207. Pudoc, Wageningen.Google Scholar
Monin, G., Ollivier, L. and Sellier, P. 1976. Study of the malignant hyperthermia syndrome in Pietrain breed: first results. Annls Zootech. 25: 447448 (Abstr.).Google Scholar
Morris, C. A. 1975. Genetic relationships of reproduction with growth and with carcass traits in British pigs. Anim. Prod. 20: 3144.Google Scholar
Ollivier, L., Sellier, P. and Monin, G. 1975. [Genetic determination of the malignant hyperthermia syndrome in the Pietrain pig.] Annls Genet. Sel. anim. 7: 159166.Google Scholar
Ollivier, L., Sellier, P. and Monin, G. 1976. Frequency of the malignant hyperthermia syndrome (MHS) in some French pig populations: preliminary results. Proc. 3rd int. Conf. Production Disease in Farm Animals, Wageningen, pp. 208210. Pudoc, Wageningen.Google Scholar
Rasmusen, B. A. and Christian, L. L. 1976. H blood types in pigs as predictors of stress susceptibility. Science, N. Y. 191: 947948.CrossRefGoogle ScholarPubMed
Smith, C. and Bampton, P. 1977. Inheritance of reaction to halothane anaesthesia in pigs. Genet. Res. 29: 287292.CrossRefGoogle ScholarPubMed
Sybesma, W. and Eikelenboom, G. 1969. Malignant hyperthermia syndrome in pigs. Neth. J. Vet. Sci. 2: 155160.Google Scholar
Verstegen, M. W. A., Brascamp, E. W., Hel, W. van der, Groot, P. N. de and Eikelen-boom, G. 1976. Effect of susceptibility to malignant hyperthermia syndrome (MHS) as detected by halothane on some production and energy balance characteristics in Dutch Landrace pigs. Proc. 3rd int. Conf. Production Disease in Farm Animals, Wageningen, pp. 188192. Pudoc, Wageningen.Google Scholar
Webb, A. J. and Smith, C. 1976. Some preliminary observations on the inheritance and application of halothane-induced MHS in pigs. Proc. 3rd int. Conf. Production Disease in Farm Animals, Wageningen, pp. 211213. Pudoc, Wageningen.Google Scholar