Hostname: page-component-76fb5796d-9pm4c Total loading time: 0 Render date: 2024-04-28T15:09:49.825Z Has data issue: false hasContentIssue false

Milk production and reproductive performance of cows induced into lactation and treated with bovine somatotropin

Published online by Cambridge University Press:  09 March 2007

M. Mellado*
Affiliation:
Department of Nutrition, University Autonoma Agraria Antonio Narro, Saltillo, México
E. Nazarre
Affiliation:
Department of Nutrition, University Autonoma Agraria Antonio Narro, Saltillo, México
L. Olivares
Affiliation:
Department of Nutrition, University Autonoma Agraria Antonio Narro, Saltillo, México
F. Pastor
Affiliation:
Department of Nutrition, University Autonoma Agraria Antonio Narro, Saltillo, México
A. Estrada
Affiliation:
Faculty of Veterinary Medicine and Animal Science, University Autonoma of Sinaloa, Culiacan, Mexico
*
Get access

Abstract

Milk production and reproductive performance of pluriparous dairy cows was compared for cows whose lactations were induced by hormonal treatment or followed natural calving. The study was conducted on 179 high-yielding dairy cows in a large dairy operation in a hot arid environment of northern Mexico, where bovine somatotropin (bST) was routinely used in all cows. To induce lactation, 98 cows that had previously failed to become pregnant were treated with 500 mg bST on days 1, 8 and 21. From days 2 to 8, cows were treated with oestradiol cypionate (0·30 mg/kg live weight (LW) per day) and progesterone (0·28 mg/kg LW per day). From days 9 to 15, oestradiol cypionate alone was given. PGF was given on day 16. Nothing was administered on days 17 and 18, and 15 mg flumetasone was administered from days 19 to 21. Lactation was induced successfully in all 98 cows subjected to the hormone treatment. All cows received 500 mg bST every 14 days throughout lactation from 63±7 days after lactation had started. Cows with induced lactations produced less (P<0·01) milk per 305-day lactation (9599±1387 kg) than controls (12 302±1245 kg). Proportion of cows pregnant was similar in induced cows and non-treated cows (71 v. 75%). Induction of lactation was associated with increased numbers of services per pregnancy (5·8±4·0 v. 4·22±2·98; P<0·01) compared with controls; however, impaired reproduction might not necessarily have been related to the hormonal treatment to induce lactation, but due to the nature of the cows utilized for this treatment group. This protocol can be used on dairy farms where bST treatment and prolonged steroid administration of dairy cows is legally permitted.

Type
Research Article
Copyright
Copyright © British Society of Animal Science 2006

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baldi, A., Modina, S., Cheli, F., Gandolfi, F., Pinotti, L., Baraldi Scesi, L., Fantuz, F. and Dell'Orto, V. 2002. Bovine somatotropin administration to dairy goats in late lactation: Effects on mammary gland function, composition and morphology. Journal of Dairy Science 85: 10931102.CrossRefGoogle ScholarPubMed
Bar-Peled, U., Maltz, E., Bruckental, I., Folman, Y., Kali, Y., Gacitua, H., Lehrer, A. R., Knight, C. H., Robinzon, B., Voet, H. and Tagari, H. 1995. Relationship between frequent milking or suckling in early lactation and milk production of high producing dairy cows. Journal of Dairy Science 78: 27262736.Google Scholar
Capuco, A. V., Ellis, S. E., Hale, S. A., Long, E., Erdman, R. A., Zhao, X. and Paape, M. J. 2003. Lactation persistency: insights from mammary cell proliferation studies. Journal of Animal Science 81: 1831.Google Scholar
Capuco, A. V., Keys, J. E. and Smith, J. J. 1989. Somatotrophin increases thyroxine-5'-monodeiodinasa activity in lactating mammary tissue of the cows. Journal of Endocrinology 121: 205211.CrossRefGoogle Scholar
Chakriyarat, S., Head, H. H., Thatcher, W. W., Neal, F. C. and Wilcox, C. J. 1978. Induction of lactation: lactational, physiological, and hormone response in the bovine. Journal of Dairy Science 61: 17151724.Google Scholar
Collier, R. J., Bauman, D. E. and Hays, R. L. 1977. Effect of reserpine on milk production and serum prolactin of cows hormonally induced into lactation. Journal of Dairy Science 60: 896901.Google Scholar
Collier, R. J., Bauman, D. E. and Hays, R. L. 1975. Milk production and reproductive performance of cows hormonally induced into lactation. Journal of Dairy Science 58: 15241527.CrossRefGoogle Scholar
Collier, R. J., Byatt, J. C., Denham, S. C., Eppard, P. J., Fabellar, A. C., Hintz, R. L., McGrath, M. F., McLaughlin, C. L., Shearer, J. K., Veenhuizen, J. and Vicini, J. L. 2001. Effects of sustained release bovine somatotropine (sometribove) on animal health in commercial dairy herds. Journal of Dairy Science 84: 10981108.Google Scholar
Davis, S. R., Welch, R. A. S., Pearce, M. G. and Peterson, A. J. 1982. Induction of lactation in nonpregnant cows by estradiol-17-β and progesterone from an intravaginal sponge. Journal of Dairy Science 66: 450457.Google Scholar
DeRensis, F. and Scaramuzzi, R. J. 2003. Heat stress and seasonal effects on reproduction in the dairy cow–a review. Theriogenology 60: 11391151.CrossRefGoogle Scholar
Dohoo, I. R., DesCoteaux, L., Leslie, K., Fredeen, A., Shewfelt, W., Preston, A. and Dowling, P. 2003. A meta-analysis review of the effects of recombinant bovine somatotropin. 2. Effects on animal health, reproductive performance, and culling. Canadian Journal of Veterinary Research 67: 252264.Google ScholarPubMed
Erb, R. E., Monk, E. L., Mollett, T. A., Malven, P. V. and Callahan, C. J. 1976. Estrogen, progesterone, prolactin, and other changes associated, with bovine lactation induced with estradiol-17β and progesterone. Journal of Animal Science 42: 644654.CrossRefGoogle Scholar
Forsyth, I. A. 1996. The insulin-like growth factor and epidermal growth factor families in mammary cell growth in ruminants: action and interaction with hormones. Journal of Dairy Science 79: 10851096.Google Scholar
Fulkerson, W. J. 1978. Artificial induction of lactation: A comparative study in heifers. Australian Journal of Biological Science 3: 6571.Google Scholar
Harness, J. R., Anderson, R. R., Thompson, L. J., Early, D. M. and Younis, A. K. 1978. Induction of lactation by two techniques: Success rate, milk composition, estrogen and progesterone in serum and milk, and ovarian effects. Journal of Dairy Science 61: 17251735.Google Scholar
Henderson, A. J., Blatchford, D. R. and Peaker, M. 1985. The effects of long-term thrice-daily milking on milk secretion in the goat: Evidence for mammary growth. Quarterly Journal of Experimental Physiology 70: 557565.Google Scholar
Jordan, D. L., Erb, R. E., Malven, P. V., Callahan, C. J. and Veenhuizen, E. L. 1981. Artificial induction of lactation in cattle: Effect of modified treatments on milk yield, fertility and hormones in blood plasma and milk. Theriogenology 16: 315329.CrossRefGoogle ScholarPubMed
Judge, L. J., Bartlett, P. C., Lloyd, J. W. and Erskine, R. J. 1999. Recombinant bovine somatotropin: association with reproductive performance in dairy cattle. Theriogenology 52: 481496.Google Scholar
Kensinger, R. S., Bauman, D. E. and Collier, R. J. 1979. Season and treatment effects on serum prolactin and milk yield during induced lactation. Journal of Dairy Science 62: 18801888.Google Scholar
Kirby, C. J., Wilson, S. J. and Lucy, M. C. 1997. Response of dairy cows treated with bovine somatotropin to a luteoliyic dose of prostaglandin F . Journal of Dairy Science 80: 286294.CrossRefGoogle Scholar
Knight, C. H., Fowler, P. A. and Wilde, C. J. 1990. Galactopoietic and mammogenic effects of long-term treatment with bovine growth hormone and thrice daily milking in goats. Journal of Endocrinology 127: 129138.Google Scholar
Knight, C. H. and Sorensen, A. 2000 Manipulation of lactation persistency with maintenance of milk quality. Journal of DairyScience 83: (suppl. 1)24.Google Scholar
Lefebvre, D. M. and Block, E. 1992. Effect of recombinant bovine somatotropin on estradiol-induced estrous behaviour in ovariectomized heifers. Journal of Dairy Science 75: 14611464.Google Scholar
Lembowicz, K., Rabek, A. and Skrzeczkowski, L. 1982. Hormonal induction of lactation in the cow. British Veterinary Journal 138: 203208.Google Scholar
Luna-Dominguez, J. E., Enns, R. M., Armstrong, D. V. and Ax, R. L. 2000. Reproductive performance of Holstein cows receiving somatotropin. Journal of Dairy Science 83: 14511455.Google Scholar
Magliaro, A. L., Kensinger, R. S., Ford, S. A., O'Connor, M. L., Muller, L. D. and Graboski, R. 2004. Induced lactation in nonpregnant cows and response to bovine somatotropin. Journal of Dairy Science 87: 32903297.CrossRefGoogle ScholarPubMed
Mellado, M. and Meza-Herrera, C. A. 2002. Influence of season and environment on fertility of goats in a hot-arid environment. Journal of Agricultural Science 138: 97102.CrossRefGoogle Scholar
Moreira, F., Badinga, L., Burnley, C. and Thatcher, W. W. 2002. Bovine somatotropin increases embryonic development in superovulated cows and improves post-transfer pregnancy rates when given to lactating recipient cows. Theriogenology 57: 13711387.CrossRefGoogle ScholarPubMed
Moreira, F., Orlandi, C. A., Risco, C. A., Mattos, R., Lopez, F. and Thatcher, W. W. 2001. Effects of presynchronization and bovine somatotropin on pregnancy rates to a timed artificial insemination protocol in lactating dairy cows. Journal of Dairy Science 84: 16461659.CrossRefGoogle ScholarPubMed
Peel, C. J., Taylor, J. W., Robinson, I. B., McGowan, A. A., Holley, R. D. and Findlay, J. K. 1978. The importance of prolactin and the milking stimulus in the artificial induction of lactation in cows. Australian Journal of Biological Science 31: 187195.Google Scholar
Pryce, J. E., Royal, M. D., Garnsworthy, P. C. and Mao, I. L. 2004. Fertility in the high-producing dairy cow. Livestock Production Science 86: 125135.Google Scholar
Radcliff, R. P., VandeHaar, M. J., Skidmore, A. L., Chapin, L. T., Radke, B. R., Lloyd, J. W., Stanisiewski, E. P. and Tucker, H. A. 2003. Effect of diet and bovine somatotropin on heifer growth and mammary development. Journal of Dairy Science 80: 19962003.Google Scholar
Santos, J. E. P., Juchem, S. O., Cerri, R. L. A., Galvao, K. N., Chebel, R. C., Thatcher, W. W., Dei, C. S. and Bilby, C. R. 2004. Effect of bST and reproductive management on reproductive performance of Holstein Dairy cows. Journal of Dairy Science 87: 868881.Google Scholar
Sakamoto, K., Komatsu, T., Kobayashi, T., Rose, M. T., Aso, H., Hagino, A. and Obara, Y. 2005. Growth hormone acts on the synthesis and secretion of alpha-casein in bovine mammary epithelial cells. Journal of Dairy Research 72: 264270.CrossRefGoogle ScholarPubMed
Sawyer, G. J., Fulkerson, W. J., Martin, G. B. and Christine, G. 1986. Artificial induction of lactation in cattle: initiation of lactation and estrogen and progesterone concentrations in milk. Journal of Dairy Science 69: 15361544.Google Scholar
Sejrsen, K., Foldager, J., Sorensen, M. T., Akers, R. M. and Bauman, D. E. 1986. Effect of exogenous bovine somatotropin on pubertal mammary development in heifers. Journal of Dairy Science 69: 15281535.CrossRefGoogle ScholarPubMed
Sejrsen, K., Purup, S., Vestergaard, M., Weber, M. S. and Knight, C. H. 1999. Growth hormone and mammary development. Domestic Animal Endocrinology 17: 117129.Google Scholar
Smith, K. L. and Schanbacher, F. L. 1973. Hormone induce lactation in the bovine. I. Lactational performance following injections of 17β-estradiol and progesterone. Journal of Dairy Science 56: 738743.CrossRefGoogle Scholar
Statistical Analysis Systems Institute. 1996. SAS system (release 6·12). SAS Institute Inc., Cary, NC.Google Scholar
Tervit, H. R., Fairclough, R. J., McGowan, L. T., MacKensie, D. D. S., MacMillan, K. L. and Peterson, A. J. 1980. Induction of lactation in dry dairy cattle. New Zealand Veterinary Journal 28: 1519.CrossRefGoogle Scholar