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Tolerance of bivalve mollusc hemocytes to variable oxygenavailability: a mitochondrial origin?

Published online by Cambridge University Press:  04 July 2013

Ludovic Donaghy ,
Sébastien Artigaud ,
Rossana Sussarellu ,
Christophe Lambert ,
Nelly Le Goïc ,
Hélène Hégaret  and
Philippe Soudant
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Abstract

Bivalve molluscs survive lack of oxygen and may present cellular characteristics allowingtolerance to oxygen deprivation. The objective of the present work was to determine invitro responses of circulating cells (i.e., hemocytes) of Pacific oyster,Crassostrea gigas, to oxygen deprivation by analysis of mitochondrialmembrane potential (ΔΨm) and reactive oxygen species (ROS) production.Hemocytes submitted to oxygen deprivation showed a reduced ROS production and an increasedΔΨm. Confrontation of present results with recently reported findingsallows us to hypothesize the existence of an alternative mitochondrial reductase, and theinvolvement of mitochondrial potassium channel in maintenance of ΔΨm.Tolerance of bivalve hemocytes to variable oxygen availability appears, at leastpartially, related to mitochondrial specificities.

Keywords

HemocyteHypoxiaMitochondriaReactive oxygen speciesFlow cytometryOyster

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Type
Perspectives
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Aquatic Living Resources , Volume 26 , Issue 3 , 2013 , pp. 257 - 261
Copyright
© EDP Sciences, IFREMER, IRD 2013

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