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Vitamin K and osteoporosis

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Binkley N. et al. Vitamin K treatment reduces undercarboxylated osteocalcin but does not alter bone turnover, density, or geometry in healthy postmenopausal North American women. J Bone Miner Res. 2009 Jun;24(6):983–91.
Iwamoto J. et al. High-dose vitamin K supplementation reduces fracture incidence in postmenopausal women: a review of the literature. Nutr Res. 2009 Apr;29(4):221–8.
Cockayne S. et al. Vitamin K and the prevention of fractures: systematic review and meta-analysis of randomized controlled trials. Arch Intern Med. 2006 Jun 26;166(12):1256–61.

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Published online by Cambridge University Press:  11 September 2013

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In a nutshell

Vitamin K is required for bone health, probably in doses greater than conventional RDI levels.

There is reasonable but not conclusive evidence that vit.K supplements can help prevent osteopenic fractures, even if it does notnecessarily increase BMD. Vitamin K should therefore be part of the nutritional cocktail for osteporosis prevention.

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Brief Report
Information
Arbor Clinical Nutrition Updates , Volume 309 , July 2009 , pp. 1 - 3
Copyright
Copyright © Cambridge University Press 2009

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