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Systematic reviews in emergency medicine: Part II. Critical appraisal of review quality, data synthesis and result interpretation

  • Peter J. Zed (a1) (a2) (a3), Brian H. Rowe (a4), Peter S. Loewen (a1) (a2) and Riyad B. Abu-Laban (a3) (a5)
Abstract
ABSTRACT

Reviews of the medical literature have always been an important resource for physicians. Increasingly, qualitative and quantitative systematic reviews (SRs) have replaced the traditional “narrative review” as a means of capturing and summarizing current evidence on a topic or, when possible, answering a specific clinical question. This paper is Part II of a 2-part series designed to provide emergency physicians with the background necessary to locate, critically evaluate and interpret SRs. The paper expands on the critical appraisal principles discussed in Part I by focusing on quality assessment, data synthesis and interpretation of results. To illustrate key points and facilitate readability, examples from the emergency medicine literature have been included and technical details have been kept to a minimum. The references, however, are comprehensive and provide a resource for readers seeking further information.

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Copyright
Corresponding author
CSU Pharmaceutical Sciences, Vancouver General Hospital, 855 West 12th Ave., Vancouver BC V5Z 1M9; 604 875-4077, fax 604 875-5267, zed@interchange.ubc.ca
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

2. KD Kelly , A Travers , M Dorgan , L Slater , BH. Rowe Evaluating the quality of systematic reviews in the emergency medicine literature. Ann Emerg Med 2001;38:51826.

3. MO Meade , S. Richardson Selecting and appraising studies for systematic review. Ann Intern Med 1997;127:5317.

4. D Moher , B Pham , A Jones , DJ Cook , AR Jadad , M Moher , et al. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? Lancet 1998;352:60913.

5. D Moher , DJ Cook , S Eastwood , I Olkin , D Rennie , DF. Stroup Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement. Quality of Reporting of Meta-analyses. Lancet 1999;354:1896900.

6. AR Jadad , RA Moore , D Carroll , C Jenkinson , DJ Reynolds , DJ Gavaghan , et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996;17:112.

7. HD Clark , GA Wells , C Huet , FA McAlister , LR Salmi , D Fergusson , et al. Assessing the quality of randomized trials: reliability of the Jadad scale. Control Clin Trials 1999;20:44852.

8. BH Rowe , JA Bretzlaff , C Bourdon , GW Bota , CA Camargo Jr. Intravenous magnesium sulfate treatment for acute asthma in the emergency department: a systematic review of the literature. Ann Emerg Med 2000;36:18190.

14. AD Oxman , GH. Guyatt A consumer’s guide to subgroup analyses. Ann Intern Med 1992;116:7884.

15. D Moher , KF Schultz , DG. Altman The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials. Lancet 2001;357:11914.

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Canadian Journal of Emergency Medicine
  • ISSN: -
  • EISSN: 1481-8035
  • URL: /core/journals/canadian-journal-of-emergency-medicine
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