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Cleft mitral valve in transposition with intact ventricular septum

  • Samuel Menahem (a1) and Robert H. Anderson (a2)

We describe two cases of an isolated cleft of the mitral valve in transposition with intact ventricular septum. The cleft is positioned leftward in the pulmonary leaflet, at about 2 o’clock, when viewed from below looking at the cardiac short axis with the right ventricle to one’s left hand. Such clefts, when seen in the Taussig-Bing malformation are also positioned leftward.

In keeping with our current knowledge of cardiac development, our cases provide further evidence that transposition with an intact ventricular septum is the end-point of the Taussig-Bing spectrum.

Corresponding author
Correspondence to: Samuel Menahem, Murdoch Children’s Research Institute, Monash University Heart and Chest Research Institute, Royal Children’s Hospital, Flemington Road, Parkville, Vic 3052, Australia. Tel: +61 3 9345 5712; Fax: +61 3 9345 6001; E-mail:
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SmallhornJF, TommasiniG, AndersonRH, MacartneyFJ. Assessment of atrioventricular septal defects by 2 dimensional echocardiography.Br Heart J1982; 47: 100121.

SigfussonG, EttedgniJA, SilvermanNH, AndersonRH. Is a cleft in the anterior leaflet of an otherwise normal mitral valve an atrioventricular canal malformation?J Am Coll Cardiol1995; 26: 508515.

Di SegniE, BassJL, LucasRV, EinzigS. Isolated cleft mitralvalve: a variety of congenital mitral regurgitation identified by two dimensional echocardiography.Am J Cardiol1983; 51: 927931.

SmallhornJF, de LevalM, StarkJ, SommervilleJ, TaylorJF, AndersonRH, MacartneyFJ. Isolated mitral cleft: two dimensional echocardiographic assessment and differentiation from “clefts” associated with atrioventricular septal defects.Br Heart J1982; 48: 108116.

TamuraM, MenahemS, BrizardC. Clinical features and management of isolated cleft mitral valve in childhood.J Am Coll Cardiol2000; 35: 764770.

SotoB, CeballosR, NathPH, BineRM, PacificoAD, BegeronLM. Overriding AV valves, an angiographic–anatomic correlate.Int J Cardiol1985; 9: 327339.

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Cardiology in the Young
  • ISSN: 1047-9511
  • EISSN: 1467-1107
  • URL: /core/journals/cardiology-in-the-young
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