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Holt–Oram syndrome with aortopulmonary window – a rare association

  • Sunil K. Srinivas (a1), Vijayalakshmi I. Balekundri (a2) and Cholenahally N. Manjunath (a3)

A 4-month-old male infant presented with recurrent cough for 2 months. He had a shortened right upper limb with absent right thumb and continuous murmur in the left parasternal area. The X-ray showed an absent radius and the first metacarpal and phalyngeal bones on the right side. Echocardiogram revealed aortopulmonary window and small secundum atrial septal defect. Aortopulmonary window was successfully treated by device closure. Holt–Oram syndrome with aortopulmonary window is an extremely rare association.

Corresponding author
Correspondence to: Dr S. K. Srinivas, MD, Fellow, Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, Karnataka 560069, India. Tel: +91-80-26650031; Fax: +91-80-22977422; E-mail:
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Cardiology in the Young
  • ISSN: 1047-9511
  • EISSN: 1467-1107
  • URL: /core/journals/cardiology-in-the-young
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