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Premature ventricular contractions as a side effect of filgrastim in a child with B-thalassaemia

Part of: Electrophysiology

Published online by Cambridge University Press:  29 August 2017

Hanan F. Nazir Open the ORCID record for Hanan F. Nazir [Opens in a new window] ,
Niranjan Joshi  and
Yasser A. Wali
Hanan F. Nazir*
Affiliation:
Child Health Department, SQUH, Muscat, Oman Department of Pediatrics, Faculty of Medicine, Alexandria University, Alexandria, Egypt
Niranjan Joshi
Affiliation:
Child Health Department, SQUH, Muscat, Oman
Yasser A. Wali
Affiliation:
Child Health Department, SQUH, Muscat, Oman Department of Pediatrics, Faculty of Medicine, Alexandria University, Alexandria, Egypt
*
Correspondence to: H. F. Nazir, Child Health Department, SQUH, Alkhoudh, Muscat 123, PO Box 38, Oman. Tel: +968 24 147777; Fax: +968 24147777; E-mail: dr.hanannazir@yahoo.com
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Abstract

Premature ventricular contractions are a rare side effect of filgrastim, reported mainly in elderly men. Here we report the case of a 9-year-old child with thalassaemia who developed frequent premature ventricular contractions after three doses of filgrastim were given for deferiprone-induced agranulocytosis. The arrhythmia resolved 3 weeks after discontinuation of filgrastim. Children treated with filgrastim should be carefully monitored for potentially serious arrhythmia.

Keywords

Premature ventricular contractionsfilgrastimB-thalassaemiachildagranulocytosis
Type
Brief Report
Information
Cardiology in the Young , Volume 28 , Issue 1 , January 2018 , pp. 155 - 158
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Copyright
© Cambridge University Press 2017 

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