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Risk for prolonged QT interval and associated outcomes in children with early restrictive eating patterns

  • Karine Guerrier (a1), Laurie Mitan (a2), Yu Wang (a3) and Richard J. Czosek (a1)

Abstract

Aim

This study aimed to describe the frequency of QTc prolongation in children with restrictive eating disorders early in the course of disease admitted for inpatient therapy, to determine the frequency of associated ventricular arrhythmia, and to evaluate the relationship between QTc interval and concomitant electrolyte abnormalities and rate of weight loss.

Methods

This was a retrospective cohort study of patients aged 11–25 years with early restrictive eating disorders.

Results

In all, 82 patients met the inclusion criteria (84% female). In total, 9.8% had prolonged QTc interval during hospitalisation. Patients with prolonged QTc had significantly higher resting heart rates (p=0.006), but there was no association with hypokalaemia (p=0.31), hypomagnesaemia (p=0.43), hypophosphataemia (p=1), or rate of weight loss (p=1).

Conclusion

Mild QTc prolongation in patients with restrictive eating disorders is not related to electrolyte abnormalities or rate of weight loss in this population, suggesting that investigation about other potential risk factors of prolonged QTc interval may be warranted.

Copyright

Corresponding author

Correspondence to: K. Guerrier, DO, MPH, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, MLC 2003, Cincinnati, OH 45229, United States of America. Tel: +513-636-4432; Fax: +513-636-3952; E-mail: Karine.Guerrier@cchmc.org

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Cardiology in the Young
  • ISSN: 1047-9511
  • EISSN: 1467-1107
  • URL: /core/journals/cardiology-in-the-young
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