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Successful use of oral prostaglandin E1 derivative for maintaining ductus-dependent systemic circulation in a neonate with trisomy 18

Part of: Basic Science

Published online by Cambridge University Press:  22 August 2019

Akiko Miyake ,
Seigo Okada Open the ORCID record for Seigo Okada [Opens in a new window]  and
Yuichi Ishikawa
Akiko Miyake
Affiliation:
Department of Pediatrics, Saiseikai Shimonoseki General Hospital, Shimonoseki, Yamaguchi, Japan
Seigo Okada*
Affiliation:
Department of Pediatrics, Saiseikai Shimonoseki General Hospital, Shimonoseki, Yamaguchi, Japan
Yuichi Ishikawa
Affiliation:
Department of Pediatrics, Saiseikai Shimonoseki General Hospital, Shimonoseki, Yamaguchi, Japan
*
Author for correspondence: S. Okada, MD, PhD, Department of Pediatrics, Saiseikai Shimonoseki General Hospital, 8-5-1, Yasuoka, Shimonoseki, Yamaguchi 759-6603, Japan. Tel: 81-83-262-2300; Fax: 81-83-262-2301; E-mail: sokada0901@gmail.com
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Abstract

A Japanese female infant with trisomy 18 was diagnosed with hypoplastic left heart syndrome variant. She was administered oral prostaglandin E1 every 6 hours through a feeding tube as an alternative drug for lipo-prostaglandin E1. Oral prostaglandin E1 was effective for maintenance of the ductus arteriosus and may serve as a palliative treatment approach.

Keywords

Chromosomal disorderCHDpalliative treatmentpatent ductus arteriosus
Type
Brief Report
Information
Cardiology in the Young , Volume 29 , Issue 9 , September 2019 , pp. 1222 - 1224
Copyright
© Cambridge University Press 2019 

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