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Systemic hypertension in an infant with unrepaired tetralogy of Fallot: case report

  • Michael Khoury (a1), Michael Kallile (a2), Joseph May (a2) and Rajesh Punn (a2)
  • DOI:
  • Published online: 13 November 2012

Patients with severe right ventricular outflow tract obstruction in tetralogy of Fallot typically have right-to-left shunting, resulting in low pulmonary blood flow and cyanosis. Here we present the case of an infant with tetralogy of Fallot and severe pulmonary valve stenosis, complicated by systemic hypertension, the presence of which altered flow dynamics and possibly prevented cyanosis.

Corresponding author
Correspondence to: Dr R. Punn, MD, Division of Pediatric Cardiology, Lucile Packard Children's Hospital, 750 Welch Road, Suite no. 305, Palo Alto, CA 94304, United States of America. Tel: +1 650 498 4563; Fax: +1 650 725 8343; E-mail:
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1.C Apitz , GD Webb , AN Redington . Tetralogy of Fallot. Lancet 2009; 374: 14621471.

2.RJ Sommer , ZM Hijazi , JF Rhodes . Pathophysiology of congenital heart disease in the adult: part III: Complex congenital heart disease. Circulation 2008; 117: 13401350.

4.MD Pettersen , W Du , ME Skeens , RA Humes . Regression equations for calculation of z scores of cardiac structures in a large cohort of healthy infants, children, and adolescents: an echocardiographic study. J Am Soc Echocardiogr 2008; 21: 922934.

5.JT Flynn . Neonatal hypertension: diagnosis and management. Pediatr Nephrol 2000; 14: 332341.

6.S Oshita , R Uchimoto , H Oka , Y Saka , H Takeshita , N Funatsu . Correlation between arterial blood pressure and oxygenation in tetralogy of Fallot. J cardiothorac anesth 1989; 3: 597600.

7.RP Lasser , G Genkins . Effect of alterations in systemic pressure upon oxygen saturation in patients with congenital heart disease. Circulation research 1959; 7: 410416.

9.K Tanaka , H Kitahata , S Kawahito , J Nozaki , Y Tomiyama , S Oshita . Phenylephrine increases pulmonary blood flow in children with tetralogy of Fallot. Can J anaesth 2003; 50: 926929.

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Cardiology in the Young
  • ISSN: 1047-9511
  • EISSN: 1467-1107
  • URL: /core/journals/cardiology-in-the-young
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