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Temporary prolongation of the QT interval in acute ebastine intoxication due to challenge video on TikTok in a girl

Published online by Cambridge University Press:  07 December 2022

Sadiye Sert Open the ORCID record for Sadiye Sert [Opens in a new window]
Sadiye Sert*
Affiliation:
Department of Paediatrics, Konya Beyhekim Training and Research Hospital, Konya, Turkey
*
Author for correspondence: S. Sert, Beyhekim, Devlethane Sokak No:2/C, 42060, Konya, Turkey. Tel: + 90 332 2243000; Fax: + 90 332 263 12 45. E-mail: sadiyesert@yahoo.com.tr
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Abstract

Antihistamines are among the most widely used medications in the world. Ebastine is an antihistaminic which is long-acting, second-generation, and selective H1-receptor inverse agonist. I report a twelve-year-and-six-month-old girl with temporary prolongation of the QTc interval caused by acute ebastine intoxication due to TikTok challenge. Initial electrocardiogram showed sinus arrhythmia (72 beats/min) and prolongation of the QTc interval (QTc 482 milliseconds). Gastric lavage was performed. Intravenous fluid was administered, and activated charcoal (1 g/kg/per dose) was given. Electrocardiogram 9 h after drug ingestion showed sinus rhythm and normal QTc interval (QTc 414milliseconds). During follow-up, no electrocardiogram abnormalities were detected with electrocardiogram monitoring. She was discharged on day 2 without any complications. This case report is the first in the literature to show acute intoxication with ebastine due to challenge video on TikTok, which leads to a temporary prolongation of the QTc interval. Also, with this case report, I assert the fact that it is important to properly supervise the use of social media, such as TikTok and to review the content of TikTok videos.

Keywords

ChallengeEbastineIntoxicationQT intervalTikTok
Type
Brief Report
Information
Cardiology in the Young , Volume 33 , Issue 7 , July 2023 , pp. 1213 - 1216
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Copyright
© The Author(s), 2022. Published by Cambridge University Press

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