1.Sutula, TP, Hagen, J, Pitkänen, A. Do epileptic seizures damage the brain? Curr Opin Neural. 2003;16:189–195.
2.Buck, D, Baker, GA, Jacoby, A, Smith, DF, Chadwick, DW. Patients' experiences of injury as a result of epilepsy. Epilepsia. 1997;38:439–444.
3.Neufeld, MY, Vishne, T, Chistik, V, Korczyn, AD. Life-long history of injuries related to seizures. Epilepsy Res. 1999;34:123–127.
4.Beghi, E, Cornaggia, C. Morbidity and accidents in patients with epilepsy: results of a European cohort study. Epilepsia. 2002;43:1076–1083.
5.Morgan, CL, Kerr, MP. Epilepsy and mortality: a record linkage study in a U.K. population. Epilepsia. 2002;43:1251–1255.
6.Sperling, MR, Feldman, H, Kinman, J, Liporace, J, O'Connor MJ. Seizure control and mortality in epilepsy. Ann Neurol. 1999;46:45–50.
7.Tomson, T. Mortality in epilepsy. J Neurol. 2000;247:15–21.
8.Cockerell, OC, Johnson, AL, Sander, JW, Hart, YM, Goodridge, DMG, Shorvon, SD. Mortality from epilepsy: results from a prospective population-based study. Lancet. 1994;344:918–921.
9.Harvey, AS, Nolan, T, Carlin, JB. Community-based study of mortality in children with epilepsy. Epilepsia. 1993;34:597–603.
10.Strauss, DJ, Day, SM, Shavelle, RM, Wu, YW. Remote symptomatic epilepsy. Does seizure severity increase mortality? Neurology. 2003;60:395–399.
11.Klenerman, P, Sander, JW, Shorvon, SD. Mortality in patients with epilepsy: a study of patients in long-term residential care. J Neurol Neurosurg Psychiatry. 1993;56:149–152.
12.Nashef, L, Fish, DR, Garner, S, Sander, JW, Shorvon, SD. Sudden death in epilepsy: a study of incidence in a young cohort with epilepsy and learning difficulty. Epilepsia. 1995;36:1187–1194.
13.Sillanapaa, M, Jalava, M, Kaleva, O, Shinnar, S. Long-term prognosis of seizures with onset in childhood. N Engl J Med. 1998;338:1715–1722.
14.Nilsson, L, Farahmand, B, Persson, PG, Thiblin, I, Tomson, T. Risk factors for sudden, unexpected death in epilepsy—a case control study. Lancet. 1999;353:888–893.
15.Nashef, L, Fish, DR, Sander, JW, Shorvon, SD. Incidence of sudden unexpected death in an adult outpatient cohort with epilepsy at a tertiary referral centre. J Neurol Neurosurg Psychiatry. 1995;58:462–464.
16.Langan, Y, Nashef, L, Sander, JW. Certification of deaths attributable to epilepsy. J Neural Neurosurg Psychiatry. 2002;73:751–752.
17.Olafsson, E, Hauser, WA, Gudmundsson, G. Long-term survival of people with unprovoked seizures: a population-based study. Epilepsia. 1998;39:89–92.
18.Shackleton, DP, Westendorp, RG, Kasteleijn-Nolst Trenite, DG, de Craen, AJ, Vandenbroucke, JP. Survival of patients with epilepsy: an estimate of the mortality risk. Epilepsia. 2002;43:445–450.
19.Salanova, V, Markand, O, Worth, R. Temporal lobe epilepsy surgery: outcome, complications, and late mortality rate in 215 patients. Epilepsia. 2002;43:170–174.
20.Sutula, T, Pitkänen, A. Do seizures damage the brain? Prog Brain Res. 2002;135:133–138.
21.Kotloski, R, Lynch, M, Lauersdorf, S, et al.Repeated brief seizures induce progressive hippocampal neuron loss and memory deficits. Prog Brain Res. 2002;135:95–110.
22.Bengzon, J, Mohapel, P, Ekdahl, C, et al.Neuronal apoptosis after brief and prolonged seizures. Prog Brain Res 2002;135:111–119.
23.Salmenperä, T, Kälviäinen, R, Partanen, K, et al.Hippocampal and amygdaloid damage in partial epilepsy: a cross-sectional MRI study of 241 patients. Epilepsy Res. 2001;46:69–82.
24.Briellmann, R, Berkovic, S, Syngeniotis, A, et al.Seizure-associated hippocampal volume loss: a longitudinal magnetic resonance study of temporal lobe epilepsy. Ann Neurol. 2002;51:641–644.
25.Austin, J, Dunn, D. Progressive behavioral changes in children with epilepsy. Prog Brain Res. 2002;135:419–427.
26.Bjørnaes, H, Stabell, K, Henriksen, O, et al.The effects of refractory epilepsy on intellectual functioning in children and adults: a longitudinal study. Seizure. 2001;10:250–259.
27.Helmstaedter, C. Effects of chronic epilepsy on declarative memory systems. Prog Brain Res. 2002;135:439–453.
28.Hauser, WA, Lee, JR. Do seizures beget seizures? Prog Brain Res. 2002;135:215–219.
29.Dodrill, C, Batzel, L. Issues in quality of life assessment. In: Engel, J JrPedley, T, eds. Epilepsy: A Comprehensive Textbook. E. Washington Square, Penn: Lippincott-Raven Publishers; 1998:2227–2231.
30.McGlone, J. Memory complaints before and after temporal lobectomy: do they predict memory performance or lesion laterally? Epilepsia. 1994;35:529–539.
31.Perrine, K, Hermann, BP, Meador, KJ, et al.The relationship of neuropsychological functioning to quality of life in epilepsy. Arch Neurol. 1995;52:997–1003.
32.Johnson, V, Cho, R, Tracy, J, Glosser, D, Sperling, M. Determinants of quality of life in epilepsy. Neurology. 2002;58 (suppl 3):213.
33.Baker, G. Assessment of quality of life in people with epilepsy: some practical implications. Epilepsia. 2001;42:66–69.
34.Bishop, M, Allen, C. The impact of epilepsy on quality of life: a qualitative analysis. Epilepsy Behavr. 2003;4:226–233.
35.Berto, P. Quality of life in patients with epilepsy and impact of treatments. Pharmacoeconomics. 2002;20:1039–1059.
36.Birbeck, G, Hays, R, Cui, X, Vickrey, B. Seizure reduction and quality of life improvements in people with epilepsy. Epilepsia. 2002;43:535–538.
37.Devinsky, O. Psychosocial and behavioral function in epilepsy. In: Porter, R, Chadwick, D, eds. The Epilepsies. 2nd ed. Newton, Mass: Butterworth-Heinemann; 1997:347–363.
38.Collings, J. Life fulfilment in an epilepsy sample from the United States. Soc Sci Med. 1995;40:1579–1584.
39.Kellett, M, Smith, D, Backer, G, Chadwick, D. Quality of life after epilepsy surgery. J Neurol Neurosurg Psychiatry. 1997;63:52–58.
40.Suurmeijer, TP, Reuvekamp, MF, Aldenkamp, BP. Social functioning, psychological functioning, and quality of life in epilepsy. Epilepsia. 2001;42:1160–1168.
41.Vickrey, BG, Hays, RD, Engel, J Jret al.Outcome assessment for epilepsy surgery: the impact of measuring health related quality of life. Ann Neurol. 1995;37:158–166.
42.Weibe, S, Matijevic, S, Eliasziw, M, Derry, PA. Clinically important change in quality of life in epilepsy. J Neurol Neurosurg Psychiatry. 2002;73:116–120.
43.Hermann, B, Seidenberg, M, Bell, B, et al.The neurodevelopmental impact of childhood onset temporal lobe epilepsy on brain structure and function. Epilepsia. 2002;43:1062–1070.
44.Jokeit, H, Ebner, A. Effects of chronic epilepsy on intellectual functions. Prog Brain Res. 2002;135:455–463.
45.Neyens, L, Aldenkamp, A, Meinardi, H. Prospective follow-up of intellectual development in children with a recent onset of epilepsy. Epilepsy Res. 1999;34:85–90.
46.Huang, L, Yang, S, Liou, C, et al.Pentylenetetrazol-induced recurrent seizures in rat pups: time course on spatial learning and long-term effects. Epilepsia. 2002;43:567–573.
47.Lee, C, Hannay, J, Hrachovy, R, et al.Spatial learning deficits without hippocampal neuronal loss in a model of early-onset epilepsy. Neuroscience. 2001;107:71–84.
48.Prevey, M, Delaney, RJ, Cramer, R, Mattson, VA. Epilepsy Cooperative Study 264 Group. Complex partial and secondarily generalized seizure patients: cognitive functioning prior to treatment with antiepileptic medication. Epilepsy Res. 1998;30:1–9.
50.Hauser, W, Hesdorffer, D. Intellectual and psychological factors. In: Epilepsy: Frequency, Causes and Consequences. New York, NY: Demos Publications; 1990:245–271.
51.Taylor, D. Overview: psychiatric issues. In: Engel, J JrPedley, T, eds. Epilepsy: A Comprehensive Textbook. E. Washington Square, Penn: Lippincott-Raven Publishers; 1997:2039–2043.
52.Blumer, D, Altschuler, LL. Affective disorders. In: Engel, J JrPedley, T, eds. Epilepsy: A Comprehensive Textbook. E. Washington Square, Penn: Lippincott-Raven Publishers; 1997:2083–2124.
53.Tucker, GJ. Seizure disorders presenting with psychiatric symptomatology. Psychiatr Clin North Am. 1998;21:625–635.
54.Sperling, MR, O'Connor, MJ, Saykin, AJ, Plummer, C. Temporal lobectomy for refractory epilepsy. JAMA. 1996;276:470–475.
55.Batzel, L. Neuropsychological and emotional correlates of marriage and the ability to live independently in individuals with epilepsy. Epilepsia. 1984;25:594–598.
56.Callaghan, N, Crowley, M, Goggin, T. Epilepsy and employment, marital, education and social status. Ir Med J. 1992;85:17–19.
57.Carran, M, Kohler, C, O'Connor, MJ, Cloud, B, Sperling, MR. Marital status after epilepsy surgery. Epilepsia. 1999;40:1755–60.
58.Demerdash, A, Shaalan, M, Midani, A, Kamel, F, Bahri, M. Sexual behavior of a sample of females with epilepsy. Epilepsia. 1991;32:82–85.
59.Jacoby, A, Baker, BA, Steen, N, Potts, P, Chadwick, DW. The clinical course of epilepsy and its psychosocial correlates: findings from a UK community study. Epilepsia. 1996;37:148–161.
60.Seidenberg, M, Beck, N, Geisser, M, et al.Academic achievement of children with epilepsy. Epilepsia. 1986;27:753–759.
61.Suurmeijer, T. Treatment, seizure-free periods, and educational achievements: a follow-up study among children with epilepsy and healthy children. Fam Pract. 1991;8:320–328.
62.Zelnik, N, Sa'ado, L, Silman-Stolar, Z, Goikhman, I. Seizure control and educational outcome in childhood-onset epilepsy. J Child Neurol. 2001;16:820–824.
63.Kokkonen, J, Kokkonen, E, Saukkonen, A, Pennanen, P. Psychosocial outcome of young adults with epilepsy in childhood. J Neuro Neurosurg Psychiatry. 1997;62:265–268.
64.Shackleton, DP, Kasteleijn-Nolst Trenite, DG, De Craen, AJ, Vandenbroucke, JP, Westendorp, RG. Living with epilepsy: Long-term prognosis and psychosocial outcomes. Neurology. 2003;61:64–70.
65.The RESt-1 Group. Social aspects of epilepsy in the adult in seven European countries. Epilepsia. 2000;41:998–1004.
66.Sperling, MR, Saykin, A, Roberts, R, French, JA, O'Connor, MJ. Occupational outcome following temporal lobe surgery. J Epilepsy. 1994;7:144–151.
67.Jones, J, Berven, N, Ramirez, L, Woodard, A, Hermann, BP. Long-term psychosocial outcomes of anterior temporal lobectomy. Epilepsia. 2002;43:896–903.
68.Reeves, AL, So, E, Evans, RW, et al.Factors associated with work outcome after anterior temporal lobectomy for intractable epilepsy. Epilepsia. 1997;38:689–695.
69.Gilliam, F, Kuzniecky, R, Faught, E, Black, L, Carpenter, G, Schrodt, R. Patient-validated content of epilepsy-specific quality-of-life measurement. Epilepsia. 1997;38:233–236.