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Off-label prescribing: best practice or malpractice?


ISSUE:Standards for the practice of medicine are increasingly being confused with standards for the sale and reimbursement of medicines. Authority for prescribing of psychotropic drugs, whether on-label or off-label, is determined by the standard of medical care set by practitioners, not by regulators of the pharmaceutical industry.

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2. K Devulapalli , HA Nasrallah . An analysis of the high psychotropic off-label use in psychiatric disorders: the majority of psychiatric diagnoses have no approved drug. Asian J Psychiatr. 2009; 2: 2936.

3. DS Baldwin , N Kosky . Off label prescribing in psychiatric practice. Advances in Psychiatric Treatment. 2007; 13: 414422.

6. DC Radley , SN Finkelstein , RS Stafford . Off label prescribing among office-based physicians. Arch Intern Med. 2006; 166: 10211026.

11. SM Stahl . The tyranny of the majority and the interchangeability of drugs. Acta Psychiatrica Scand. 2013; 127: 45.

12. D Isaacs , D Fitzgerald . Seven alternatives to evidence based medicine. BMJ. 1999; 319: 7225.

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CNS Spectrums
  • ISSN: 1092-8529
  • EISSN: 2165-6509
  • URL: /core/journals/cns-spectrums
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