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Aerosol exposure of cattle to foot-and-mouth disease virus

Published online by Cambridge University Press:  19 October 2009

John W. McVicar  and
Robert J. Eisner
John W. McVicar
Affiliation:
Plum Island Animal Disease Center, USDA, ARS, S&E, P.O. Box 848, Greenport, New York 11944
Robert J. Eisner
Affiliation:
Plum Island Animal Disease Center, USDA, ARS, S&E, P.O. Box 848, Greenport, New York 11944
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Summary

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Slight modifications of a small, plastic covered greenhouse provided a chamber for the exposure of cattle of all ages to aerosols of foot-and-mouth disease virus. Particle size distributions of aerosols were 76% < 3 μm, 17% 3–6 μm, and 7% > 6 μm immediately after the deVilbis no. 40 nebulizer used was turned off and 90% < 3 μm, 8% 3–6 μm, and 2% > 6 μm 20–30 min later. Pharyngeal virus growth curves and viremia patterns correlated well with the dose of virus to which test cattle were exposed and were similar to those of cattle inoculated intranasally.

Type
Research Article
Information
Journal of Hygiene , Volume 91 , Issue 2 , October 1983 , pp. 319 - 328
Copyright
Copyright © Cambridge University Press 1983

References

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