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An investigation into the seroprevalence of Toxoplasma gondii, Bartonella spp., feline immunodeficiency virus (FIV), and feline leukaemia virus (FeLV) in cats in Addis Ababa, Ethiopia

  • N. TIAO (a1), C. DARRINGTON (a1), B. MOLLA (a1), W. J. A. SAVILLE (a1), G. TILAHUN (a2), O. C. H. KWOK (a3), W. A. GEBREYES (a1), M. R. LAPPIN (a4), J. L. JONES (a5) and J. P. DUBEY (a3)...
Summary
SUMMARY

Toxoplasma gondii and Bartonella spp. are zoonotic pathogens of cats. Feline immunodeficiency virus (FIV), and feline leukaemia virus (FeLV) are immunosuppressive viruses of cats that can affect T. gondii oocyst shedding. In this study, the prevalence of antibodies to T. gondii, Bartonella spp., FIV, as well as FeLV antigens were determined in sera from feral cats (Felis catus) from Addis Ababa, Ethiopia. Using the modified agglutination test, IgG antibodies to T. gondii were found in 41 (85·4%) of the 48 cats with titres of 1:25 in one, 1:50 in one, 1:200 in six, 1:400 in six, 1:800 in six, 1:1600 in eight, and 1:3200 in 13 cats. Toxoplasma gondii IgM antibodies were found in 11/46 cats tested by ELISA, suggesting recent infection. Antibodies to Bartonella spp. were found in five (11%) of 46 cats tested. Antibodies to FIV or FeLV antigen were not detected in any of the 41 cats tested. The results indicate a high prevalence of T. gondii and a low prevalence of Bartonella spp. infection in cats in Ethiopia.

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Corresponding author
*Author for correspondence: Dr J. P. Dubey, APDL, ANRI, BARC, Building 1001, USDA, Beltsville, MD 20705, USA. (Email: jitender.dubey@ars.usda.gov)
References
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1.Dubey JP. Toxoplasmosis of Animals and Humans, 2nd edn.Boca Raton: CRC Press, 2010, 313 pp.
2.Brunt J, et al. American Association of Feline Practitioners 2006 Panel report on diagnosis, treatment, and prevention of Bartonella spp. infections. Journal of Feline Medicine and Surgery 2006; 8: 213226.
3.Chomel BB, et al. Fatal case of endocarditis associated with Bartonella henselae type I infection in a domestic cat. Journal of Clinical Microbiology 2003; 41: 53375339.
4.Chomel BB, et al. Cat scratch diseas and other zoonotic Bartonella infections. Journal of the American Veterinary Medical Association 2004; 224: 12701279.
5.Lappin MR, et al. Prevalence of Bartonella species, Haemoplasma species, Ehrlichia species, Anaplasma phagocytophilum, and Neorickettsia risticii DNA in the blood of cats and their fleas in the United States. Journal of Feline Medicine and Surgery 2006; 8: 8590.
6.Lappin MR, Hawley J. Presence of Bartonella species and Rickettsia species DNA in the blood, oral cavity, skin and claw beds of cats in the United States. Veterinary Dermatology 2009; 20: 509514.
7.Varanat M, et al. Recurrent osteomyelitis in a cat due to infection with Bartonella vinsonii subsp. berkhoffii genotype II. Journal of Veterinary Internal Medicine 2009; 23: 12731277.
8.Breitschwerdt EB, et al. Bartonella species in blood of immunocompetent persons with animal and arthropod contact. Emerging Infectious Diseases 2007; 13: 938941.
9.Cutler S, et al. Bartonella quintana in Ethiopian lice. Comparative Immunology Microbiology and Infectious Diseases 2012; 35: 1721.
10.Mulugeta Y, et al. Ectoparasites of small ruminants in three selected agro-ecological sites of Tigray Region, Ethiopia. Tropical Animal Health Production 2010; 42: 12191224.
11.Dubey JP, Desmonts G. Serological responses of equids fed Toxoplasma gondii oocysts. Equine Veterinary Journal 1987; 19: 337339.
12.Lappin MR, et al. Diagnosis of recent Toxoplasma gondii infection in cats by use of an enzyme-linked immunosorbent assay for immunoglobulin M. American Journal of Veterinary Research 1989; 50: 15801585.
13.Lappin MR, et al. Prevalence of Bartonella species antibodies and Bartonella species DNA in the blood of cats with and without fever. Journal of Feline Medicine and Surgery 2009; 11: 141148.
14.Dubey JP. Feline toxoplasmosis and coccidiosis: a survey of domiciled and stray cats. Journal of the American Veterinary Medical Association 1973; 162: 873877.
15.Dubey JP, et al. Diagnosis of induced toxoplasmosis in neonatal cats. Journal of the American Veterinary Medical Association 1995; 207: 179185.
16.Omata Y, et al. Transfer of antibodies to kittens from mother cats chronically infected with Toxoplasma gondii. Veterinary Parasitology 1994; 52: 211218.
17.Dubey JP, Thulliez P. Serologic diagnosis of toxoplasmosis in cats fed Toxoplasma gondii tissue cysts. Journal of the American Veterinary Medical Association 1989; 194: 12971299.
18.Dubey JP, et al. Seroprevalence of Toxoplasma gondii and concurrent Bartonella spp., feline immunodeficiency virus, and feline leukemia infections in cats from Grenada, West Indies. Journal of Parasitology 2009; 95: 11291133.
19.Dubey JP, et al. Seroprevalence of Toxoplasma gondii and Bartonella spp. antibodies in cats from Pennsylvania. Journal of Parasitology 2009; 95: 578580.
20.Witt CJ, et al. Epidemiologic observations on feline immunodeficiency virus and Toxoplasma gondii coinfection in cats in Baltimore, MD. Journal of the American Veterinary Medical Association 1989; 194: 229233.
21.Childs JE, et al. Epidemiological observations on infection with Rochalimaea species among cats living in Baltimore, Md. Journal of the American Veterinary Medical Association 1994; 204: 17751778.
22.Al-Kappany YM, et al. Seroprevalence of Toxoplasma gondii and concurrent Bartonella spp., feline immunodeficiency virus, feline leukemia virus, and Dirofilaria immitis infections in Egyptian cats. Journal of Parasitology 2011; 97: 256258.
23.Barrs VR, et al. Prevalence of Bartonella species, Rickettsia felis, haemoplasmas, and the Ehrlichia group in the blood of cats and fleas in Eastern Australia. Australian Veterinary Journal 2010; 88: 160165.
24.Dubey JP, et al. A review of toxoplasmosis in humans and animals in Ethiopia. Epidemiology and Infection. Published online: 6 July 2012. doi:10.1017/S0950268812001392.
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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