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Analysis of a hepatitis C screening programme for US veterans

  • I. A. ZUNIGA (a1), J. J. CHEN (a1), D. S. LANE (a1), J. ALLMER (a2) and V. E. JIMENEZ-LUCHO (a2) (a3)
  • DOI: http://dx.doi.org/10.1017/S095026880500498X
  • Published online: 18 August 2005
Abstract

This study analyses a screening programme for hepatitis C virus (HCV) infection among US veterans in a suburban Veterans Affairs Medical Center, in New York. This is the first study examining all 11 potential risk factors listed in the 2001 National U.S. Veterans Health Administration Screening Guidelines. A retrospective study was conducted of 5400 veterans ‘at risk’ of HCV, identified through a questionnaire in this institution's primary-care outpatient departments between 1 October 2001 and 31 December 2003. Multivariate logistic regression models were built to identify independent predictors of infection. Of 2282 veterans tested for HCV, 4·6% were confirmed by HCV PCR to be HCV infected. In the multivariate model developed, injection drug use, blood transfusion before 1992, service during the Vietnam era, tattoo, and a history of abnormal liver function tests were independent predictors of HCV infection. Our data support considering a more targeted screening approach that includes five of the 11 risk factors.

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Corresponding author
Dept. of Preventive Medicine, HSC Level 3, Rm. 086, SUNY at Stony Brook, School of Medicine, Stony Brook, NY 11794-8036, USA. (Email: John.Chen@stonybrook.edu)
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This study was presented in part at the 2004 Annual Meeting of the Infectious Diseases Society of America in Boston, MA, USA.
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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