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    Cassini, A Colzani, E Kramarz, P Kretzschmar, ME and Takkinen, J 2016. Impact of food and water-borne diseases on European population health. Current Opinion in Food Science, Vol. 12, p. 21.


    Exum, Natalie G. Pisanic, Nora Granger, Douglas A. Schwab, Kellogg J. Detrick, Barbara Kosek, Margaret Egorov, Andrey I. Griffin, Shannon M. and Heaney, Christopher D. 2016. Use of Pathogen-Specific Antibody Biomarkers to Estimate Waterborne Infections in Population-Based Settings. Current Environmental Health Reports, Vol. 3, Issue. 3, p. 322.


    Kantsø, Bjørn Andersen, Anne-Marie Nybo Mølbak, Kåre Krogfelt, Karen Angeliki Henriksen, Tine Brink and Nielsen, Stine Yde 2014. Campylobacter, Salmonella, and Yersinia antibodies and pregnancy outcome in Danish women with occupational exposure to animals. International Journal of Infectious Diseases, Vol. 28, p. 74.


    Lopman, B. Simmons, K. Gambhir, M. Vinje, J. and Parashar, U. 2014. Epidemiologic Implications of Asymptomatic Reinfection: A Mathematical Modeling Study of Norovirus. American Journal of Epidemiology, Vol. 179, Issue. 4, p. 507.


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Campylobacter seroconversion rates in selected countries in the European Union

  • P. F. M. TEUNIS (a1) (a2), G. FALKENHORST (a3), C. W. ANG (a4), M. A. STRID (a3), H. DE VALK (a5), M. SADKOWSKA-TODYS (a6), L. ZOTA (a7), M. KUUSI (a8), M. C. ROTA (a9), J. B. SIMONSEN (a3), K. MØLBAK (a3), Y. T. H. P. VAN DUYNHOVEN (a1) and W. VAN PELT (a1)
  • DOI: http://dx.doi.org/10.1017/S0950268812002774
  • Published online: 11 December 2012
Abstract
SUMMARY

As a major foodborne pathogen, Campylobacter is frequently isolated from food sources of animal origin. In contrast, human Campylobacter illness is relatively rare, but has a considerable health burden due to acute enteric illness as well as severe sequelae. To study silent transmission, serum antibodies can be used as biomarkers to estimate seroconversion rates, as a proxy for infection pressure. This novel approach to serology shows that infections are much more common than disease, possibly because most infections remain asymptomatic. This study used antibody titres measured in serum samples collected from healthy subjects selected randomly in the general population from several countries in the European Union (EU). Estimates of seroconversion rates to Campylobacter were calculated for seven countries: Romania, Poland, Italy, France, Finland, Denmark and The Netherlands. Results indicate high infection pressures in all these countries, slightly increasing in Eastern EU countries. Of these countries, the differences in rates of notified illnesses are much greater, with low numbers in France and Poland, possibly indicating lower probability of detection due to differences in the notification systems, but in the latter case it cannot be excluded that more frequent exposure confers better protection due to acquired immunity.

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Corresponding author
*Author for correspondence: P. F. M. Teunis, Ph.D., National Institute of Public Health and the Environment, Centre for Infectious Disease Control, Anthonie van Leeuwenhoeklaan 9, 3721MA Bilthoven, The Netherlands. (Email: peter.teunis@rivm.nl)
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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