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Fülleborn, F.
1932.
Tropische Dermatosen Juxtaartikuläre Knoten Rattenbisskrankheit.
p.
708.
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A Case of Skin Infection with Ankylostoma
Published online by Cambridge University Press: 15 May 2009
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IN view of a previous failure1 to produce a skin infection with Ankylostoma, it seems worth while to put on record the present successful case. Dr J. B. Leathes very kindly offered himself as the subject of experiment. It is important to note that he has never, either before or during the course of the experiment, had anything to do with any Ankylosotoma material except that deliberately applied to his person for the purpose of this experiment, nor has he been to any infected place or even worked in the part of the Institute where the cultures of Ankylosotoma larvae have been kept. On March 21st a small quantity of water containing encapsuled larvae of A. duodenale, hatched artificially from infected faeces from Cornwall, and 13 days old, was applied to the forearm. After five minutes the arm was bandaged up and left for two hours, at the end of which time the wrappings were removed and the arm throughly cleansed. The purpose of the experiment and the precautions necessary were fully appreciated by the subject, and there is no doubt that there was not the slightest possibility of a mouth infection.
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References
page 280 note 1 This Journal, vol. IV. 1904, p. 89.
page 281 note 1 This Journal, vol. IV. 1904, p. 463Google Scholar
see also Smith, C. A, Journ. American Med. Association, vol. XLIII. 1904, p. 592.CrossRefGoogle Scholar
page 281 note 1 This Journal, vol. IV. 1904, p. 462.
page 283 note 1 The eosinophilia is extraordinarily persistent. A man who while infected showed 17–19 p.c. still has 11 p.c. though it is more than 30 months since treatment was commenced and fully 20 months since he was restored to health and his stools found to be free from ova on repeated examinations.
page 283 note 2 Communicated on behalf of Prof. Looss by Prof. Elliot Smith to the meeting of the British Medical Association at Oxford; see abstract in The Mining Journal, Aug. 6, 1904, p. 138.
page 283 note 3 Deutsche med. Wochenschr. 1904, p. 1338.Google Scholar
page 283 note 4 Journ. Amer. Med. Assoc. vol. XLIII. 1904, p. 592.CrossRefGoogle Scholar
page 283 note 5 Bull. de l'acad. Roy. de Méd. de Belgique, Jan. 28, 1905.Google Scholar
Smith, F, Journ. Roy. Army Med. Corps, vol. IV. 1905, p. 335.Google Scholar
Liefmann, H, Zeitschr. für Hygiene, vol. L. 1905, p. 349, have also recorded successful skin infections in dogs with A. caninum.CrossRefGoogle Scholar
page 283 note 6 Acad. Roy. de Méd. de Belgique, procès-verbal, Jan. 28. 1905, p. 8.Google Scholar
page 283 note 7 Journ. American Med. Association, Sep. 19, 1903.Google Scholar
page 283 note 8 Report on Anaemia in Porto Rico, San Juan, 1904. This valuable report shows in a striking manner the fearful havoc which Ankylostoma can play in a bare-footed and untreated population. A large proportion of the natives seem to have less than 50 p.c. haemoglobin.
page 284 note 1 A. Manouvriez, De l'anémie des mineurs, dite d'anzin, Valenciennes, 1878. See also De l'anémie ankylostomiasique des mineurs, Valenciennes, 1904.
page 284 note 2 It has been previously pointed out (This Journal, vol. III. 1903, p. 109), that attacks of urticaria, like the general pruritus, may also occur long after the patient is removed from any possibility of fresh infection. See also Journ. Roy. Army Med. Corps, vol. IV. 1905, p. 652.
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