Skip to main content
    • Aa
    • Aa
  • Get access
    Check if you have access via personal or institutional login
  • Cited by 4
  • Cited by
    This article has been cited by the following publications. This list is generated based on data provided by CrossRef.

    Cutts, Felicity T. and Hanson, Matt 2016. Seroepidemiology: an underused tool for designing and monitoring vaccination programmes in low- and middle-income countries. Tropical Medicine & International Health, Vol. 21, Issue. 9, p. 1086.

    Dimech, Wayne and Mulders, Mick N. 2016. A 16-year review of seroprevalence studies on measles and rubella. Vaccine, Vol. 34, Issue. 35, p. 4110.

    Lin, Yu-Chun Hsieh, Yu-Chia Huang, Ya-Ling Huang, Yu-Chiau Hung, Yung-Tai and Huang, Yhu-Chering 2016. Seroepidemiology for measles among elementary school children in Northern Taiwan. Journal of Microbiology, Immunology and Infection, Vol. 49, Issue. 4, p. 561.

    Fiebelkorn, Amy Parker Seward, Jane F. and Orenstein, Walter A. 2014. A global perspective of vaccination of healthcare personnel against measles: Systematic review. Vaccine, Vol. 32, Issue. 38, p. 4823.


Changes in measles seroepidemiology of healthcare workers in southern Taiwan

  • T. S. HO (a1), S. M. WANG (a1), L. R. WANG (a2) and C. C. LIU (a2) (a3)
  • DOI:
  • Published online: 14 April 2011

To assess the measles seroepidemiology of healthcare workers (HCWs), from 2004 to 2009 all newly recruited staff at a university hospital in Taiwan, were tested for specific immunoglobulin G antibodies for measles virus using enzyme-linked immunosorbent assays. A total of 1584 HCWs were included. The positivity rate of measles antibody for physicians and nurses was about 90%. The positivity of measles antibody in different age groups was 78·1%, 93·9% and 94·2% for 20–29, 30–39 and ⩾40 years age groups, respectively. Equivocal results were more frequent in the 20–29 (17·1%) years age group. A lack of antibody against measles was reported for 66 (4·2%) of those tested. Medical student (8·3%) and housekeeping personnel (5·3%) had the greatest lack of antibodies. This study demonstrates the waning measles immunity in younger HCWs in Taiwan, which poses the potential risk of nosocomial transmission of measles. Periodic surveillance and revaccination of susceptible HCWs is recommended.

Corresponding author
*Author for correspondence: Dr C. C. Liu, Department of Paediatrics, National Cheng Kung University Medical College and Hospital, No.138, Sheng-Li Road, Tainan 704, Taiwan. (Email: [C. C. Liu]
(Email: [S. M. Wang]
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

2.P Godoy , Measles epidemiology in Catalonia (Spain): implications for a regional vaccination programme. International Journal of Epidemiology 1999; 28: 558562.

6.MS Lee , Seroepidemiology and evaluation of passive surveillance during 1988–1989 measles outbreak in Taiwan. International Journal of Epidemiology 1992; 21: 11651174.

8.WY Cheng , Molecular evolution of measles viruses circulated in Taiwan 1992–2008. Virology Journal 2009; 6: 219.

12.GM Mendelson , Nosocomial transmission of measles to healthcare workers. Time for a national screening and immunization policy for NHS staff? Journal of Hospital Infection 2000; 44: 154155.

14.WL Atkinson , Transmission of measles in medical settings – United States, 1985–1989. American Journal of Medicine 1991; 91: 320S324S.

15.RM Davis , Transmission of measles in medical settings: 1980 through 1984. Journal of American Medical Association 1986; 255: 12951298.

20.MS Lee , Measles seroepidemiology and decay rate of vaccine-induced measles IgG titers in Taiwan, 1995–1997. Vaccine 2001; 19: 46444651.

21.LC McDonald , SARS in healthcare facilities, Toronto and Taiwan. Emerging Infectious Diseases 2004; 10: 777781.

22.SS Yalcin , G Kanra , T Pehlivan . Outbreak of measles in medical students and determination of immune status to measles-mumps-rubella viruses. International Journal of Adolescent Medicine and Health 2006; 18: 615622.

23.S Wicker , Seroprevalence of vaccine preventable and blood transmissible viral infections (measles, mumps, rubella, polio, HBV, HCV and HIV) in medical students. Medical Microbiology and Immunology 2007; 196: 145150.

24.CJ Williams , Low measles, mumps and rubella (MMR) vaccine uptake in hospital healthcare worker contacts following suspected mumps infection. Journal of Hospital Infection 2010; 76: 9192.

25.A Tischer , E Gerike . Immune response after primary and re-vaccination with different combined vaccines against measles, mumps, rubella. Vaccine 2000; 18: 13821392.

27.IJ Amanna , NE Carlson , MK Slifka . Duration of humoral immunity to common viral and vaccine antigens. New England Journal of Medicine 2007; 357: 19031915.

28.MS Dine , Persistence of vaccine-induced antibody to measles 26–33 years after vaccination. Journal of Infectious Diseases 2004; 189: S123S130.

29.I Davidkin , Persistence of measles, mumps, and rubella antibodies in an MMR-vaccinated cohort: a 20-year follow-up. Journal of Infectious Diseases 2008; 197: 950956.

31.U Fedeli , C Zanetti , B Saia . Susceptibility of healthcare workers to measles, mumps, rubella and varicella. Journal of Hospital Infection 2002; 51: 133135.

32.MA Almuneef , Seroprevalence survey of varicella, measles, rubella, and hepatitis A and B viruses in a multinational healthcare workforce in Saudi Arabia. Infection Control and Hospital Epidemiology 2006; 27: 11781183.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *