Skip to main content Accessibility help
×
Home

Contribution of RSV to bronchiolitis and pneumonia-associated hospitalizations in English children, April 1995–March 1998

  • B. MÜLLER-PEBODY (a1) (a2), W. J. EDMUNDS (a1), M. C. ZAMBON (a3), N. J. GAY (a1) and N. S. CROWCROFT (a1)...

Abstract

Estimates of the number of hospitalizations attributable to specific pathogens are required to predict the potential impact of vaccination. All hospital admissions for lower respiratory tract infection (LRI) in children <5 years in England in 1995–8 were reviewed. Most admissions (76.8%) were not associated with specific organisms. Seasonality in pathogens that cause bronchiolitis and pneumonia was used to predict the proportion of cases with unspecified aetiology attributable to different organisms using multiple linear regression. Of 12298 admissions for LRI, 17.5% were due to RSV infection. An estimated 74.8% (95% CI, 72.0–77.7%) of ‘unspecified bronchiolitis’ admissions and 16.3% (95% CI, 13.7–18.8%) of ‘unspecified pneumonia’ admissions were RSV related. The total mean annual incidence of hospital admissions attributable to RSV is 28.3/1000 children <1 year of age, and 1.3/1000 children 1–4 years old. The greater burden of RSV infection than indicated through discharge data is revealed through applying simple statistical methods.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Contribution of RSV to bronchiolitis and pneumonia-associated hospitalizations in English children, April 1995–March 1998
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Contribution of RSV to bronchiolitis and pneumonia-associated hospitalizations in English children, April 1995–March 1998
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Contribution of RSV to bronchiolitis and pneumonia-associated hospitalizations in English children, April 1995–March 1998
      Available formats
      ×

Copyright

Corresponding author

Author for correspondence.

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed