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Cost-effectiveness of interferon-gamma release assay for entry tuberculosis screening in prisons

  • A. KOWADA (a1)
Abstract
SUMMARY

The incidence of active tuberculosis (TB) and latent tuberculosis infection (LTBI) in inmates and prison staff is higher than that in the general population. Mycobacterium tuberculosis-specific interferon-gamma release assays (IGRAs) provide more accurate diagnosis of M. tuberculosis infection with higher specificity than the tuberculin skin test (TST). To assess the cost-effectiveness of QuantiFERON®-TB Gold In-Tube (QFT) compared to TST, TST followed by QFT and chest X-ray, we constructed Markov models using a societal perspective on the lifetime horizon. The main outcome measure of effectiveness was quality-adjusted life-years (QALYs) gained. The incremental cost-effectiveness was compared. The QFT-alone strategy was the most cost-effective for entry TB screening in prisons in developed countries. Cost-effectiveness was not sensitive to the rates of BCG vaccination, LTBI, TB, HIV infection and multidrug-resistant TB. Entry TB screening using an IGRA in prisons should be considered on the basis of its cost-effectiveness by public health intervention.

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*Address for correspondence: Dr A. Kowada, Kojiya Haneda Healthcare Service, Ota City Public Health Office, Tokyo, Japan. (Email: kowadaa@gmail.com)
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2. JA Bick . Infection control in jails and prisons. Clinical Infectious Disease 2007; 45: 10471055.

3. A Kariminia , Factors associated with mortality in a cohort of Australian prisoners. European Journal of Epidemiology 2007; 22: 417428.

4. CR Horsburgh Jr., EJ Rubin . Clinical practice. Latent tuberculosis infection in the United States. New England Journal of Medicine 2011; 364: 14411448.

5. DS Abebe , Prevalence of pulmonary tuberculosis and associated risk factors in Eastern Ethiopian prisons. International Journal of Tuberculosis and Lung Disease 2011; 15: 668673.

6. D Stuckler , Mass incarceration can explain population increases in TB and multidrug-resistant TB in European and central Asian countries. Proceedings of the National Academy of Sciences USA 2008; 105: 1328013285.

7. K Lönnroth , Tuberculosis control and elimination 2010–50: cure, care, and social development. Lancet 2010; 375: 18141829.

8. MC Layton , Universal radiographic screening for tuberculosis among inmates upon admission to jail. American Journal of Public Health 1997; 87: 13351337.

9. A Kowada . Cost effectiveness of interferon-gamma release assay for school-based tuberculosis screening. Molecular Diagnosis and Therapy 2012; 16: 181190.

10. MA de Perio , Cost-effectiveness of interferon gamma release assays vs tuberculin skin tests in health care workers. Archives of Internal Medicine 2009; 169: 179187.

11. A Kowada , Cost-effectiveness analysis of interferon-γ release assays versus chest X-ray for annual tuberculosis screening of healthcare workers. Journal of Hospital Infection 2011; 78: 152154.

12. A Kowada . Cost-effectiveness of interferon-γ release assay versus chest X-ray for tuberculosis screening of employees. American Journal of Infection Control 2011; 39: e6772.

13. A Kowada . Cost effectiveness of interferon-gamma release assay for tuberculosis screening of rheumatoid arthritis patients prior to initiation of tumor necrosis factor-α antagonist therapy. Molecular Diagnosis and Therapy 2010; 14: 367373.

14. AB Hardy , Cost-effectiveness of the NICE guidelines for screening for latent tuberculosis infection: the QuantiFERON-TB Gold IGRA alone is more cost-effective for immigrants from high burden countries. Thorax 2010; 65: 178180.

16. M Pai , A Zwerling , D Menzies . Systematic review: T-cell-based assays for the diagnosis of latent tuberculosis infection: an update. Annals of Internal Medicine 2008; 149: 177184

17. P Tattevin , The validity of medical history, classic symptoms, and chest radiographs in predicting pulmonary tuberculosis: derivation of a pulmonary tuberculosis prediction model. Chest 1999; 115: 12481253.

18. R Cohen , The validity of classic symptoms and chest radiographic configuration in predicting pulmonary tuberculosis. Chest 1996; 109: 420423.

22. CB Chee , Tuberculosis treatment effect on T-cell interferon-gamma responses to Mycobacterium tuberculosis-specific antigens. European Respiratory Journal 2010; 36: 355361.

25. SC Resch , Cost-effectiveness of treating multidrug-resistant tuberculosis. PLoS Medicine 2006; 3: e241.

26. CA Marra , Health-related quality of life trajectories among adults with tuberculosis: differences between latent and active infection. Chest 2008; 133: 396403.

27. I Baussano , Tuberculosis incidence in prisons: a systematic review. PLoS Medicine 2010; 7: e1000381.

28. AA Reichard , Assessment of tuberculosis screening and management practices of large jail systems. Public Health Reports 2003; 118: 500507.

29. D Lee , Global fund financing of tuberculosis services delivery in prisons. Journal of Infectious Diseases 2012; 205: S274283.

30. SE Reid , Tuberculosis and HIV control in sub-Saharan African prisons: ‘thinking outside the prison cell’. Journal of Infectious Diseases 2012; 205: S265273.

33. TF Jones , W Schaffner . Miniature chest radiograph screening for tuberculosis in jails: a cost-effectiveness analysis. American Journal of Respiratory and Critical Care Medicine 2001; 164: 7781.

35. CR Horsburgh Jr.. Priorities for the treatment of latent tuberculosis infection in the United States. New England Journal of Medicine 2004; 350: 20602067.

38. D Menzies , Adverse events with 4 months of rifampin therapy or 9 months of isoniazid therapy for latent tuberculosis infection: a randomized trial. Annals of Internal Medicine 2008; 149: 689697.

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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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