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The development of TRIC organisms in cell cultures during multiple infection

Published online by Cambridge University Press:  15 May 2009

Andrea Evans
Andrea Evans
Affiliation:
Medical Research Council Trachoma Unit, Lister Institute of Preventive Medicine, London SW 1
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Summary

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The relationship between multiplicity of infection and the yield of organisms and of polysaccharide was studied in BHK 21 cells infected with TRIC organisms. Although an increase in themultiplicity of infection resulted in an increase in the absolute number of organisms per culture, there was a decrease in relation to the number of infecting organisms. The amount of polysaccharide produced was independent of multiplicity of infection; it was not limited by the concentration of glucose in the medium. Polysaccharide leaked from cells and was slowly broken down in the culture medium.

Type
Research Article
Information
Journal of Hygiene , Volume 70 , Issue 1 , March 1972 , pp. 39 - 48
Copyright
Copyright © Cambridge University Press 1972

References

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