Skip to main content
×
Home
    • Aa
    • Aa

Epidemiology of Pseudomonas aeruginosa keratitis in contact lens wearers

  • F. Stapleton (a1) (a2) (a3), J. K. G. Dart (a2) (a3), D. V. Seal (a2) (a4) and M. Matheson (a2) (a3)
Abstract
SUMMARY

This study evaluated the epidemiology of Pseudomonas aeruginosa keratitis in contact lens (CL) wearers; the relationships between CL storage case contamination and CL hygiene practice and between CL hygiene and the development of keratitis. Sixteen CL wearers with keratitis were compared with 44 asymptomatic controls. Lens hygiene practice was assessed and CL care materials, domestic water sites and endogenous sites were evaluated microbiologically. Poor CL hygiene was not associated with Ps. aeruginosa keratitis. There was an association between keratitis and bacterial contamination of the CL and storage case (P < 0·0005). Lens and storage case contamination were not significantly associated with poor hygiene. No domestic or endogenous source for Ps. aeruginosa was found. Causative organisms may be derived from other sources, but CLs and CL storage cases provide a favourable environment for Ps. aeruginosa colonization. Changing the CL care environment to one less favourable for Ps. aeruginosa may help to eliminate this problem.

Copyright
Corresponding author
* For correspondence.
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1.DC Musch , A Sugar , RF Meyer . Demographic and predisposing factors in corneal ulceration. Arch Ophthalmol 1983; 101: 1545–8.

2.JKG Dart , F Stapleton , D Minassian . Contact lenses and other risk factors in microbial keratitis. Lancet 1991; 338: 650–3.

3.PR Laibson , ED Donnenfield . Corneal ulcers related to contact lens use. Int Ophthalmol Clin 1986; 26: 314.

4.A Koidou-Tsiligianni , E Alfonso , RK Forster . Ulcerative keratitis associated with contact lens wear. Am J Ophthalmol 1989; 108: 64–7.

5.OD Schein , LD Ormerod , Barraquer Microbiology of contact lens-related ulcers. Cornea 1989; 8: 281–5.

6.JH Lass , J Haaf , CS Foster , C Belcer . Visual outcome in eight cases of Serratia marcescens keratitis. Am J Ophthalmol 1981; 92: 384–90.

7.E Alfonso , S Mandelbaum , MJ Fox , RK Forster . Ulcerative keratitis associated with contact lens wear. Am J Ophthalmol 1984; 101: 429–33.

8.LA Wilson , RL Schlitzer , DG Ahern . Pseudomonas corneal ulcers associated with soft contact lens wear. Am J Ophthalmol 1981; 92: 546–54.

9.LD Ormerod , RE Smith . Contact lens-associated microbial keratitis. Arch Ophthalmol 1986; 104: 7983.

11.AK Bates , RJ Morris , F Stapleton , DC Minassian , JKG Dart . ‘Sterile’ corneal infiltrates in contact lens wearers. Eye 1989; 3: 803–10.

12.DV Seal , F Stapleton , JK Dart . Possible sources of Acanthamoeba in contact lens wearers. Br J Ophthalmol 1992; 76: 424–7.

13.OD Schein , RJ Glynn , EC Poggio , JM Seddon , Kenyon KR and the Microbial Keratitis Study Group. The relative risk of ulcerative keratitis among users of daily-wear and extended-wear soft contact lenses. New Engl J Med 1989; 321: 773–8.

14.BJ Mondino , BA Weissman , D Farb , TH Pettit . Corneal ulcers associated with daily wear and extended wear contact lenses. Am J Ophthalmol 1986; 102: 5865.

15.LA Wilson , AD Sawant , RB Simmons , DG Ahern . Microbial contamination of contact lens storage cases and solutions. Am J Ophthalmol 1990; 110: 193–8.

16.PB Donzis , BJ Mondino , BA Weissman , DA Bruckner . Microbial contamination of contact lens care systems. Am J Ophthalmol 1987; 104: 325–33.

17.DFP Larkin , S Kilvington , DL Easty . Contamination of contact lens storage cases by Acanthamoeba and bacteria. Br J Ophthalmol 1990; 74: 133–5.

19.JA Duran , MF Refojo , IK Gipson , KR Kenyon . Pseudomonas attachment to new hydrogel contact lenses. Arch Ophthalmol 1987; 105: 106–9.

21.JW Costerton , RT Irvin . The bacterial glycocalyx in nature and disease. Ann Rev Microbiol 1981: 35: 299324.

22.LA Wilson , AD Sawant , DG Ahern . Comparative efficacies of soft contact lens disinfectant solutions against microbial films in lens cases. Arch Ophthalmol 1991; 109: 1155–7.

24.G Smolin . The microbial flora in extended wear soft contact lens wearers. Am J Ophthalmol 1979; 88: 543–7.

26.J Morgan . Complications associated with contact lens solutions. Ophthalmology 1979; 86: 1107–19.

27.G Hovding . The conjunctival and contact lens bacterial flora during lens wear. Acta Ophthalmol 1981; 59: 387401.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×