Hostname: page-component-8448b6f56d-m8qmq Total loading time: 0 Render date: 2024-04-23T17:09:12.927Z Has data issue: false hasContentIssue false
  • English
  • Français

The isolation of fusobacteria from tropical ulcers

Published online by Cambridge University Press:  19 October 2009

B. Adriaans  and
B. S. Drasar
B. Adriaans
Affiliation:
London School of Hygiene and Tropical Medicine, University of London, Keppel Street, London WC1E 7HT
B. S. Drasar
Affiliation:
London School of Hygiene and Tropical Medicine, University of London, Keppel Street, London WC1E 7HT
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Tropical ulcer is a disease found most commonly in the tropics, although the disease is not confined to those areas. Young children are affected most frequently and the disease is thought to be a polymicrobial infection with fusobacteria, aerobic microorganisms and spirochaetes each playing a role. The fusobacteria have been reported on smears but have not been cultured thus far. We report the isolation and culture of these organisms from 46 ulcers and have also demonstrated the same organisms in skin biopsies from these lesions.

Type
Research Article
Information
Epidemiology & Infection , Volume 99 , Issue 2 , October 1987 , pp. 361 - 372
Copyright
Copyright © Cambridge University Press 1987

References

REFERENCES

Adriaans, B., Hay, R. J., Drasar, B. S. & Robinson, D. C. (1986). Anaerobic bacteria in tropical ulcer – the application of a new transport system for their isolation. Transactions of the Royal Society of Tropical Medicine and Hygiene 80, 793–794.CrossRefGoogle ScholarPubMed
Adriaans, B., Hay, R. J., Lucas, S. & Robinson, D. C. (1987). The light and electron microscopic findings of tropical ulcers. Journal of Clinical Pathology (In the Press.)CrossRefGoogle Scholar
Adriaans, B., Hay, R. J., Drasar, B. S. & Robinson, D. C. (1987). The infectious aetiology of tropical ulcer – a study of the role of anaerobic bacteria. British Journal of Dermatology 116, 31–37.Google Scholar
Bennett, K. & Duerden, B. I. (1985). The identification of Fusobacteria in a routine diagnostic laboratory. Journal of Applied Bacteriology 59, 171–181.CrossRefGoogle Scholar
Clements, F. N. (1936). Tropical ulcer with special reference to its aetiology. Medical Journal of Australia 2, 615–644.Google Scholar
Cowan, S. T. (1974). Cowan & Steel's Manual for the Identification of Medical Bacteria, 2nd edn, p. 167. London: Cambridge University Press.Google Scholar
Duerden, B., Holbrook, W. P., Collee, J. G. & Watt, B. (1976). The characterisation of clinically important gram-negativo anaerobic bacilli by conventional bacteriological tests. Journal of Applied Bacteriology 40, 163–188.Google Scholar
Finegold, S. M. (1977). Anaerobic Bacteria in Human Disease, p. 394. London and New York: Academic Press.Google Scholar
Holdeman, L. V., Moore, W. E. C. & Cato, E. (1977). Anaerobe Laboratory Manual, 4th edn.Blacksburg, VA: Virginia Polytechnic Institute and State University.Google Scholar
Kelly, R. (1971). Cultivation of Borrelia hermsi. Science 173, 443–444.Google Scholar
Leschine, S. B. & Canale-Parola, E. (1980). Rifampicin as a selective agent for isolation of oral spirochaetes. Journal of Clinical Microbiology 12, 792–795.CrossRefGoogle Scholar
Lindner, R. R. & Adeniyi-Jones, C. (1952). The effect of metronidazole on tropical ulcers. Transactions of the Royal Society of Tropical Medicine and Hygiene 62, 712–715.CrossRefGoogle Scholar
Lowenthal, L. J. (1963). Tropical phagedenic ulcer; a review. International Review of Tropical Medicine 2, 267–291.Google Scholar
Moore, W. E. C., Hash, D. E., Holdeman, L. V. & Cato, E. P. (1980). Polyacrylamide slab gel electrophoresis of soluble proteins for studies of bacterial floras. Applied and Environmental Microbiology 39, 900–907.CrossRefGoogle ScholarPubMed
Moore, W. E. C., Holdeman, L. V., Smibert, R. M., Cato, E. P., Burmeister, J. A., Palcanis, K. G. & Ranney, R. R. (1984). Bacteriology of experimental gingivitis in children. Infection and Immunity 46, 1–6.CrossRefGoogle ScholarPubMed
Ninomiya, K., Ohtani, F. & Koosaka, S. (1972). Simple and expedient methods of differentiation among Bacteroides, Sphaerophorus and Fusobacterium. Japanese Journal of Medical Science and Biology 25, 63–73.CrossRefGoogle ScholarPubMed
Roberts, D. S. & Egerton, J. R. (1969). The aetiology and pathogenesis of ovine footrot. II. The pathogenic association of Fusiformis nodosus and F. necrophonis. Journal of Comparative Pathology 79, 217–227.CrossRefGoogle Scholar
Robinson, D. A. & Hay, R. J. (1985). Tropical ulcer in Zambia. Transactions of the Royal Society of Tropical Medicine and Hygiene 80, 132–137.CrossRefGoogle Scholar