Reed, G, et al.
Epidemiology and clinical impact of parainfluenza virus infections in otherwise healthy infants and young children <5 years old. Journal of Infectious Diseases
1997; 175: 807–813.
Nair, H, et al.
Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet
2010; 375: 1545–1555.
Nair, H, et al.
Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis. Lancet
2011; 378: 1917–1930.
Juzeniene, A, et al.
The seasonality of pandemic and non-pandemic influenzas: the roles of solar radiation and vitamin D. International Journal of Infectious Diseases
2010; 14: e1099–1105.
Shek, LP, Lee, BW. Epidemiology and seasonality of respiratory tract virus infections in the tropics. Paediatric Respiratory Reviews
2003; 4: 105–111.
Hope-Simpson, RE. The role of season in the epidemiology of influenza. Journal of Hygiene
1981; 86: 35–47.
Hayes, DP. Influenza pandemics, solar activity cycles, and vitamin D. Impact of vitamin D administration on immunogenicity of trivalent inactivated influenza vaccine in previously unvaccinated children. Medical Hypotheses
2010; 74: 831–834.
Holick, MF. Vitamin D: a d-lightful solution for health. Journal of Investigative Medicine
2011; 59: 872–880.
Kazantzidis, A, et al.
Calculations of the human vitamin D exposure from UV spectral measurements at three European stations. Photochemical and Photobiological Sciences
2009; 8: 45–51.
Diffey, BL. Modelling vitamin D status due to oral intake and sun exposure in an adult British population. British Journal of Nutrition
2013; 110: 569–577.
Kasahara, AK, Singh, RJ, Noymer, A. Vitamin D (25OHD) Serum Seasonality in the United States. PLoS One
2013; 8: e65785.
Fraser, WD, Milan, AM. Vitamin D assays: past and present debates, difficulties, and developments. Calcified Tissue International
2013; 92: 118–127.
Cranney, A, et al.
Effectiveness and safety of vitamin D in relation to bone health. Evidence Report/Technology Assessment (Full Report)
2007; 158: 1–235.
Ross, AC, et al. (eds). Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press, 2011.
Heaney, RP. Assessing vitamin D status. Current Opinion in Clinical Nutrition & Metabolic Care
2011; 14: 440–444.
Kreijtz, JH, Fouchier, RA, Rimmelzwaan, GF. Immune responses to influenza virus infection. Virus Research
2011; 162: 19–30.
Nakano, M, et al.
Type I interferon induces CX3CL1 (fractalkine) and CCL5 (RANTES) production in human pulmonary vascular endothelial cells. Clinical and Experimental Immunology
2012; 170: 94–100.
Milde, P, et al.
Expression of 1,25-dihydroxyvitamin D3 receptors in normal and psoriatic skin. Journal of Investigative Dermatology
1991; 97: 230–239.
Kresfelder, TL, et al.
Confirmation of an association between single nucleotide polymorphisms in the VDR gene with respiratory syncytial virus related disease in South African children. Journal of Medical Virology
2011; 83: 1834–1840.
Beard, JA, Bearden, A, Striker, R. Vitamin D and the anti-viral state. Journal of Clinical Virology
2011; 50: 194–200.
Barlow, PG, et al.
Antiviral activity and increased host defense against influenza infection elicited by the human cathelicidin LL-37. PLoS One
2011; 6: e25333.
Cannell, JJ, et al.
Epidemic influenza and vitamin D. Epidemiology and Infection
2006; 134: 1129–1140.
Tumpey, TM, et al.
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice. Journal of Virology
2005; 79: 14933–14944.
Khare, D, et al.
Calcitriol [1,25[OH]2D3] pre- and post-treatment suppresses inflammatory response to influenza A (H1N1) infection in human lung A549 epithelial cells. European Journal of Nutrition
2013; 52: 1405–1415.
Zhou, Z, et al.
Autophagy is involved in influenza A virus replication. Autophagy
2009; 5: 321–328.
Khoo, AL, et al.
Regulation of cytokine responses by seasonality of vitamin D status in healthy individuals. Clinical and Experimental Immunology
2011; 164: 72–79.
Enioutina, EY, Bareyan, D, Daynes, RA. TLR ligands that stimulate the metabolism of vitamin D3 in activated murine dendritic cells can function as effective mucosal adjuvants to subcutaneously administered vaccines. Vaccine
2008; 26: 601–613.
Hansdottir, S, et al.
Vitamin D decreases respiratory syncytial virus induction of NF-kappaB-linked chemokines and cytokines in airway epithelium while maintaining the antiviral state. Journal of Immunology
2010; 184: 965–974.
de Jong, MD, et al.
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nature Medicine
2006; 12: 1203–1207.
Staeva-Vieira, TP, Freedman, LP. 1,25-dihydroxyvitamin D3 inhibits IFN-gamma and IL-4 levels during in vitro polarization of primary murine CD4+ T cells. Journal of Immunology
2002; 168: 1181–1189.
Froicu, M, et al.
A crucial role for the vitamin D receptor in experimental inflammatory bowel diseases. Molecular Endocrinology
2003; 17: 2386–2392.
Bruce, D, et al.
Converging pathways lead to overproduction of IL-17 in the absence of vitamin D signaling. International Immunology
2011; 23: 519–528.
Kang, SW, et al.
1,25-Dihyroxyvitamin D3 promotes FOXP3 expression via binding to vitamin D response elements in its conserved noncoding sequence region. Journal of Immunology
2012; 188: 5276–5282.
Urry, Z, et al.
The role of 1alpha,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+ and IL-10+ CD4+ T cells. European Journal of Immunology
2012; 42: 2697–2708.
Gorman, S, Judge, MA, Hart, PH. Topical 1,25-dihydroxyvitamin D3 subverts the priming ability of draining lymph node dendritic cells. Immunology
2010; 131: 415–425.
Antunes, I, Kassiotis, G. Suppression of innate immune pathology by regulatory T cells during influenza A virus infection of immunodeficient mice. Journal of Virology
2010; 84: 12564–12575.
Najada, AS, Habashneh, MS, Khader, M. The frequency of nutritional rickets among hospitalized infants and its relation to respiratory diseases. Journal of Tropical Pediatrics
2004; 50: 364–368.
Wayse, V, et al.
Association of subclinical vitamin D deficiency with severe acute lower respiratory infection in Indian children under 5 y. European Journal of Clinical Nutrition
2004; 58: 563–567.
Roth, DE, et al.
Vitamin D status is not associated with the risk of hospitalization for acute bronchiolitis in early childhood. European Journal of Clinical Nutrition
2009; 63: 297–299.
Ginde, AA, Mansbach, JM, Camargo, CA. Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. Archives of Internal Medicine
2009; 169: 384–390.
Roth, DE, et al.
Vitamin D status and acute lower respiratory infection in early childhood in Sylhet, Bangladesh. Acta Paediatrica
2010; 99: 389–393.
Sabetta, JR, et al.
Serum 25-hydroxyvitamin D and the incidence of acute viral respiratory tract infections in healthy adults. PLoS One
2010; 5: e11088.
Jartti, T, et al.
Low serum 25-hydroxyvitamin D levels are associated with increased risk of viral coinfections in wheezing children. Journal of Allergy and Clinical Immunology
2010; 126: 1074–1076.
Asamura, T, et al.
Low serum 1,25-dihydroxyvitamin D level and risk of respiratory infections in institutionalized older people. Gerontology
2010. 56: 542–543.
Berry, DJ, et al.
Vitamin D status has a linear association with seasonal infections and lung function in British adults. British Journal of Nutrition
2011; 106: 1433–1440.
Porojnicu, AC, et al.
Vitamin D status in healthy Romanian caregivers and risk of respiratory infections. Public Health Nutrition
2012; 15: 2157–2162.
Hirani, V. Associations between vitamin D and self-reported respiratory disease in older people from a nationally representative population survey. Journal of the American Geriatric Society
2013; 61: 969–973.
Karatekin, G, et al.
Association of subclinical vitamin D deficiency in newborns with acute lower respiratory infection and their mothers. European Journal of Clinical Nutrition
2009; 63: 473–477.
Camargo, CA, et al.
Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics
2011; 127: e180–187.
Belderbos, ME, et al.
Cord blood vitamin D deficiency is associated with respiratory syncytial virus bronchiolitis. Pediatrics
2011; 127: e1513–1520.
Morales, E, et al.
Maternal vitamin D status in pregnancy and risk of lower respiratory tract infections, wheezing, and asthma in offspring. Epidemiology
2012; 23: 64–71.
Li-Ng, M, et al.
A randomized controlled trial of vitamin D3 supplementation for the prevention of symptomatic upper respiratory tract infections. Epidemiology and Infection
2009; 137: 1396–1404.
Laaksi, I, et al.
Vitamin D supplementation for the prevention of acute respiratory tract infection: a randomized, double-blinded trial among young Finnish men. Journal of Infectious Diseases
2010; 202: 809–814.
Urashima, M, et al.
Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren. American Journal of Clinical Nutrition
2010; 91: 1255–1260.
Manaseki-Holland, S, et al.
Effects of vitamin D supplementation to children diagnosed with pneumonia in Kabul: a randomised controlled trial. Tropical Medicine and International Health
2010; 15: 1148–1155.
Murdoch, DR, et al.
Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial. Journal of the American Medical Association
2012; 308: 1333–1339.
Manaseki-Holland, S, et al.
Effect on the incidence of pneumonia of vitamin D supplementation by quarterly bolus dose to infants in Kabul: a randomised controlled superiority trial. Lancet
2012; 379: 1419–1427.
Camargo, CA, et al.
Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia. Pediatrics
2012; 130: e561–567.
Bjorkhem-Bergman, L, et al.
Serum levels of 25-hydroxyvitamin D and the CYP3A biomarker 4beta-hydroxycholesterol in a high-dose vitamin D supplementation study. Drug Metabolism and Disposition
2013; 41: 704–708.
de Gruijl, FR, Pavel, S. The effects of a mid-winter 8-week course of sub-sunburn sunbed exposures on tanning, vitamin D status and colds. Photochemical and Photobiological Sciences
2012; 11: 1848–1854.
Daynes, RA., et al.
Steroids as regulators of the mammalian immune response. Journal of Investigative Dermatology
1995; 105(1 Suppl): 14S–19S.
Kriesel, JD, Spruance, J. Calcitriol (1,25-dihydroxy-vitamin D3) coadministered with influenza vaccine does not enhance humoral immunity in human volunteers. Vaccine
1999; 17: 1883–1888.
Moe, SM, et al.
A placebo-controlled trial to evaluate immunomodulatory effects of paricalcitol. American Journal of Kidney Diseases
2001; 38: 792–802.
Chadha, MK, et al.
Effect of 25-hydroxyvitamin D status on serological response to influenza vaccine in prostate cancer patients. Prostate
2011; 71: 368–372.
Cooper, C, Thorne, A. Vitamin D supplementation does not increase immunogenicity of seasonal influenza vaccine in HIV-infected adults. HIV Clinical Trials
2011; 12: 275–276.
Momplaisir, F, et al.
Vitamin D levels, natural H1N1 infection and response to H1N1 vaccine among HIV-infected individuals. Journal of AIDS and Clinical Research
2012; 3: 152–159.
Principi, N, et al.
Impact of vitamin D administration on immunogenicity of trivalent inactivated influenza vaccine in previously unvaccinated children. Human Vaccines and Immunotherapeutics
2013; 9: 969–974.
Hollis, BW, Wagner, CL. The role of parent compound vitamin D with respect to metabolism and function: why clinical dose intervals can affect clinical outcomes. Journal of Clinical Endocrinology & Metabolism
2013; 98: 4619–4628.
Hart, PH, Gorman, S, Finlay-Jones, JJ. Modulation of the immune system by UV radiation: more than just the effects of vitamin D?
Nature Reviews Immunology
2011; 11: 584–596.
Milliken, SV, et al.
Effects of ultraviolet light on human serum 25-hydroxyvitamin D and systemic immune function. Journal of Allergy and Clinical Immunology
2012; 129: 1554–1561.