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Epidemiology and aetiology of acute bronchiolitis in Hong Kong infants

Published online by Cambridge University Press:  15 May 2009

R. Y. T. Sung ,
R. C. K. Chan ,
J. S. Tam ,
A. F. B. Cheng  and
H. G. S. Murray
R. Y. T. Sung
Affiliation:
Department of Paediatrics
R. C. K. Chan
Affiliation:
Microbiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong
J. S. Tam
Affiliation:
Microbiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong
A. F. B. Cheng
Affiliation:
Microbiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong
H. G. S. Murray
Affiliation:
Microbiology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong
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Summary

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The epidemiological, clinical and virological features of 1220 children with acute bronchiolitis admitted to the Prince of Wales Hospital, Hong Kong, from 1985 to 1988 are reported. They accounted for 6·6% of total paediatric admissions and provided a case incidence of bronchiolitis requiring admission to hospital of approximately 21 per 1000 children 0–24 months of age.

The clinical course and outcome was in general benign. The average hospital stay was 5 days and there were no deaths. Ten per cent of patients were repeatedly admitted to hospital with recurrent wheezing after discharge. Two infants developed bronchiolitis obliterans.

Respiratory syncytial virus (RSV) was shown by direct immunofluorescence, virus culture and serology to be the commonest cause of acute bronchiolitis in Hong Kong. Other aetiological agents included parainfluenza and influenza viruses, adenoviruses, and Mycoplasma pneumoniae.

In contrast to western countries, a seasonal variation of bronchiolitis was found with a peak incidence in the summer months. The significance of these observations is discussed.

Information

Type
Research Article
Information
Epidemiology & Infection , Volume 108 , Issue 1 , February 1992 , pp. 147 - 154
Copyright
Copyright © Cambridge University Press 1992

References

REFERENCES

1.Sung, RYT, Murray, HGS, Chan, RCK, Davies, DP, French, GL. Seasonal patterns of respiratory syncytial virus infection in Hong Kong: A preliminary report. J Infect Dis 1987; 156: 527–8.CrossRefGoogle Scholar
2.World Health Organisation. International classification of diseases, 9th revision. Geneva: World Health Organisation, 1980.Google Scholar
3.Leung, DTY, Tseng, RYM, Davies, DP. Setting up a clinical audit of paediatric morbidity in Hong Kong: Some early experience. Aust Paediatr J 1987; 23: 111–3.Google Scholar
4.Gardner, PS, McQuillin, J. Rapid virus diagnosis, 2nd ed.London: Butterworth, 1980: 94–5.Google Scholar
5.Hong, Kong 1986 By–Census: District Board constituency area summary tables. Hong Kong: Census and Statistics Department, 1987; 204–60.Google Scholar
6.Kim, HW, Arrobio, JO, Brandt, CD et al. , Epidemiology of respiratory syncytial virus infection in Washington, DC. Am J Epidemiol 1973; 98: 216–25.CrossRefGoogle Scholar
7.Martin, AJ, Gardner, PS, McQuillin, J. Epidemiology of respiratory viral infection among paediatric inpatients over a six-year period in North-east England. Lancet 1978; II: 1035–8.CrossRefGoogle Scholar
8.McConnochie, KM. Bronchiolitis: what's in the name? Am J Dis Child 1983; 137: 11–13.CrossRefGoogle ScholarPubMed
9.Gardner, PS. How etiologic, pathologic and clinical diagnoses can be made in a correlated fashion. Paediat Res 1977; 11: 254–61.Google Scholar
10.Disney, ME, Sandiford, BR, Cragg, J, Wolff, J. Epidemic bronchiolitis in infants. BMJ 1960; 1: 1407–11.CrossRefGoogle ScholarPubMed
11.Heycock, JB, Noble, TC. 1230 cases of acute bronchiolitis in infancy. BMJ 1962; 2: 879–81.Google Scholar
12.Simpson, H. Bronchiolitis. In: Forfar, JO, Arneil, GC, ed. Textbook of pediatrics, 3rd edn.London: Churchill Livingstone, 1984: 548.Google Scholar
13.Wong, HB, Aiyathurai, Jej, Tay, JSH et al. , Acute bronchiolitis in infancy. J Singapore Paed Soc 1983; 25: 89–95.Google ScholarPubMed
14.Denny, FW, Collier, AM, Henderson, FW, Clyde, W. The epidemiology of bronchiolitis. Pediatr Res 1977; 11: 234–6.Google ScholarPubMed
15.Mok, JY, Simpson, H. Outcome of acute lower respiratory tract infection in infants: preliminary report of seven-year follow-up study. BMJ 1982; 285: 333–7.CrossRefGoogle ScholarPubMed
16.Mok, JY, Simpson, H. Outcome for acute bronchitis, bronchiolitis and pneumonia in infancy. Arch Dis Child 1984; 59: 306–9.CrossRefGoogle ScholarPubMed
17.Pullan, CR, Hey, EN. Wheezing, asthma and pulmonary dysfunction ten years after infection with respiratory syncytial virus in infancy. BMJ 1982; 284: 1665–9.CrossRefGoogle Scholar
18.Sims, DG, Downham, Maps, Gardner, PS, Webb, JKG, Weightman, D. Study of 8-year-old children with a history of respiratory syncytial virus bronchiolitis in infancy. BMJ 1978; 1: 11–14.CrossRefGoogle ScholarPubMed
19.Henderson, FW, Clyde, WA, Collier, AM et al. , The etiologic and epidemiologic spectrum of bronchiolitis in pediatric practice. J Pediatr 1979; 95: 183–90.CrossRefGoogle ScholarPubMed
20.Berman, S, Duenas, A, Bedoya, A et al. , Acute lower respiratory tract illness in Cali, Colombia: A two–year ambulatory study. Pediatrics 1983; 71: 210–8.CrossRefGoogle ScholarPubMed
21.Chanock, RM, Kim, HW, Vargosko, A et al. , Respiratory syncytial virus. I. Virus recovery and other observations during 1960 outbreak of bronchiolitis, pneumonia and minor respiratory diseases in children. JAMA 1961; 176: 647–53.Google ScholarPubMed
22.Wong, KW, Davies, DP. Seasonal variations in asthmatic admission. Hong Kong J Paed 1985; 2. 19–23.Google Scholar
23.Leer, JA Jr., Green, JL, Heimlich, EM et al. , Corticosteroid treatment in bronchiolitis: A controlled, collaborative study in 297 infants and children. Am J Dis Child 1969; 117: 495–503.CrossRefGoogle ScholarPubMed
24.De Silva, LM, Hanlow, MG. Respiratory syncytial virus: A report of a 5-year study at a children's hospital. J Med Virol 1986; 19: 299–305.CrossRefGoogle ScholarPubMed
25.Spence, L, Barratt, N. Respiratory syncytial virus associated with acute respiratory infections in Trinidadian patients. Am J Epidemiol 1968; 88: 257–66.CrossRefGoogle ScholarPubMed
26.Cherian, T, Simoes, Eaf, Steinhoff, MC et al. , Bronchiolitis in tropical south India. Am J Dis Child 1990; 144: 1026–30.Google ScholarPubMed