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Estimating the prevalence of active Helicobacter pylori infection in a rural community with global positioning system technology-assisted sampling

  • E. J. MELIUS (a1) (a2), S. I. DAVIS (a3), J. T. REDD (a2), M. LEWIN (a3), R. HERLIHY (a4), A. HENDERSON (a3), J. SOBEL (a5), B. GOLD (a5) (a6) and J. E. CHEEK (a2)...

We investigated a possible outbreak of H. pylori in a rural Northern Plains community. In a cross-sectional survey, we randomly sampled 244 households from a geocoded emergency medical system database. We used a complex survey design and global positioning system units to locate houses and randomly selected one eligible household member to administer a questionnaire and a 13C-urea breath test for active H. pylori infection (n = 166). In weighted analyses, active H. pylori infection was detected in 55·0% of the sample. Factors associated with infection on multivariate analysis included using a public drinking-water supply [odds ratio (OR) 12·2, 95% confidence interval (CI) 2·9–50·7] and current cigarette smoking (OR 4·1, 95% CI 1·7–9·6). People who lived in houses with more rooms, a possible indicator of decreased crowding in the home, were less likely to have active H. pylori infections (OR 0·7, 95% CI 0·5–0·9 for each additional room).

Corresponding author
*Author for correspondence: Ms. E. J. Melius, 3311 NE 163rd Street, Lake Forest Park, WA 98155, USA. (Email:
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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