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Experimental model of oral antityphoid vaccination with live streptomycin-dependent Salmonella typhimurium in C57BL/6 mice

  • I. R. Vladoianu (a1) and F. Dubini (a1)
Summary
SUMMARY

The present experimental model offered the opportunity to study particular aspects concerning the avirulence stability of live streptomycin-dependent (Sm D) Salmonella vaccines, under conditions resembling human enteric fever. The results seem to indicate that, in practice, the risk of reversion to a virulent form during oral antityphoid vaccination with Sm D strains remains slight even after the interruption of concomitant streptomycin administration.

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L.S. Baron & S. B. Formal (1960). Immunization studies with living vaccine of Salmonella typhimurium. Proceedings of the Society for Experimental Biology and Medicine 104, 565–7.

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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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