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The first dominant co-circulation of both dengue and chikungunya viruses during the post-monsoon period of 2010 in Delhi, India

  • P. SINGH (a1), V. MITTAL (a2), M. M. A. RIZVI (a3), M. CHHABRA (a2), P. SHARMA (a2), D. S. RAWAT (a1), D. BHATTACHARYA (a2), L. S. CHAUHAN (a1) (a2) and A. RAI (a1)...
Summary

Independent outbreaks of dengue virus (DENV) infection and sporadic cases of chikungunya virus (CHIKV) have been recorded in the metropolitan city of Delhi on several occasions in the past. However, during a recent 2010 arboviral outbreak in Delhi many cases turned negative for DENV. This prompted us to use duplex reverse transcriptase–polymerase chain reaction (D-RT–PCR) to establish the aetiology of dengue/chikungunya through sequencing of CprM and E1 genes of dengue and chikungunya viruses. Interestingly, for the first time, both DENV and CHIKV co-circulated simultaneously and in equally dominant proportion during the post-monsoon period of 2010. DENV-1 genotype III and the East Central South African genotype of CHIKV were associated with post-monsoon spread of these viruses.

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Corresponding author
*Author for correspondence: Dr A. Rai, Joint Director & Head, Division of Biochemistry & Biotechnology, National Centre for Disease Control (Formerly NICD) 22, Sham Nath Marg, Delhi-110054, India. (Email: arvindrai_16@hotmail.com)
References
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1.Dash, PK, et al. Development and evaluation of a 1-step duplex reverse transcription polymerase chain reaction for differential diagnosis of chikungunya and dengue infection. Diagnostic Microbiology and Infectious Disease 2008; 62: 5257.
2.Sabin, AB. Research on dengue during World War II. American Journal of Tropical Medicine and Hygiene 1952; 1: 3050.
3.Dar, L, et al. The first major outbreak of dengue hemorrhagic fever in Delhi. Emerging Infectious Diseases 1999; 5: 589590.
4.Kumar, M, et al. Unusual emergence of Guate98-like molecular subtype of Den-3 during 2003 dengue outbreak in Delhi. Dengue Bulletin 2004; 28: 161167.
5.Kukreti, H, et al. Emergence of an independent lineage of dengue virus type 1 (DENV-1) and its co-circulation with predominant DENV-3 during the 2006 dengue fever outbreak in Delhi. International Journal of Infectious Diseases 2008; 12: 542549.
6.Ross, RW. The Newala epidemic III; the virus: isolation, pathogenic properties and relationship to the epidemic. Journal of Hygiene 1956; 54: 177191.
7.Yergolkar, PN, et al. Chikungunya outbreaks caused by African genotype, India. Emerging Infectious Diseases 2006; 12: 15801583.
8.Schuffenecker, I, et al. Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak. PLoS Medicine 2006; 3: e263.
9.Chhabra, M, et al. Chikungunya fever: a reemerging viral infection. Indian Journal of Medical Microbiology 2008; 26: 5–12.
10.Myers, RM, Carey, DE. Concurrent isolation from patient of two arboviruses, chikungunya and dengue type 2. Science1967; 157: 13071308.
11.Chahar, HS, et al. Co-infections with chikungunya virus and dengue virus in Delhi, India. Emerging Infectious Diseases 2009; 15: 10771080.
12.Dar, L, et al. Co-circulation of dengue serotypes, Delhi, India, 2003. Emerging Infectious Diseases 2006; 12: 352353.
13.NVBDCP. Chikungunya fever (http://www.nvbdcp.gov.in/Chikun-cases.html). Accessed 19 April 2011.
14.Powers, AM, et al. Re-emergence of chikungunya and o'nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationships. Journal of General Virology 2000; 1: 471479.
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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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