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High risk of a large measles outbreak despite 30 years of measles vaccination in The Netherlands

  • L. MOLLEMA (a1), G. P. SMITS (a1), G. A. BERBERS (a1), F. R. VAN DER KLIS (a1), R. S. VAN BINNENDIJK (a1), H. E. DE MELKER (a1) and S. J. M. HAHNÉ (a1)
  • DOI: http://dx.doi.org/10.1017/S0950268813001532
  • Published online: 06 August 2013
Abstract
SUMMARY

Our aim was to assess progress towards measles elimination from The Netherlands by studying humoral measles immunity in the Dutch population. A population-based seroepidemiological study was conducted in 2006–2007 (N = 7900). Serum samples were analysed by a bead-based multiplex immunoassay. IgG levels ⩾0·2 IU/ml were considered protective. The overall seroprevalence in the Dutch population was 96%. However, 51% of socio-geographically clustered orthodox Protestant individuals aged <10 years were susceptible. Infants might be susceptible to measles between ages 4 months and 14 months, the age at which maternal antibodies have disappeared and the first measles, mumps, rubella (MMR) vaccination is administered, respectively. Waning of antibody concentrations was slower after the second MMR vaccination than after the first. The Netherlands is at an imminent risk of a measles outbreak in the orthodox Protestant minority. To prevent subsequent transmission to the general population, efforts to protect susceptible age groups are needed.

Copyright
Corresponding author
*Author for correspondence: Dr L. Mollema, National Institute for Public Health and the Environment, Epidemiology and Surveillance Unit, P.O. Box 1 (internal P.O. Box 75), 3720 BA Bilthoven, The Netherlands. (Email: Liesbeth.Mollema@rivm.nl)
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This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

1.E Simons , Assessment of the 2010 global measles mortality reduction goal: results from a model of surveillance data. Lancet 2012; 379: 21732178.

3. NKhetsuriani , Supplementary immunization activities to achieve measles elimination: experience of the European region. Journal Infectious Diseases 2011; 204 (Suppl. 1): 343352.

5.M Muscat . Who gets measles in Europe? Journal Infectious Diseases 2011; 204 (Suppl. 1): 353365.

7.WL Ruijs , Religious subgroups influencing vaccination coverage in the Dutch Bible belt: an ecological study. BMC Public Health 2011; 11: 102.

11. SVan den Hof , MAEConyn-van Spaendonck , JEvan Steenbergen . Measles epidemic in the Netherlands, 1999–2000. Journal Infectious Diseases 2002; 186: 14831486.

12. SHahné , Measles outbreak, the Netherlands, 2008. Emerging Infectious Diseases 2010; 16: 567568.

13.S Van den Hof , Sero-epidemiologic study of measles antibodies in the Netherlands, a cross-sectional study in a national sample and in municipalities with low vaccine coverage. Vaccine 2000; 18: 931940.

14.HE De Melker , MA Conyn-van Spaendonck . Immunosurveillance and the evaluation of national immunization programmes: a population-based approach. Epidemiology and Infection 1998; 121: 637643.

16.GP Smits , Development of a bead-based multiplex immunoassay for the simultaneously quantitative detection of IgG serum antibodies against measles, mumps, rubella and varicella zoster. Clinical Vaccine Immunology 2012; 19: 396400.

17.RT Chen , Measles antibody: reevaluation of protective titers. Journal Infectious Diseases 1990; 162: 10361042.

21.WLM Ruijs , Measuring vaccination coverage in a hard to reach minority. European Journal of Public Health 2012; 22: 359364.

23.NJ Gay . The theory of measles elimination: implications for the design of elimination strategies. Journal Infectious Diseases 2004; 189 (Suppl. 1): 2735.

24.J Wallinga , JCM Heijne , M Kretzschmar . A measles epidemic threshold in a highly vaccinated population. PLoS Medicine 2005; 2: e316.

25.MS Bartlett . The critical community size for measles in the United States. Journal of the Royal Statistical Society. Series A (General) 1960; 123: 3744.

26. WLRuijs , How orthodox protestant parents decide on the vaccination of their children: a qualitative study. BMC Public Health 2012; 12: 408.

27.WL Ruijs , How healthcare professionals respond to parents with religious objections to vaccination: a qualitative study. BMC Health Services Research 2012; 12: 231.

29.S Van den Hof , Options for improvement of the Dutch measles vaccination schedule. Vaccine 2003; 21: 721724.

30.MS Lee , Measles seroepidemiology and decay rate of vaccine-induced measles IgG titers in Taiwan, 1995–1997. Vaccine 2007; 19: 46444651.

33.C Poethko-Müller , A Mankertz . Sero-epidemiology of measles-specific IgG antibodies and predictive factors for low or missing titers in a German population-based cross-sectional study in children and adolescents (KiGGS). Vaccine 2011; 29: 79497959.

34. BChristenson , MBöttiger . Measles antibody: comparison of long-term vaccination titres, early vaccination titres and naturally acquired immunity to and booster effects on the measles virus. Vaccine 1994; 12: 129133.

35.C Amela , I Pachón , F de Ory . Evaluation of measles, mumps and rubella immunisation programme in Spain by using a sero-epidemiological survey. European Journal of Epidemiology 2003; 18: 7179.

36.J Mossong , L Putz , F Schneider . Seroprevalence of measles, mumps and rubella antibodies in Luxembourg: results from a national cross-sectional study. Epidemiology and Infection 2003; 132: 1118.

37.I Davidkin , Persistence of measles, mumps, and rubella antibodies in an MMR-vaccinated cohort: a 20-year follow-up. Journal of Infectious Diseases 2008; 197: 950956.

38.MC Rota , Measles serological survey in the Italian population: interpretation of results using a mixture model. Vaccine 2008; 26: 44034409.


40.RA Parker , DD Erdman , LJ Anderson . Use of mixture models in determining laboratory criterion for identification of seropositive individuals: application to parvovirus B19 serology. Journal of Virological Methods 1990; 27: 135144.


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Epidemiology & Infection
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