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Lyme disease: a search for a causative agent in ticks in south–eastern Australia

  • R. C. Russell (a1), S. L. Doggett (a1), R. Munro (a2), J. Ellis (a3), D. Avery (a1), C. Hunt (a4) and D. Dickeson (a5)
  • DOI:
  • Published online: 01 May 2009

Attempts were made to identify the causative organism of Lyme disease in Australia from possible tick vectors.

Ticks were collected in coastal areas of New South Wales, Australia, from localities associated with putative human infections. The ticks were dissected; a portion of the gut contents was examined for spirochaetes by microscopy, the remaining portion inoculated into culture media. The detection of spirochaetes in culture was performed using microscopy, and immunochemical and molecular (PCR) techniques. Additionally, whole ticks were tested with PCR for spirochaetes.

From 1990 to 1992, approximately 12000 ticks were processed for spirochaetes. No evidence of Borrelia burgdorferi or any other spirochaete was recovered from or detected in likely tick vectors. Some spirochaete–like objects detected in the cultures were shown to be artifacts, probably aggregates of bacterial flagellae.

There is no definitive evidence for the existence in Australia of B. burgdorferi the causative agent of true Lyme disease, or for any other tick–borne spirochaete that may be responsible for a local syndrome being reported as Lyme disease.

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JH Oliver , MR Owsley , HJ Hutcheson , Conspecificity of the ticks Ixodes scapularis and I. dammini (Acari: Ixodidae). J Med Entomol 1993; 30: 5463.

DW Rahn , SE Malawista . Lyme disease: recommendations for diagnosis and treatment. Ann Intern Med 1991; 114: 472–81.

LH Sigal , AS Curran . Lyme disease: a multifocal worldwide epidemic. Annu Rev Publ Health 1991; 12: 85109.

DH Persing , SR Telford III, PN Rys , Detection of Borrelia burgdorferi DNA in museum specimens of Ixodes dammini ticks. Science 1990; 249: 1420–3.

U Edwards , T Rogall , H Blocker , M Emde , EC Bottger . Isolation and direct complete nucleotide determination of entire genes. Characterisation of a gene coding for 16S ribosomal RNA. Nucleic Acids Res 1989; 17: 7843–53.

J Piesman , BF Stone . Vector competence of the Australian paralysis tick, Ixodes holocyclus, for the Lyme disease spirochaete Borrelia burgdorferi. Int J Parasitol 1991; 21: 109–11.

MJ Mackerras . The haematozoa of Australian mammals. Aust J Zool 1959; 7: 105–35.

D Berg , KG Abson , NS Prose . The laboratory diagnosis of Lyme disease. Arch Dermatol 1991; 127: 866–70.

EC Guy , RG Farquhar . Borrelia burgdorferi in urban parks. Lancet 1991; 338: 253.

MM Huycke , DD D'Alessio , JJ Marx . Prevalence of antibody to Borrelia burgdorferi by indirect fluorescent antibody assay, ELISA, and western immunoblot in healthy adults in Wisconsin and Arizona. J Infect Dis 1992; 165: 1133–7.

H Kuiper , BM de Jongh , AP Nauta , Lyme disease in Dutch forestry workers. J Infect 1991; 23: 279–86.

AG Barbour , D Fish . The biological and social phenomenon of Lyme disease. Science 1993; 260: 1610–16.

A Krause , GR Burmester , A Rensing , Cellular immune reactivity to recombinant OspA and flagellin from Borrelia burgdorferi in patients with Lyme disease. Complexity of humoral and cellular responses. J Clin Invest 1992; 90: 1077–84.

G Zumstein , R Fuchs , A Hofman , V Preac-Mursic , E Soulschek , B Wilske . Genetic polymorphism of the gene encoding the outer surface protein A (OspA) of Borrelia burgdorferi. Med Microbiol Immunol 1992; 181: 5770.

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Epidemiology & Infection
  • ISSN: 0950-2688
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