Skip to main content Accessibility help
×
Home

Mycoplasmas in the urine of HIV-1 infected men

  • W. JIAN-RU (a1), W. BEI (a1), C. HAO (a1), X. JIN-SHUI (a2) and H. XI-PING (a2)...

Summary

The aim of this study was determine the prevalence of Mycoplasma hominis, M. genitalium, M. fermentans, M. pirum, M. penetrans and Ureaplasma urealyticum in HIV-infected patients. Culture and PCR were used to detect six species of Mycoplasma in first-void urine of HIV-1 infected men. A total of 497 HIV/AIDS patients (age range 5–75 years, mean 37 years) were screened in the study. All presented positive for at least one kind of mycoplasma, especially U. urealyticum and M. hominis. Six mycoplasmas were significant in the homosexual contact and heterosexual contact groups. The distribution of M. hominis, M. penetrans, and M. pirum were significantly different in this four-transmission category. CD4+ cell count levels were lower in the AIDS-associated Mycoplasma-positive group than in the Mycoplasma-negative group (P<0·01). This study indicates that U. urealyticum, M. hominis and M. fermentans are prevalent in HIV-1-infected male patients. This may be an indication of whether mycoplasmas are co-factors in the progression of HIV disease.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Mycoplasmas in the urine of HIV-1 infected men
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Mycoplasmas in the urine of HIV-1 infected men
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Mycoplasmas in the urine of HIV-1 infected men
      Available formats
      ×

Copyright

Corresponding author

*Author for correspondence: Professor W. Bei, Department of Epidemiology and Statistics, School of Public Health, Southeast University, Nanjing, Jiangsu, People's Republic of China. (Email: wangbeilxb@seu.edu.cn)

References

Hide All
1.Barre-Sinoussi, FJC, et al. Isolation of a T-lymphotropic retrovirus from a patient at risk for AIDS. Science 1983; 220: 868874.
2.Clavel, FD, et al. Isolation of a new human retrovirus from West African patients with AIDS. Science 1986; 233: 343346.
3.Odile, G, et al. A Longitudinal study of seroreactivity against Mycoplasma penetrans in HIV-infected homosexual men: association with disease progression. AIDS Research and Human Retroviruses 1998; 14: 661667.
4.Blanchard, A, Montagnier, L. AIDS-associated mycoplasmas. Annual Review of Microbiology 1994; 48: 687712.
5.Blanchard, A. Mycoplasmas and HIV infection, a possible interaction through immune activation. Wiener Klinische Wochenschrift 1997; 109: 590593.
6.Taylor-Robinson, D, et al. Detection of several mycoplasma species at various anatomical sites of homosexual men. European Journal of Clinical Microbiology and Infectious Diseases 2003; 22: 291293.
7.Kovacic, R, et al. Search for the presence of six mycoplasma species in peripheral blood mononuclear cells of subjects seropositive and seronegative for human immunodeficiency virus. Journal of Clinical Microbiology 1996; 34: 18081810.
8.Ainsworth, JG, et al. Mycoplasma species in rapid and slow HIV progressors. International Journal of STD & AIDS 2000; 11: 7679.
9.Loubinoux, J, et al. Genital mycoplasmas in patients with acquired immunodeficiency syndrome. New Microbiology 1998; 21: 403405.
10.Ainsworth, JG, et al. An association of disseminated Mycoplasma fermentans in HIV-1 positive patients with non-Hodgkin's lymphoma. International Journal of STD & AIDS 2001; 12: 499504.
11.Cultrera, R, et al. Use of PCR to detect mycoplasma DNA in respiratory tract specimens from adult HIV-positive patients. Journal of Medical Microbiology 1998; 47: 983986.
12.Martinelli, F, et al. Increased frequency of detection of Ureaplasma urealyticum and Mycoplasma genitalium in AIDS patients without urethral symptoms. Journal of Clinical Microbiology 1999; 6: 20422044.
13.Guo, HJ, Yang, HT, Wang, B. Distribution of mycoplasmas infection among 175 HIV/AIDS patients in Jiangsu province. Chinese Journal of Epidemiology 2007; 28: 932933.
14.da Costa, FAM, et al. Prevalence of Mycoplasma genitalium among HIV-infected men in Sao Paulo city detected by realtime polymerase chain reaction. International Journal of STD & AIDS 2010; 21: 2325.
15.Soni, S, et al. The prevalence of urethral and rectal Mycoplasma genitalium and its associations in men who have sex with men attending a genitourinary medicine clinic. Sexually Transmitted Infections 2010; 86: 2124.

Keywords

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed