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National patterns of Escherichia coli O157 infections, USA, 1996–2011

  • S. V. SODHA (a1), K. HEIMAN (a1) (a2), L. H. GOULD (a1), R. BISHOP (a1), M. IWAMOTO (a1), D. L. SWERDLOW (a1) and P. M. GRIFFIN (a1)...

US public health laboratories began reporting Escherichia coli O157 isolates to CDC in 1996. We describe temporal and geographical patterns of isolates reported from 1996 to 2011 and demographics of persons whose specimens yielded isolates. We calculated annual E. coli O157 isolation rates/100 000 persons by patient's state of residence, county of residence, age, and sex using census data. The average annual isolation rate was 0·84. The average isolation rate in northern states (1·52) was higher than in southern states (0·43). Counties with ⩾76% rural population had a lower isolation rate (0·67) than counties with ⩽25%, 26–50%, and 51–75% rural populations (0·81, 0·92, and 0·81, respectively). The highest isolation rate (3·19) was in children aged 1–4 years. Infections were seasonal with 49% of isolates collected during July to September. Research into reasons for higher incidence in northern states and for seasonality could guide strategies to prevent illnesses.

Corresponding author
*Author for correspondence: S. V. Sodha, MD, MPH, 1600 Clifton Road, MS A-04, Atlanta, GA 30333, USA. (Email:
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2. L Slutsker , Escherichia coli O157:H7 diarrhea in the United States: clinical and epidemiologic features. Annals of Internal Medicine 1997; 126: 505513.

3. J Hilbe . Negative Binomial Regression, 2nd edn. New York: Cambridge University Press, 2011.

5. TG Boyce , DL Swerdlow , PM Griffin . Escherichia coli O157:H7 and the hemolytic-uremic syndrome. New England Journal of Medicine 1995; 333: 364368.

7. J Bender , Factors affecting surveillance data on Escherichia coli O157 infections collected from FoodNet sites, 1996–1999. Clinical Infectious Diseases 2004; 38: S157S164.

10. M Rivas , Characterization and epidemiologic subtyping of Shiga toxin-producing Escherichia coli strains isolated from hemolytic uremic syndrome and diarrhea cases in Argentina. Foodborne Pathogens and Disease 2006; 3: 8896.

11. M Rivas , Risk factors for sporadic Shiga toxin-producing Escherichia coli infections in children, Argentina. Emerging Infectious Diseases 2008; 14: 763771.

15. T Edrington , Seasonal shedding of Escherichia coli O157:H7 in ruminants: a new hypothesis. Foodborne Pathogens and Disease 2006; 3: 413421.

16. C Frank , Cattle density and Shiga toxin-producing Escherichia coli infection in Germany: increased risk for most but not all serogroups. Vector-Borne and Zoonotic Diseases 2008; 8: 635643.

22. M Williams , Determining relationships between the seasonal occurrence of Escherichia coli O157:H7 in live cattle, ground beef, and humans. Foodborne Pathogens and Disease 2010; 7: 12471254.

25. A Voetsch , Laboratory practices for stool-specimen culture for bacterial pathogens, including Escherichia coli O157:H7, in the FoodNet sites, 1995–2000. Clinical Infectious Diseases 2004; 38: S190S197.

30. C Barton Behravesh , 2008 outbreak of Salmonella Saintpaul infections associated with raw produce. New England Journal of Medicine 2011; 364: 918927.

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Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
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