Skip to main content
×
Home
    • Aa
    • Aa

Pre-existing medical conditions associated with Vibrio vulnificus septicaemia

  • M. P. MENON (a1), P. A. YU (a1), M. IWAMOTO (a1) and J. PAINTER (a1)
Abstract
SUMMARY

Vibrio vulnificus (Vv) can result in severe disease. Although pre-existing liver disease is a recognized risk factor for serious infection, the relative importance of other comorbidities has not been fully assessed. We analysed reports of Vv infections submitted to CDC from January 1988 to September 2006 in order to assess the role of pre-existing conditions contributing to severe outcomes. A total of 1212 patients with Vv infection were reported. Only patients with liver disease [adjusted odds ratio (aOR) 5·1)] were more likely to become septic when exposure was due to contaminated food. Patients with liver disease (aOR 4·1), a haematological disease (aOR 3·2), or malignancy (aOR 3·2) were more likely to become septic when infection was acquired via a non-foodborne exposure. As such, patients with these pre-existing medical conditions should be advised of the risk of life-threatening illness after eating undercooked contaminated seafood or exposing broken skin to warm seawater.

Copyright
Corresponding author
*Author for correspondence: Dr M. P. Menon, 1600 Clifton Road, MS A06, Atlanta, GA 30329, USA. (Email: manoj@u.washington.edu)
Linked references
Hide All

This list contains references from the content that can be linked to their source. For a full set of references and notes please see the PDF or HTML where available.

2. PA Blake , Disease caused by a marine Vibrio: clinical characteristics and epidemiology. New England Journal of Medicine 1979; 300: 15.

3. E Scallan , Foodborne illness acquired in the United States – major pathogens. Emerging Infectious Diseases 2011; 17: 715.

5. MA Horseman , S Surani . A comprehensive review of Vibrio vulnificus: an important cause of severe sepsis and skin and soft-tissue infection. International Journal of Infectious Diseases 2011; 15: e157166.

7. M Iwamoto , Epidemiology of seafood-associated infections in the United State. Clinical Microbiology Reviews 2010; 23: 399411.

9. A Newton , Increased rates of vibriosis in the United States, 1996–2010: review of surveillance data from 2 systems. Clinical Infectious Diseases 2012; 54 (Suppl. 5): S391395.

10. MK Jones , JD Oliver . Vibrio vulnificus: disease and pathogenesis. Infection and Immunity 2009; 77: 17231733.

11. AM Dechet , Nonfoodborne Vibrio infections: an important cause of morbidity and mortality in the United States, 1997–2006. Clinical Infectious Diseases 2008; 46: 970976.

Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords:

Metrics

Full text views

Total number of HTML views: 2
Total number of PDF views: 20 *
Loading metrics...

Abstract views

Total abstract views: 102 *
Loading metrics...

* Views captured on Cambridge Core between September 2016 - 24th May 2017. This data will be updated every 24 hours.