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The prevalence of hepatitis B and C in an antenatal population of various ethnic origins

Published online by Cambridge University Press:  19 October 2009

E. Boxall
Affiliation:
Regional Virus Laboratory, Public Health Laboratory, Birmingham Heartlands Hospital, Birmingham B9 5SS
S. Skidmore
Affiliation:
Regional Virus Laboratory, Public Health Laboratory, Birmingham Heartlands Hospital, Birmingham B9 5SS
C. Evans
Affiliation:
Regional Virus Laboratory, Public Health Laboratory, Birmingham Heartlands Hospital, Birmingham B9 5SS
S. Nightingale
Affiliation:
Midlands Centre for Neurosurgery and Neurology, Smethwick, West Midlands B67 7JX
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Summary

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A total of 3522 samples of serum, collected anonymously from women attending an antenatal clinic, was tested for hepatitis B surface antigen and antibody to hepatitis C. The prevalence of anti-HCV was low; only five confirmed positives were found (0·14%). The prevalence of hepatitis B overall was 0·56%, but was 1·04% in women from immigrant groups. Hepatitis B carriage is therefore four times more common than hepatitis C carriage in the antenatal population comprised of various ethnic origins. The patterns of infection in the two viruses are reversed, hepatitis B being more common in Asian, S.E. Asian and West Indian mothers and hepatitis C being more common in mothers of white Caucasian origin. Routine antenatal screening for anti-HCV is discussed.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1994

References

1.Derso, A, EH, Boxall, MJ, Tarlow, Th, Flewett. Transmission of HBsAg from mother to infant in four ethnic groups. BMJ 1978; 1: 949–52.Google ScholarPubMed
2.Sm, Wheeley, Pt, Jackson, Eh, Boxall et al. Prevention of perinatal transmission of hepatitis B virus (HBV): a comparison of two prophylactic schedules. J Med Virol 1991; 35: 212–15.Google Scholar
3.Nightingale, S, Orton, D, KW, Ratcliffe et al. Antenatal survey for the seroprevalence of HTLV-1 infections in the West Midlands, England. Epidemiol Infect 1993; 110: 379–87.Google ScholarPubMed
4.Mawson, S, Skidmore, S, Pandov, H, Desselberger, U. Anonymous testing for HIV infection. Lancet 1990; i: 858–9.Google Scholar
5.Szmuness, W, Ej, Harley, Ikram, H, Ce, Stevens. Sociodemographic aspects of the epidemiology of hepatitis B. In: Gn, Vyas, Sn, Cohen, R, Schmid, eds. Viral hepatitis. Philadelphia: Franklin Institute Press, 1978: 297311.Google Scholar
6.Nishioka, K. Predominant mode of transmission of hepatitis B virus: perinatal transmission in Asia. In: Gn, Vyas, Jl, Dienstag, JH, Hoofnagle, eds. Viral hepatitis and liver diseases. Orlando, Florida: Grune and Stratton, 1984: 423–32.Google Scholar
7.Jph, Lam,Mcomish, F, Sm, Burns et al. Infrequent vertical transmission of hepatitis C virus. J Inf Dis 1993; 167: 572–6.Google Scholar
8.Sj, Skidmoro. Hepatitis C virus – epidemiology and serological diagnosis. J Med Microbiol 1993; 39: 321–2.Google Scholar